INTERNAL AND EXTERNAL VALIDITY OF THE COMPARATIVE INTERRUPTED TIME‐SERIES DESIGN: A META‐ANALYSIS

Author(s):  
Jared Coopersmith ◽  
Thomas D. Cook ◽  
Jelena Zurovac ◽  
Duncan Chaplin ◽  
Lauren V. Forrow
2019 ◽  
Vol 19 (1) ◽  
Author(s):  
Jayna Holroyd-Leduc ◽  
◽  
Charmalee Harris ◽  
Jemila S. Hamid ◽  
Joycelyne E. Ewusie ◽  
...  

Abstract Background As the population ages, older hospitalized patients are at increased risk for hospital-acquired morbidity. The Mobilization of Vulnerable Elders (MOVE) program is an evidence-informed early mobilization intervention that was previously evaluated in Ontario, Canada. The program was effective at improving mobilization rates and decreasing length of stay in academic hospitals. The aim of this study was to scale-up the program and conduct a replication study evaluating the impact of the evidence-informed mobilization intervention on various units in community hospitals within a different Canadian province. Methods The MOVE program was tailored to the local context at four community hospitals in Alberta, Canada. The study population was patients aged 65 years and older who were admitted to medicine, surgery, rehabilitation and intensive care units between July 2015 and July 2016. The primary outcome was patient mobilization measured by conducting visual audits twice a week, three times a day. The secondary outcomes included hospital length of stay obtained from hospital administrative data, and perceptions of the intervention assessed through a qualitative assessment. Using an interrupted time series design, the intervention was evaluated over three time periods (pre-intervention, during, and post-intervention). Results A total of 3601 patients [mean age 80.1 years (SD = 8.4 years)] were included in the overall analysis. There was a significant increase in mobilization at the end of the intervention period compared to pre-intervention, with 6% more patients out of bed (95% confidence interval (CI) 1, 11; p-value = 0.0173). A decreasing trend in median length of stay was observed, where patients on average stayed an estimated 3.59 fewer days (95%CI -15.06, 7.88) during the intervention compared to pre-intervention period. Conclusions MOVE is a low-cost, effective and adaptable intervention that improves mobilization in older hospitalized patients. This intervention has been replicated and scaled up across various units and hospital settings.


2018 ◽  
Vol 5 (1) ◽  
Author(s):  
Svetla Slavova ◽  
Julia F. Costich ◽  
Huong Luu ◽  
Judith Fields ◽  
Barbara A. Gabella ◽  
...  

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