A rare case of uterine myxoid leiomyosarcoma

Myxoid leiomyosarcoma is an uncommon tumour and in most cases, it is recognised only after the surgery. A 65 years old female patient got admitted at our hospital with history of rapidly growing abdominal mass with pain in abdomen since last 3 months. During abdominal examination 32 weeks huge mass was noted and on prevaginal examination mass couldn’t be separated from uterus. LDH was elevated, USG suggestive of vascular tumour of with neoplastic etiology of ovarain origin. CECT was done and findings suggestive of uterine adenocarcinoma with peritoneal carcinomatosis. Exploratory laparotomy with total abdominal hysterectomy with bilateral salphingoopherectomy with omentectomy with debulking surgery was performed. HPR reports suggestive of myxoid leiomyosarcoma with mitotic index of 10 with tumour cell necrosis suggestive of poor prognosis. Post-operative period patient had developed sudden myocardial infarction and shifted to ICU where she died due to ventricular fibrillation.

Conjunctival granulomatous capillary haemangioma in children: case report and review of the literature

Background Granulomatous capillary haemangioma refers to a benign vascular tumour that commonly affects the skin, with occasional involvement of the mucosa. Reports of conjunctival granulomatous capillary haemangioma in children are uncommon. In this article, we present a case of granulomatous capillary haemangioma and a brief review of the relevant literature. Case presentation An 11-year-old girl presented with a conjunctival mass. An excision of the entire lesion was performed. Histopathology showed a granulomatous capillary haemangioma. Conclusions The clinical manifestations of granulomatous capillary haemangioma lack specificity; pathological characteristics and immunohistochemistry are the main basis for diagnosis. We retrospectively analysed the diagnosis and treatment of a patient with conjunctival granulomatous capillary haemangioma to deepen the understanding and facilitate the diagnosis and treatment of this disease.

HEMANGIOPERICYTOMA OF PALATE A RARE CASE REPORT

The Hemangiopericytoma is a rare vascular tumour originating from the pericytes, which are found on the external surface of the capillaries and are thought to act as a sphincter that controls blood flow. It has a high propensity for recurrence and metastasis.The tumor usually develops as a slowly enlarging painless mass.It typically occurs in the soft tissues of the extremities and trunk, and is rarely seen in the oral cavity.15–16% are seen in the head and neck region.The most common sites of involvement are scalp, face, neck, nasal cavities and paranasal sinuses. Involvement of the palate is extremely rare and so here weare presenting a case of hemangiopericytoma of palate, its diagnosis, management and a brief review of literature.

Multifocal cutaneous epithelioid hemangiodothelioma on the same lower limb

<p class="abstract">Epithelioid hemangioendothelioma (EHE) is a rare low-grade vascular tumour mainly affecting bones, deep soft tissues and exceptionally the skin. Multifocal cutaneous involvement is uncommon and should raise suspicion for metastasizing extracutaneous epithelioid hemangiodothelioma. Hereby we report the case of a young patient with multifocal cutaneous EHE involving the same lower limb. We emphasize the necessity for dermatologists to evoke the diagnosis of EHE in patients presenting with nonspecific tumours of the extremities. Prompt management and diagnosis are essential in this potential aggressive tumour.</p>

Pyogenic granuloma of the scrotum after treatment of a condyloma with tricholoroacetic acid

Pyogenic granuloma (PG) – also known as lobular capillary hemangioma – is a benign vascular tumour that occurs on the skin and mucous membranes. Genital warts—also known as condylomata acuminata—are raised lesions that develop on the skin and mucous membranes after infection with some types of human papillomavirus (HPV). Trichloroacetic acid is very often used, given the availability of the product and its low price. We report an original case of pyogenic granuloma, by its etiology and location. A 33-year-old patient developed a pyogenic granuloma on the scrotum following treatment of a condyloma with trichloroacetic acid. To the best of our knowledge, it’s the first case of PG secondary to the application of trichloroacetic acid for the treatment of a scrotal condyloma published in the literature.

Sclerosing angiomatoid nodular transformation of spleen: an uncommon benign lesion of spleen

SANT (sclerosing angiomatoid nodular transformation) is a rare benign vascular tumour of spleen. SANT can mimic benign and malignant conditions of spleen. There are no definite radiological features. It has characteristic histopathology and immunohistochemistry findings which help us to differentiate it from other angiomatoid and tumor-like lesions. Splenectomy is the treatment of choice as it is diagnostic and therapeutic at the same time. We present a case of 22 years female with left upper quadrant pain since, 2 months. Magnetic Resonance Imaging revealed well-defined hypodense mass measuring 6.3×6.1×5.8cm in the spleen, with provisional diagnosis of hemangioma. Laproscopic splenectomy was done and a diagnosis of SANT was made on histology and immunohistochemistry. This case shows us that SANT should be considered in the differential diagnosis of splenic solid lesions.

