scholarly journals Long‐term course of bronchial inflammation and pulmonary function testing in children with post‐infectious bronchiolitis obliterans

2021 ◽  
Author(s):  
Silvija Pera Jerkic ◽  
Sinem Koc‐Günel ◽  
Eva Herrmann ◽  
Lia Kriszeleit ◽  
Jonas Eckrich ◽  
...  



2002 ◽  
Vol 26 (4) ◽  
pp. 564-572 ◽  
Author(s):  
Michael B. Gotway ◽  
Jeffrey A. Golden ◽  
Jeanne M. LaBerge ◽  
W. Richard Webb ◽  
Gautham P. Reddy ◽  
...  


2018 ◽  
Vol 143 (08) ◽  
pp. 593-596 ◽  
Author(s):  
Wolfram Windisch ◽  
Carl Criée

AbstractPulmonary function testing is essential for diagnosis and treatment-guidance of chronic obstructive pulmonary disease (COPD). Airway obstruction as assessed by spirometry should follow the reference-values provided by the Global Lung Initiative (GLI) of the European Respiratory Society (ERS). In addition, lung function testing should also include the assessment of lung hyperinflation and pulmonary emphysema by full-body plethysmography and determination of diffusion capacity. This is important since both, lung hyperinflation and pulmonary emphysema, can present without existing airway obstruction. Even though this formally excludes the diagnosis of COPD, these entities still belong to this disease complex. However, strictly speaking, pharmaceutical treatment is valid only for those patients with co-existing airway obstruction according to Global Lung Initiative for Chronic Obstructive Lung Disease (GOLD) criteria – since the absence of airway obstruction serves as exclusion criterion in nearly all randomized controlled trials. Nevertheless, progressive symptoms still require detailed pulmonary function testing for the guidance of non-pharmaceutical treatment – such as endoscopic or surgical lung volume reduction, long-term oxygen therapy, long-term non-invasive ventilation, and lung transplantation.





2018 ◽  
Vol 28 (11) ◽  
pp. 897-909 ◽  
Author(s):  
Craig M. McDonald ◽  
Heather Gordish-Dressman ◽  
Erik K. Henricson ◽  
Tina Duong ◽  
Nanette C. Joyce ◽  
...  


Author(s):  
J Sulc ◽  
J Radvanska ◽  
J Radvansky ◽  
K Slaby ◽  
M Safarova ◽  
...  


2000 ◽  
Vol 16 (4) ◽  
pp. 731 ◽  
Author(s):  
U. Frey ◽  
J. Stocks ◽  
A Coates ◽  
P Sly ◽  
J Bates ◽  
...  


Author(s):  
Mathias Poussel ◽  
Isabelle Thaon ◽  
Emmanuelle Penven ◽  
Angelica I. Tiotiu

Work-related asthma (WRA) is a very frequent condition in the occupational setting, and refers either to asthma induced (occupational asthma, OA) or worsened (work-exacerbated asthma, WEA) by exposure to allergens (or other sensitizing agents) or to irritant agents at work. Diagnosis of WRA is frequently missed and should take into account clinical features and objective evaluation of lung function. The aim of this overview on pulmonary function testing in the field of WRA is to summarize the different available tests that should be considered in order to accurately diagnose WRA. When WRA is suspected, initial assessment should be carried out with spirometry and bronchodilator responsiveness testing coupled with first-step bronchial provocation testing to assess non-specific bronchial hyper-responsiveness (NSBHR). Further investigations should then refer to specialists with specific functional respiratory tests aiming to consolidate WRA diagnosis and helping to differentiate OA from WEA. Serial peak expiratory flow (PEF) with calculation of the occupation asthma system (OASYS) score as well as serial NSBHR challenge during the working period compared to the off work period are highly informative in the management of WRA. Finally, specific inhalation challenge (SIC) is considered as the reference standard and represents the best way to confirm the specific cause of WRA. Overall, clinicians should be aware that all pulmonary function tests should be standardized in accordance with current guidelines.



Lung ◽  
2021 ◽  
Author(s):  
Ajay Sheshadri ◽  
Leendert Keus ◽  
David Blanco ◽  
Xiudong Lei ◽  
Cheryl Kellner ◽  
...  


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