Utility of phrenic nerve conduction studies for identification of patients with neuromuscular diseases requiring invasive mechanical ventilation

Abstract Background Cervical spondylosis is a chronic degenerative condition of the cervical spine that can affect the cervical nerve roots. The origin of the phrenic nerve makes it vulnerable to injury. The purpose of this study is to investigate possible subtle phrenic nerve affection in patients with cervical spondylosis using nerve conduction studies (NCS). This study was conducted on 30 patients with cervical spondylosis above C5 and on 30 healthy volunteers. Nerve conduction studies of both phrenic nerves were performed in all cases. Results The patients with cervical spondylosis showed a statistically highly significant prolongation of phrenic nerve distal motor latency (DML) than the control group (P < 0.01). There was no significant difference regarding amplitude (P > 0.05). There was a significant correlation between DML and X-ray score (r < 0.05). Conclusions Cervical spondylosis is an underestimated cause of phrenic nerve delayed DML. There is a correlation between the delay of phrenic nerve DML and the severity of cervical spondylosis.

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Spinal cord injury level and Phrenic Nerve Conduction Studies do not predict diaphragm pacing success or failure- all patients should undergo diagnostic laparoscopy

The American Journal of Surgery ◽

10.1016/j.amjsurg.2020.11.042 ◽

2020 ◽

Author(s):

Raymond P. Onders ◽

MaryJo Elmo ◽

Cindy Stepien ◽

Bashar Katirji

Keyword(s):

Spinal Cord ◽

Spinal Cord Injury ◽

Phrenic Nerve ◽

Nerve Conduction ◽

Diagnostic Laparoscopy ◽

Nerve Conduction Studies ◽

Diaphragm Pacing ◽

Cord Injury

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Phrenic nerve conduction studies: Technical aspects and normative data

Muscle & Nerve ◽

10.1002/mus.20887 ◽

2007 ◽

Cited By ~ 1

Author(s):

Anita Resman-G??spěrsč ◽

Simon Podnar

Keyword(s):

Phrenic Nerve ◽

Nerve Conduction ◽

Normative Data ◽

Nerve Conduction Studies ◽

Technical Aspects

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32. Phrenic nerve conduction studies in patients with chronic obstructive pulmonary disease

Clinical Neurophysiology ◽

10.1016/j.clinph.2011.11.115 ◽

2012 ◽

Vol 123 (6) ◽

pp. e26

Author(s):

S. Podnar ◽

M. Harlander

Keyword(s):

Chronic Obstructive Pulmonary Disease ◽

Pulmonary Disease ◽

Phrenic Nerve ◽

Nerve Conduction ◽

Nerve Conduction Studies ◽

Chronic Obstructive ◽

Obstructive Pulmonary Disease

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Phrenic nerve conduction studies: normative data and technical aspects

Arquivos de Neuro-Psiquiatria ◽

10.1590/0004-282x20170153 ◽

2017 ◽

Vol 75 (12) ◽

pp. 869-874 ◽

Cited By ~ 2

Author(s):

Analucia Abreu Maranhão ◽

Sonia Regina da Silva Carvalho ◽

Marcelo Ribeiro Caetano ◽

Alexandre Hofke Alamy ◽

Eduardo Mesquita Peixoto ◽

...

Keyword(s):

Phrenic Nerve ◽

Nerve Conduction ◽

Normative Data ◽

Compound Muscle Action Potential ◽

Nerve Conduction Studies ◽

Healthy Population ◽

Lateral Border ◽

Nerve Response ◽

Muscle Action Potential ◽

Stimulation Of

ABSTRACT Objective: The aim of the present study was to define normative data of phrenic nerve conduction parameters of a healthy population. Methods: Phrenic nerve conduction studies were performed in 27 healthy volunteers. Results: The normative limits for expiratory phrenic nerve compound muscle action potential were: amplitude (0.47 mv - 0.83 mv), latency (5.74 ms - 7.10 ms), area (6.20 ms/mv - 7.20 ms/mv) and duration (18.30 ms - 20.96 ms). Inspiratory normative limits were: amplitude (0.67 mv - 1.11 mv), latency (5.90 ms - 6.34 ms), area (5.62 ms/mv - 6.72 ms/mv) and duration (13.77 ms - 15.37 ms). Conclusion: The best point of phrenic nerve stimulus in the neck varies among individuals between the medial and lateral border of the clavicular head of the sternocleidomastoid muscle and stimulation of both sites, then choosing the best phrenic nerve response, seems to be the appropriate procedure.

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