scholarly journals Electron transfer dissociation (ETD): The mass spectrometric breakthrough essential for O -GlcNAc protein site assignments-a study of the O -GlcNAcylated protein Host Cell Factor C1

PROTEOMICS ◽  
2013 ◽  
Vol 13 (6) ◽  
pp. 982-991 ◽  
Author(s):  
Samuel A. Myers ◽  
Salima Daou ◽  
El Bachir Affar ◽  
Al Burlingame
Keyword(s):  
Electron Transfer ◽  
Host Cell ◽  
Electron Transfer Dissociation ◽  
Mass Spectrometric ◽  
Host Cell Factor

Exploration of doubtful cases of leucine and isoleucine discrimination in mass spectrometric peptide sequencing by electron-transfer and higher-energy collision dissociation-based method

2017 ◽  
Vol 23 (6) ◽  
pp. 376-384 ◽  
Author(s):  
Sergey V Kovalyov ◽  
Sergey S Zhokhov ◽  
Ludmila V Onoprienko ◽  
Boris V Vaskovsky ◽  
Albert T Lebedev
Keyword(s):  
Electron Transfer ◽  
Electron Transfer Dissociation ◽  
Protonated Peptide ◽  
Peptide Sequencing ◽  
Mass Spectrometric ◽  
Energy Collision ◽  
Tryptic Peptides ◽  
Radical Site ◽  
Peptide Molecule ◽  
Sequencing Process

Electron-transfer dissociation (ETD) and electron-transfer and higher-energy collision dissociation (EThcD) spectra of short tryptic peptides with leucine/isoleucine residues in neighboring positions demonstrate intensive w-ions. On the contrary, u-ions possess very low intensities (if present at all). Therefore radical site migration is negligible in the applied conditions while ETD (EThcD) spectra allow for the reliable discrimination of the isomeric residues in the sequencing process. The presence of a fragment ion 43.055 mass units lower than z2-ion of peptides with IK sequence at their C-termini was shown to be a result of alternative fragmentation starting from the loss of propylammonium ion from the doubly protonated peptide molecule and formation of an oxazole fragment ion.

scholarly journals Application of electron transfer dissociation mass spectrometry in analyses of non-enzymatically glycated peptides

2007 ◽  
Vol 21 (5) ◽  
pp. 661-666 ◽  
Author(s):  
Qibin Zhang ◽  
Andrej Frolov ◽  
Ning Tang ◽  
Ralf Hoffmann ◽  
Tom van de Goor ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Electron Transfer ◽  
Electron Transfer Dissociation

scholarly journals Trans-Proteomic Pipeline supports and improves analysis of electron transfer dissociation data sets

PROTEOMICS ◽  
2010 ◽  
Vol 10 (6) ◽  
pp. 1190-1195 ◽  
Author(s):  
Eric W. Deutsch ◽  
David Shteynberg ◽  
Henry Lam ◽  
Zhi Sun ◽  
Jimmy K. Eng ◽  
...  
Keyword(s):  
Electron Transfer ◽  
Electron Transfer Dissociation ◽  
Data Sets

scholarly journals Crosstalk between O-GlcNAcylation and proteolytic cleavage regulates the host cell factor-1 maturation pathway

2011 ◽  
Vol 108 (7) ◽  
pp. 2747-2752 ◽  
Author(s):  
S. Daou ◽  
N. Mashtalir ◽  
I. Hammond-Martel ◽  
H. Pak ◽  
H. Yu ◽  
...  
Keyword(s):  
Host Cell ◽  
Proteolytic Cleavage ◽  
Host Cell Factor ◽  
Host Cell Factor 1
Sign in / Sign up

Export Citation Format

Share Document