scholarly journals Is gamma knife radiosurgery for skull base meningiomas with carotid artery encasement supported by efficacy and safety outcomes?

2021 ◽  
Author(s):  
Federico L. Ampil ◽  
Anthony H. Sin ◽  
Donald R. Smith
Keyword(s):  
Carotid Artery ◽  
Skull Base ◽  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Efficacy And Safety ◽  
Safety Outcomes ◽  
Skull Base Meningiomas

scholarly journals Staged Gamma Knife Radiosurgery for Large Skull Base Meningiomas

Cureus ◽  
2019 ◽  
Author(s):  
Yoshiyasu Iwai ◽  
Kazuhiro Yamanaka ◽  
Wataru Shimohonji ◽  
Kenichi Ishibashi
Keyword(s):  
Skull Base ◽  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Skull Base Meningiomas

scholarly journals Outcomes and Complications of Gamma Knife Radiosurgery for Skull Base Meningiomas

2014 ◽  
Vol 75 (06) ◽  
pp. 397-401 ◽  
Author(s):  
Shyamal Bir ◽  
Sudheer Ambekar ◽  
Tabitha Ward ◽  
Anil Nanda
Keyword(s):  
Skull Base ◽  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Skull Base Meningiomas

Gamma Knife Radiosurgery of Skull Base Meningiomas

2000 ◽  
Vol 142 (6) ◽  
pp. 647-653 ◽  
Author(s):  
M. Aichholzer ◽  
A. Bertalanffy ◽  
W. Dietrich ◽  
K. Roessler ◽  
W. Pfisterer ◽  
...  
Keyword(s):  
Skull Base ◽  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Skull Base Meningiomas

Gamma Knife Radiosurgery for Skull Base Meningiomas: Long-Term Radiologic and Clinical Outcome

2008 ◽  
Vol 72 (5) ◽  
pp. 1324-1332 ◽  
Author(s):  
Jung Ho Han ◽  
Dong Gyu Kim ◽  
Hyun-Tai Chung ◽  
Chul-Kee Park ◽  
Sun Ha Paek ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Skull Base ◽  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Skull Base Meningiomas

Long-Term Experience of Gamma Knife Radiosurgery for Benign Skull Base Meningiomas

Skull Base ◽  
2007 ◽  
Vol 17 (S 1) ◽  
Author(s):  
Wolfgang Kreil ◽  
Sandro Eustacchio ◽  
Verena Weigl ◽  
Josef Luggin ◽  
Georg Papaefthymiou ◽  
...  
Keyword(s):  
Skull Base ◽  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Skull Base Meningiomas ◽  
Long Term Experience

scholarly journals Fractionated Gamma Knife radiosurgery for skull base meningiomas: a single-institution experience

2019 ◽  
Vol 46 (6) ◽  
pp. E8 ◽  
Author(s):  
Krishna C. Joshi ◽  
Alankrita Raghavan ◽  
Baha’eddin Muhsen ◽  
Jason Hsieh ◽  
Hamid Borghei-Razavi ◽  
...  
Keyword(s):  
Skull Base ◽  
Gamma Knife ◽  
Tumor Volume ◽  
Gamma Knife Radiosurgery ◽  
Cranial Neuropathy ◽  
High Dose ◽  
Perilesional Edema ◽  
The Mean ◽  
Skull Base Meningiomas

OBJECTIVEGamma Knife radiosurgery (GKRS) has been successfully used for the treatment of intracranial meningiomas given its steep dose gradients and high-dose conformality. However, treatment of skull base meningiomas (SBMs) may pose significant risk to adjacent radiation-sensitive structures such as the cranial nerves. Fractionated GKRS (fGKRS) may decrease this risk, but until recently it has not been practical with traditional pin-based systems. This study reports the authors’ experience in treating SBMs with fGKRS, using a relocatable, noninvasive immobilization system.METHODSThe authors performed a retrospective review of all patients who underwent fGKRS for SBMs between 2013 and 2018 delivered using the Extend relocatable frame system or the Icon system. Patient demographics, pre- and post-GKRS tumor characteristics, perilesional edema, prior treatment details, and clinical symptoms were evaluated. Volumetric analysis of pre-GKRS, post-GKRS, and subsequent follow-up visits was performed.RESULTSTwenty-five patients met inclusion criteria. Nineteen patients were treated with the Icon system, and 6 patients were treated with the Extend system. The mean pre-fGKRS tumor volume was 7.62 cm3 (range 4.57–13.07 cm3). The median margin dose was 25 Gy delivered in 4 (8%) or 5 (92%) fractions. The median follow-up time was 12.4 months (range 4.7–17.4 months). Two patients (9%) experienced new-onset cranial neuropathy at the first follow-up. The mean postoperative tumor volume reduction was 15.9% with 6 patients (27%) experiencing improvement of cranial neuropathy at the first follow-up. Median first follow-up scans were obtained at 3.4 months (range 2.8–4.3 months). Three patients (12%) developed asymptomatic, mild perilesional edema by the first follow-up, which remained stable subsequently.CONCLUSIONSfGKRS with relocatable, noninvasive immobilization systems is well tolerated in patients with SBMs and demonstrated satisfactory tumor control as well as limited radiation toxicity. Future prospective studies with long-term follow-up and comparison to single-session GKRS or fractionated stereotactic radiotherapy are necessary to validate these findings and determine the efficacy of this approach in the management of SBMs.

Excellent Treatment Outcomes following Gamma Knife Radiosurgery for Skull Base Meningiomas

2011 ◽  
Vol 81 (2) ◽  
pp. S287
Author(s):  
P.D. Aridgides ◽  
A. Barz ◽  
S. Bhavsar ◽  
L. Mitchell ◽  
J.A. Bogart ◽  
...  
Keyword(s):  
Skull Base ◽  
Treatment Outcomes ◽  
Gamma Knife ◽  
Gamma Knife Radiosurgery ◽  
Skull Base Meningiomas
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