Low dose sirolimus treatment for refractory tufted angioma and congenital kaposiform hemangioendothelioma, both with Kasabach‐Merritt phenomenon

2019 ◽  
Vol 66 (8) ◽  
Author(s):  
Letícia G. Mariani ◽  
Ismael R. Schmitt ◽  
Clotilde D. Garcia ◽  
Ana E. Kiszewski
Keyword(s):  
Low Dose ◽  
Kaposiform Hemangioendothelioma ◽  
Tufted Angioma

Comparison of Corticosteroid and Vincristine in Treating Kaposiform Hemangioendothelioma and Tufted Angioma: A Systematic Review and Meta-Analysis

2018 ◽  
Vol 29 (05) ◽  
pp. 401-407 ◽  
Author(s):  
Wei Yao ◽  
Kai Li ◽  
Zuopeng Wang ◽  
Jiahao Pei ◽  
Xiangqi Liu ◽  
...  
Keyword(s):  
Recurrence Rate ◽  
Adverse Reactions ◽  
Meta Analysis ◽  
Case Series ◽  
Research Quality ◽  
Cochrane Library ◽  
Kaposiform Hemangioendothelioma ◽  
Systemic Corticosteroids ◽  
Tufted Angioma

Objective To evaluate the outcome and safety of corticosteroids and vincristine (VCR) in the treatment of kaposiform hemangioendothelioma (KHE) and tufted angioma (TA). Materials and Methods Clinical studies involving corticosteroids and VCR therapies in treating KHE/TA were identified by using PubMed, Cochrane Library, OVID, EBSCO, CNKI, VIP, and Wanfang databases from their establishment date to December 2017. Randomized controlled trials, case–control, or case series with more than five cases were included. The following data were extracted: study sample, demographics, responses rate, recurrence rate, and adverse reactions. Two reviewers completed screening and extraction. Methodological quality was evaluated with quality appraisal tool. Results A total of 266 studies were found, and 27 studies were finally included in this research; quality of all studies was low. Seven studies with a total of 123 participants, which compared the effect of systemic corticosteroids with that of VCR, were performed for the meta-analysis. The results indicated that the effect of VCR was significantly higher than that of corticosteroids (relative risk [RR] = 2.08, 95% confidence interval [CI]: 1.38–3.16). The recurrence rate of VCR (11.1%) was lower than that of corticosteroids (50%), but there was no statistical difference between the two therapies (p = 0.1312). The result of pooled adverse reactions response rate for VCR was 18.2%, significantly lower than that for corticosteroids, which was 52.0%. Conclusion The present profile shows that VCR is relatively more effective and safer in treating KHE/TA than corticosteroids are. So, we believe VCR could be used as a first-line medication agent in the treatment of KHE/TA.

Ultrasonography and magnetic resonance imaging features of kaposiform hemangioendothelioma and tufted angioma

2019 ◽  
Vol 46 (10) ◽  
pp. 835-842 ◽  
Author(s):  
Xia Gong ◽  
Hanru Ying ◽  
Zimin Zhang ◽  
Lizhen Wang ◽  
Jia Li ◽  
...  
Keyword(s):  
Magnetic Resonance Imaging ◽  
Magnetic Resonance ◽  
Imaging Features ◽  
Resonance Imaging ◽  
Kaposiform Hemangioendothelioma ◽  
Tufted Angioma

Tacrolimus ointment for the treatment of superficial kaposiform hemangioendothelioma and tufted angioma

2019 ◽  
Vol 46 (10) ◽  
pp. 898-901 ◽  
Author(s):  
Xuepeng Zhang ◽  
Kaiying Yang ◽  
Siyuan Chen ◽  
Yi Ji
Keyword(s):  
Kaposiform Hemangioendothelioma ◽  
Tacrolimus Ointment ◽  
Tufted Angioma

An intermediate vascular tumour between kaposiform hemangioendothelioma and tufted angioma with regression of the skin lesion

2017 ◽  
Vol 27 (2) ◽  
pp. 175-176 ◽  
Author(s):  
Teruhiko Makino ◽  
Waka Ishida ◽  
Takeru Hamashima ◽  
Megumi Mizawa ◽  
Masakiyo Sasahara ◽  
...  
Keyword(s):  
Skin Lesion ◽  
Vascular Tumour ◽  
Kaposiform Hemangioendothelioma ◽  
Tufted Angioma

Transformation between Kaposiform Hemangioendothelioma and Tufted Angioma

Dermatology ◽  
2003 ◽  
Vol 206 (4) ◽  
pp. 334-337 ◽  
Author(s):  
Chia-Yu Chu ◽  
Cheng-Hsiang Hsiao ◽  
Hsien-Ching Chiu
Keyword(s):  
Kaposiform Hemangioendothelioma ◽  
Tufted Angioma

scholarly journals Clinical Outcomes for Systemic Corticosteroids Versus Vincristine in Treating Kaposiform Hemangioendothelioma and Tufted Angioma

Medicine ◽  
2016 ◽  
Vol 95 (20) ◽  
pp. e3431 ◽  
Author(s):  
Xiaohan Liu ◽  
Jiaying Li ◽  
Xinhua Qu ◽  
Weili Yan ◽  
Ling Zhang ◽  
...  
Keyword(s):  
Clinical Outcomes ◽  
Kaposiform Hemangioendothelioma ◽  
Systemic Corticosteroids ◽  
Tufted Angioma

scholarly journals Kaposiform hemangioendothelioma and tufted angioma – (epi)genetic analysis including genome-wide methylation profiling

2020 ◽  
Vol 44 ◽  
pp. 151434 ◽  
Author(s):  
Roel W. Ten Broek ◽  
Christian Koelsche ◽  
Astrid Eijkelenboom ◽  
Thomas Mentzel ◽  
David Creytens ◽  
...  
Keyword(s):  
Genetic Analysis ◽  
Kaposiform Hemangioendothelioma ◽  
Genome Wide ◽  
Tufted Angioma ◽  
Methylation Profiling

Expression of Prox1, Lymphatic Endothelial Nuclear Transcription Factor, in Kaposiform Hemangioendothelioma and Tufted Angioma

2010 ◽  
pp. 1 ◽  
Author(s):  
Aude Rimella Le Huu ◽  
Chris H. Jokinen ◽  
Brian P. Ruben ◽  
Martin C. Mihm ◽  
Sharon W. Weiss ◽  
...  
Keyword(s):  
Transcription Factor ◽  
Kaposiform Hemangioendothelioma ◽  
Nuclear Transcription Factor ◽  
Tufted Angioma
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