Omnipresent Atherosclerotic Disease: Time to Depart From Analysis of Individual Vascular Beds

2012 ◽  
Vol 79 (6) ◽  
pp. 641-653 ◽  
Author(s):  
Fumiyuki Otsuka ◽  
Valentin Fuster ◽  
Jagat Narula ◽  
Renu Virmani
Keyword(s):  
Atherosclerotic Disease ◽  
Vascular Beds

An ultrastructural analysis of the sympathetic innervation of the rabbit ear artery and middle cerebral artery and their branches

1992 ◽  
Vol 50 (1) ◽  
pp. 934-935
Author(s):  
John T. Dodge ◽  
John A. Bevan
Keyword(s):  
Middle Cerebral Artery ◽  
Cerebral Artery ◽  
Sympathetic Innervation ◽  
Electrical Field Stimulation ◽  
Rabbit Ear Artery ◽  
Electrical Field ◽  
Functional Differences ◽  
Ear Artery ◽  
Rabbit Ear ◽  
Vascular Beds

Unlike many peripheral vascular beds, the sympathetic nervous system exerts little control on cerebral blood flow. The contractile response of isolated rabbit middle cerebral artery (MCA) segments to electrical field stimulation of its intramural nerves is less than in a similar-sized artery from the ear. This study was undertaken to characterize and compare the perivascular neuromuscular relationships and innervation density of similar-sized arteries varying in diameter from these two different regional arterial beds to see if there were structural correlates for these functional differences.

Adrenergic Stimulation of Regional Plasminogen Activator Release in Rabbits

1992 ◽  
Vol 68 (05) ◽  
pp. 545-549 ◽  
Author(s):  
W L Chandler ◽  
S C Loo ◽  
D Mornin
Keyword(s):  
Lower Extremity ◽  
Plasminogen Activator ◽  
Beta Blocker ◽  
Time Course ◽  
Vascular System ◽  
Adrenergic Stimulation ◽  
Epinephrine Administration ◽  
Adrenergic Antagonist ◽  
Vascular Beds ◽  
Stimulation Of

SummaryThe purpose of this study was to determine whether different regions of the rabbit vascular system show variations in the rate of plasminogen activator (PA) secretion. To start, we evaluated the time course, dose response and adrenergic specificity of PA release. Infusion of 1 µg/kg of epinephrine stimulated a 116 ± 60% (SD) increase in PA activity that peaked 30 to 60 s after epinephrine administration. Infusion of 1 µg/kg of norepinephrine, isoproterenol and phenylephrine had no effect on PA activity. Pretreatment with phentolamine, an alpha adrenergic antagonist, blocked the release of PA by epinephrine while pretreatment with the beta blocker propranolol had no effect. This suggests that PA release in the rabbit was mediated by some form of alpha receptor.Significant arterio-venous differences in basal PA activity were found across the pulmonary and splanchnic vascular beds but not the lower extremity/pelvic bed. After stimulation with epinephrine, PA activity increased 46% across the splanchnic bed while no change was seen across the lower extremity/pelvic bed. We conclude that several vascular beds contribute to circulating PA activity in the rabbit, and that these beds secrete PA at different rates under both basal and stimulated conditions.

Vascular Endothelial Growth Factor (VEGF165) and Its Influence on Angiogenesis Versus Arteriogenesis in Different Vascular Beds

2002 ◽  
Vol 9 (6) ◽  
pp. 842-854 ◽  
Author(s):  
Sigrid Nikol ◽  
Jaroslav Pelisek ◽  
Markus G. Engelmann ◽  
Masumi Shimizu ◽  
Alexandra Fuchs ◽  
...  
Keyword(s):  
Vascular Endothelial Growth Factor ◽  
Growth Factor ◽  
Vascular Endothelial ◽  
Vascular Beds ◽  
Endothelial Growth Factor

Statins May Prevent Atherosclerotic Disease in OSA Patients without Co-Morbidities?

2016 ◽  
Vol 15 (1) ◽  
pp. 5-9 ◽  
Author(s):  
Domenico Toraldo ◽  
Michele Benedetto ◽  
Luana Conte ◽  
Francesco Nuccio
Keyword(s):  
Atherosclerotic Disease

Relationship of asymmetric dimethylarginine to dialysis treatment and atherosclerotic disease

2001 ◽  
Vol 59 (s78) ◽  
pp. 9-13 ◽  
Author(s):  
Jan T. Kielstein ◽  
Stefanie M. Bode-Boger ◽  
Jurgen C. Frolich ◽  
Hermann Haller ◽  
Rainer H. Boger
Keyword(s):  
Asymmetric Dimethylarginine ◽  
Atherosclerotic Disease ◽  
Dialysis Treatment ◽  
Relationship Of

The progression of coronary atherosclerotic disease as assessed by cine-coronary arteriography

1973 ◽  
Vol 86 (2) ◽  
pp. 165-172 ◽  
Author(s):  
Robert R. Henderson ◽  
George G. Rowe
Keyword(s):  
Coronary Arteriography ◽  
Atherosclerotic Disease
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