The Effect of Occupation-based Cognitive Rehabilitation for Traumatic Brain Injury: A Meta-analysis of Randomized Controlled Trials

2015 ◽  
Vol 22 (2) ◽  
pp. 104-116 ◽  
Author(s):  
Hae Yean Park ◽  
Kinsuk Maitra ◽  
Kristina Marie Martinez
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Randomized Controlled Trials ◽  
Cognitive Rehabilitation ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Randomized Controlled

Efficacy of Progesterone for Acute Traumatic Brain Injury: a Meta-analysis of Randomized Controlled Trials

2015 ◽  
Vol 53 (10) ◽  
pp. 7070-7077 ◽  
Author(s):  
Zhen Wang ◽  
LiGen Shi ◽  
Wu Ding ◽  
FangJie Shao ◽  
Jun Yu ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Randomized Controlled Trials ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Randomized Controlled ◽  
Acute Traumatic Brain Injury

Role of Decompressive Craniectomy in Traumatic Brain Injury – A Meta-analysis of Randomized Controlled Trials

2019 ◽  
Vol 67 (5) ◽  
pp. 1225 ◽  
Author(s):  
Kanwaljeet Garg ◽  
PreetM Singh ◽  
Raghav Singla ◽  
Ankita Aggarwal ◽  
Anuradha Borle ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Randomized Controlled Trials ◽  
Decompressive Craniectomy ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Randomized Controlled

scholarly journals Hypertonic saline in severe traumatic brain injury: a systematic review and meta-analysis of randomized controlled trials – ERRATUM

CJEM ◽  
2016 ◽  
Vol 18 (3) ◽  
pp. 243-243 ◽  
Author(s):  
Elyse Berger-Pelletier ◽  
Marcel Émond ◽  
François Lauzier ◽  
Jean-François Shields ◽  
Alexis F. Turgeon
Keyword(s):  
Systematic Review ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Randomized Controlled Trials ◽  
Hypertonic Saline ◽  
Severe Traumatic Brain Injury ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Randomized Controlled

scholarly journals Place of tranexamic acid in traumatic brain injury: a systematic review and meta-analysis of randomized controlled trials

2021 ◽  
Vol 6 (4) ◽  
pp. 155-163
Author(s):  
Mahdi Al-Jeabory ◽  
Lukasz Szarpak ◽  
Zubaid Rafique ◽  
Nilesh R. Vasan ◽  
Kecskes Attila ◽  
...  
Keyword(s):  
Systematic Review ◽  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Tranexamic Acid ◽  
Randomized Controlled Trials ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Randomized Controlled

scholarly journals Efficacy and safety of erythropoietin for traumatic brain injury: a meta-analysis of randomized controlled trials

2020 ◽  
Author(s):  
Motao Liu ◽  
Amy J. Wang ◽  
Yu Chen ◽  
Gexin Zhao ◽  
Zhifeng Jiang ◽  
...  
Keyword(s):  
Traumatic Brain Injury ◽  
Brain Injury ◽  
Adverse Effects ◽  
Adverse Events ◽  
Hospital Mortality ◽  
Randomized Controlled Trials ◽  
Meta Analysis ◽  
Controlled Trials ◽  
Randomized Controlled

Abstract Background Recent studies regarding the effects of erythropoietin (EPO) for treating traumatic brain injury (TBI) have been inconsistent. This study conducts a meta-analysis of randomized controlled trials (RCTs) to assess the safety and efficacy of EPO for TBI patients at various follow-up time points. Methods A literature search was performed using PubMed, Web of Science, MEDLINE, Embase, Google Scholar and the Cochrane Library for RCTs studying EPO in TBI patients published through March 2019. Non-English manuscripts and non-human studies were excluded. The assessed outcomes include mortality, neurological recovery and associated adverse effects. Dichotomous variables are presented as risk ratios (RR) with a 95% confidence interval (CI). Results A total of seven RCTs involving 1197 TBI patients were included in this study. Compared to the placebo arm, treatment with EPO did not improve acute hospital mortality or short-term mortality. However, there was a significant improvement in mid-term (6 months) follow-up survival rates. EPO administration was not associated with neurological function improvement. Regarding adverse effects, EPO treatment did not increase the incidence of thromboembolic events or other associated adverse events.Conclusions This meta-analysis indicates a slight mortality benefit for TBI patients treated with EPO at mid-term follow-up. EPO does not improve in-hospital mortality, nor does it increase adverse events including thrombotic, cardiovascular and other associated complications. Our analysis did not demonstrate a significant beneficial effect of EPO intervention on the recovery of neurological function. Future RCTs are required to further characterize the use of EPO in TBI.

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