scholarly journals The selectivity of α‐adrenoceptor agonists for the human α1A, α1B, and α1D‐adrenoceptors

2021 ◽  
Vol 9 (4) ◽  
Author(s):  
Richard G. W. Proudman ◽  
Jillian G. Baker
Keyword(s):  
Adrenoceptor Agonists

ADRENOCEPTOR AGONISTS AND ANTAGONISTS 1

1972 ◽  
Vol 2 (S2) ◽  
pp. 43-48
Author(s):  
Winifred G. Nayler
Keyword(s):  
Adrenoceptor Agonists

Emerging benefits and drawbacks of α 2 ‐adrenoceptor agonists in the management of sepsis and critical illness

2021 ◽  
Author(s):  
Yugeesh R. Lankadeva ◽  
Yahya Shehabi ◽  
Adam M. Deane ◽  
Mark P. Plummer ◽  
Rinaldo Bellomo ◽  
...  
Keyword(s):  
Critical Illness ◽  
Adrenoceptor Agonists

scholarly journals Ligand- and Structure-Based Analysis of Deep Learning-Generated Potential α2a Adrenoceptor Agonists

2021 ◽  
Author(s):  
Katherine J. Schultz ◽  
Sean M. Colby ◽  
Vivian S. Lin ◽  
Aaron T. Wright ◽  
Ryan S. Renslow
Keyword(s):  
Deep Learning ◽  
Adrenoceptor Agonists

Changes in Astroglial Cell Volume after Exposure to HgCl2 or CH3HgCl

1992 ◽  
Vol 20 (2) ◽  
pp. 246-250
Author(s):  
Lars Rönnbäck ◽  
Elisabeth Hansson
Keyword(s):  
Glucose Uptake ◽  
Cell Volume ◽  
Receptor Agonist ◽  
Primary Cultures ◽  
Control Cell ◽  
Astroglial Cell ◽  
Receptor Stimulation ◽  
Adrenoceptor Agonists ◽  
Β Receptor ◽  
Induced Changes

Cell volume was determined by measuring [14C]-3- O-methyl glucose uptake in astroglial-enriched primary cultures. Control cell volume was 3.20μl/mg protein. After incubation in 10 5M HgCl2 for 60 minutes, there was a 71% increase in cell volume. This increase was partially inhibited in the presence of the α1 receptor agonist, phenylephrine, or by the α2 receptor agonist clonidine, and was completely reversible by their respective antagonists, prazosine and yohimbine. The β receptor agonist, isoproterenol, which in itself increased cell volume, and 5-hydroxytryptamine (5HT) did not affect the HgCl2-induced changes in cell volume. 10 5M CH3HgCl increased cell volume by 26% after 30 minutes of incubation. This increase was not significantly influenced by adrenoceptor agonists or 5HT. It therefore seems that mercurial-induced changes in cell volume can be regulated by astroglial receptor stimulation.

β2-adrenoceptor agonists

2003 ◽  
pp. 56-104
Author(s):  
Domenico Spina ◽  
Clive P. Page ◽  
Brian J. O'Connor
Keyword(s):  
Adrenoceptor Agonists

Pathogenesis of solute-free water retention in experimental ascitic cirrhosis: is vasopressin the only culprit?

2015 ◽  
Vol 130 (2) ◽  
pp. 117-124 ◽  
Author(s):  
Giovanni Sansoè ◽  
Manuela Aragno ◽  
Raffaella Mastrocola ◽  
Maurizio Parola
Keyword(s):  
Antidiuretic Hormone ◽  
Water Retention ◽  
Renal Excretion ◽  
Free Water ◽  
Experimental Cirrhosis ◽  
Advanced Cirrhosis ◽  
Adrenoceptor Agonists ◽  
Sympatholytic Agents ◽  
Dilutional Hyponatraemia

Adrenergic hyper-function reduces renal excretion of water. In advanced cirrhosis, hypersecretion of vasopressin (antidiuretic hormone or ADH) is considered the cause of dilutional hyponatraemia. We show that in experimental cirrhosis sympatholytic agents (α2A-adrenoceptor agonists) are as effective as V2 antagonists to blunt water retention.

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