Haemangioma Successfully Treated in a Bitch with Mercurius solubilis: A Case Report

Conventional medical therapy for haemangioma usually consists of corticosteroids through oral administration, intralesional injection or topical application. Recently, propranolol has demonstrated to offer advantages because its therapeutic efficacy is comparable and fewer adverse effects are observed. This benign vascular tumour is not always so complicated to have to be removed surgically and many others remit without treatment. However, sometimes the unexpected can happen and evolve unfavourably. For these situations, homeopathy can also be evaluated. Here is a case report of an elderly bitch that developed a haemangioma on the pad of the left fifth toe. The lesion increased in size after applying a corticosteroid ointment and became an infected wound with suppuration when the bitch bit it (self-mutilation). A homeopathic approach to the treatment was proposed. Complete remission of the vascular tumour and improvement of behavioural and physical complaints was achieved with a high dilution of Mercurius solubilis. The homeopathic remedy Phosphorus, a phytotherapic ointment of Calendula officinalis, and the application of topical antibiotics did not have the efficacy of the previous one. Although homeopathy does not yet have a specific mechanism of action for each remedy, the pathogenesis of M. solubilis is compatible with a negative regulation of glutamine synthetase. Given that it has been shown that ultra-dilutions can stimulate gene expression, it is theoretically hypothesised here that Mercurius could stimulate glutamate-ammonia ligase gene, which expresses the aforementioned enzyme, and solve or improve diseases whose symptoms are due to their underexpression or inhibition (at gene and protein level). Hence, the aim of this article is to show the results of homeopathy in the clinical practice and to propose a line of research on the mechanism of action of the remedies.

LITTORAL CELL ANGIOMA OF SPLEEN - A RARE CASE REPORT

INTRODUCTION Littoral- cell angioma (LCA) is a rare benign vascular tumour of the spleen. There have been less then 250 cases reported in the literature. Recent reports have described it to be a Benign lesion with congenital and immunologic associations. We report a case of LCA of the spleen. PRESENTATION OF CASE A 09 -year-old male patient was admitted to hospital with a one month duration of intermittent upper abdominal pain and nausea. Imaging studies, including Ultrasonography and Colourdoppler Imaging of portal venous systems. Radiology show moderate gross enlargement-16cm & normal in echotexture with no focal lesion. Splenic vein-10mm in caliber with partial thrombus formation. An open splenectomy was performed and his post-operative recovery was uneventful. DISCUSSION Littoral cell angioma of the spleen is a benign vascular tumour that has been infrequently reported in the English literature. While it does have malignant potential, the vast majority are benign. Diagnosis depends on the expression of endothelial markers like CD31 and histiocytic markers like CD68.Malignant potential enhanced by the presence of splenomegaly as well. CONCLUSION This rare condition is made by the presence of rare vascular tumour in the spleens as well.

Capillary-Cavernous Hemangioma of Lymph Node: An Extremely Rare Case

Background: Hemangioma is a benign vascular tumour commonly found in young children. This tumor can grow within many organs, but occurring in the lymph node is extremely rare. The capillary-cavernous hemangioma (CCH) of the lymph node was mostly found as an incidental finding after histopathology confirmation of oncological surgery. Case: We presented the first case of intranodal CCH from the parietal region of the head in a 11-year-old boy. The easily-bleed lump was found above the head fascia and confirmed with histopathological examination. Conclusion: The capillary-cavernous hemangioma arising from the lymph node was an extremely rare pathological finding after oncological surgery. Treatment by surgical excision was curative. The awareness of this benign vascular tumour must be known to physicians so that it was not mistakenly diagnosed as a malignant disease with subsequent unnecessary radical therapy.

Management of an oncological wound: Diagnosis, conflicting therapies and decision-making

This article presents the case of a non-HIV-positive patient who contemporaneously suffered from Kaposi’s sarcoma and bullous pemphigoid. Kaposi’s sarcoma is a rare low-grade vascular tumour associated with human herpes virus 8 infection, while bullous pemphigoid is the most common autoimmune subepidermal blistering disease in western countries.