Juvenile myelomonocytic leukaemia presentation after preceding juvenile xanthogranuloma harbouring an identical somatic PTPN11 mutation

2020 ◽  
Vol 67 (9) ◽  
Author(s):  
Bence Bátai ◽  
Szilvia Krizsán ◽  
Ambrus Gángó ◽  
Lajos Hegyi ◽  
Monika Csóka ◽  
...  
Keyword(s):  
Juvenile Xanthogranuloma ◽  
Ptpn11 Mutation

Isolated spinal juvenile xanthogranuloma in an infant presenting as acute paraplegia

2012 ◽  
Vol 43 (02) ◽  
Author(s):  
D Wille ◽  
O Bozinov ◽  
I Scheer ◽  
M Grotzer ◽  
E Boltshauser
Keyword(s):  
Juvenile Xanthogranuloma ◽  
Acute Paraplegia

Giant Solitary Juvenile Xanthogranuloma with Spontaneous Regression

1979 ◽  
Vol 41 (2) ◽  
pp. 258-263 ◽  
Author(s):  
Tsunemi NUMATA ◽  
Schuichi INADA
Keyword(s):  
Spontaneous Regression ◽  
Juvenile Xanthogranuloma

Ulcerated Nodules in a Patient of Juvenile Xanthogranuloma.

2000 ◽  
Vol 62 (2) ◽  
pp. 172-174 ◽  
Author(s):  
Keiko KOBAYASHI ◽  
Akimichi MORITA ◽  
Noriyuki SAKAKIBARA ◽  
Takuo TSUJI
Keyword(s):  
Juvenile Xanthogranuloma

Juvenile xanthogranuloma of the subdural spaces mimicking chronic hematoma with positive FDG uptake on PET: case report

2020 ◽  
Vol 26 (4) ◽  
pp. 449-453
Author(s):  
Jacob A. Kahn ◽  
Jeffrey T. Waltz ◽  
Ramin M. Eskandari ◽  
Cynthia T. Welsh ◽  
Michael U. Antonucci
Keyword(s):  
Potential Role ◽  
Response To Treatment ◽  
Juvenile Xanthogranuloma ◽  
Imaging Features ◽  
Limited Information ◽  
Advanced Imaging ◽  
Systemic Involvement ◽  
The Central Nervous System ◽  
Infancy And Early Childhood

The authors report an unusual presentation of juvenile xanthogranuloma (JXG), a non–Langerhans cell histiocytosis of infancy and early childhood. This entity typically presents as a cutaneous head or neck nodule but can manifest with more systemic involvement including in the central nervous system. However, currently there is limited information regarding specific imaging features differentiating JXG from other neuropathological entities, with diagnosis typically made only after tissue sampling. The authors reviewed the initial images of a young patient with shunt-treated hydrocephalus and enlarging, chronic, extraaxial processes presumed to reflect subdural collections from overshunting, and they examine the operative discovery of a mass lesion that was pathologically proven to be JXG. Their results incorporate the important associated histological and advanced imaging features, including previously unreported metabolic activity on FDG PET. Ultimately, the case underscores the need to consider JXG in differential diagnoses of pediatric intracranial masses and highlights the potential role of PET in the initial diagnosis and response to treatment.

Juvenile Xanthogranuloma of the Sellar Region with a 5-Year Medical History: Case Report and Literature Review

2021 ◽  
pp. 1-8
Author(s):  
Dekui Cheng ◽  
Fengyu Yang ◽  
Ziji Li ◽  
Fan Qv ◽  
Wei Liu
Keyword(s):  
Medical History ◽  
Pediatric Population ◽  
Benign Lesion ◽  
Giant Cells ◽  
Juvenile Xanthogranuloma ◽  
Epithelial Tissue ◽  
Sellar Region ◽  
Optic Chiasma ◽  
Suprasellar Region ◽  
Field Disturbance

<b><i>Introduction:</i></b> Xanthogranuloma of the sellar region is a rare benign lesion, and there are few cases reported in children. Its histogenesis is controversial, and it is difficult to strictly differentiate it from craniopharyngioma (CP), Rathke’s cleft cyst, or pituitary adenoma. <b><i>Case Presentation:</i></b> A 16-year-old boy presented with a rare xanthogranuloma of the sellar region after complaining of retardation of growth 5 years previously. The ophthalmologic evaluation revealed no visual field disturbance. Endocrinological examination revealed hypopituitarism. Magnetic resonance imaging showed an intrasellar mass extending into the suprasellar region and compressing the optic chiasma, which appeared mixed signals on T1-weighted images. Endonasal transsphenoidal resection of the tumor was performed. Histological analysis of the tumor sections demonstrated granulomatous tissue with cholesterol clefts, hemosiderin deposits, fibrous tissues, multinucleated giant cells, and lymphocyte. Thus, the tumor was pathologically diagnosed as xanthogranuloma of the sellar region, which is different from adamantinomatous CP. There was no epithelial tissue in any part of the tumor including tumor capsule but have focal necrosis and calcification. His endocrinological dysfunction did not recover, so a hormonal replacement was continuously required. <b><i>Conclusion:</i></b> Xanthogranuloma of the sellar region is a rare entity but must be considered in the differential diagnosis of lesions of the sellar region, even in pediatric population. We should think about this disease when dealing with children with stunted growth accompanied by a long medical history. Our case demonstrates the natural progression of the disease, suggesting that xanthogranuloma of the sellar region without epithelial components may be an independent disease.

18476 Scattered yellow papules in a pediatric patient: Diagnostic importance of distinguishing juvenile xanthogranuloma from xanthelasmoid mastocytosis

2020 ◽  
Vol 83 (6) ◽  
pp. AB213
Author(s):  
Yizhen E. Liu ◽  
Eddie A. Kwan ◽  
Matthew M. Malan ◽  
Wendi E. Wohltmann
Keyword(s):  
Pediatric Patient ◽  
Juvenile Xanthogranuloma ◽  
Diagnostic Importance

Intracranial juvenile xanthogranuloma in an infant

2021 ◽  
Author(s):  
Ho-Sung Myeong ◽  
Eun Jung Koh ◽  
Jung-Eun Cheon ◽  
Sung-Hye Park ◽  
Seung-Ki Kim
Keyword(s):  
Juvenile Xanthogranuloma

Ulcerated juvenile xanthogranuloma of the scalp

2003 ◽  
Vol 44 (1) ◽  
pp. 74-75 ◽  
Author(s):  
Karen Behne ◽  
Terrence Casey
Keyword(s):  
Juvenile Xanthogranuloma
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