Drug Dosing in Pregnant Women: Challenges and Opportunities in Using Physiologically Based Pharmacokinetic Modeling and Simulations

Modeling And Simulations ◽

Drug Dosing ◽

Physiologically Based ◽

Challenges And Opportunities

Preliminary physiologically based pharmacokinetic modeling of renally cleared drugs in Chinese pregnant women

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2243 ◽

2020 ◽

Vol 41 (6) ◽

pp. 248-267 ◽

Cited By ~ 1

Author(s):

Ling Song ◽

Zhiheng Yu ◽

Yifan Xu ◽

Xiaobei Li ◽

Xuanlin Liu ◽

...

Keyword(s):

Pregnant Women ◽

Gestation-Specific Changes in the Anatomy and Physiology of Healthy Pregnant Women: An Extended Repository of Model Parameters for Physiologically Based Pharmacokinetic Modeling in Pregnancy

10.1007/s40262-017-0539-z ◽

2017 ◽

Vol 56 (11) ◽

pp. 1303-1330 ◽

Cited By ~ 30

Author(s):

André Dallmann ◽

Ibrahim Ince ◽

Michaela Meyer ◽

Stefan Willmann ◽

Thomas Eissing ◽

...

Keyword(s):

Pregnant Women ◽

Model Parameters ◽

Anatomy And Physiology ◽

Physiologically Based ◽

In Pregnancy

Physiologically Based Pharmacokinetic Modeling to Characterize Acetaminophen Pharmacokinetics and N-Acetyl-p-Benzoquinone Imine (NAPQI) Formation in Non-Pregnant and Pregnant Women

10.1007/s40262-019-00799-5 ◽

2019 ◽

Vol 59 (1) ◽

pp. 97-110 ◽

Cited By ~ 11

Author(s):

Paola Mian ◽

John N. van den Anker ◽

Kristel van Calsteren ◽

Pieter Annaert ◽

Dick Tibboel ◽

...

Keyword(s):

Pregnant Women ◽

Benzoquinone Imine ◽

Abstract 2791: Physiologically based pharmacokinetic modeling and simulations to estimate the efficacious dose of the CEACAM6 function-blocking antibody BAY 1834942

10.1158/1538-7445.am2018-2791 ◽

2018 ◽

Author(s):

Sabine Wittemer-Rump ◽

Christoph Niederalt ◽

Joerg Willuda ◽

Mark Trautwein ◽

Merlin Luetke-Eversloh ◽

...

Keyword(s):

Modeling And Simulations ◽

Blocking Antibody ◽

Assessment of Bisphenol a Exposure in Korean Pregnant Women by Physiologically Based Pharmacokinetic Modeling

Journal of Toxicology and Environmental Health Part A ◽

10.1080/15287394.2010.511584 ◽

2010 ◽

Vol 73 (21-22) ◽

pp. 1586-1598 ◽

Cited By ~ 16

Author(s):

Beom Soo Shin ◽

Sang Wook Hwang ◽

Jürgen B. Bulitta ◽

Jong Bong Lee ◽

Seung Du Yang ◽

...

Keyword(s):

Bisphenol A ◽

Pregnant Women ◽

Dose Adjustment of Quetiapine and Aripiprazole for Pregnant Women Using Physiologically Based Pharmacokinetic Modeling and Simulation

10.1007/s40262-020-00962-3 ◽

2020 ◽

Author(s):

Liang Zheng ◽

Shiwei Tang ◽

Rui Tang ◽

Miao Xu ◽

Xuehua Jiang ◽

...

Keyword(s):

Modeling And Simulation ◽

Pregnant Women ◽

Dose Adjustment ◽

Pharmacokinetic Modeling And Simulation

Physiologically Based ◽

Physiologically Based Pharmacokinetic Modeling of Renally Cleared Drugs in Pregnant Women

10.1007/s40262-017-0538-0 ◽

2017 ◽

Vol 56 (12) ◽

pp. 1525-1541 ◽

Cited By ~ 30

Author(s):

André Dallmann ◽

Ibrahim Ince ◽

Juri Solodenko ◽

Michaela Meyer ◽

Stefan Willmann ◽

...

Keyword(s):

Pregnant Women ◽

Physiologically-based pharmacokinetic modeling of renally excreted antiretroviral drugs in pregnant women

British Journal of Clinical Pharmacology ◽

10.1111/bcp.12685 ◽

2015 ◽

Vol 80 (5) ◽

pp. 1031-1041 ◽

Cited By ~ 27

Author(s):

Maïlys De Sousa Mendes ◽

Deborah Hirt ◽

Saik Urien ◽

Elodie Valade ◽

Naïm Bouazza ◽

...

Keyword(s):

Pregnant Women ◽

Antiretroviral Drugs ◽

The Future of Physiologically Based Pharmacokinetic Modeling to Predict Drug Exposure in Pregnant Women

CPT Pharmacometrics & Systems Pharmacology ◽

10.1038/psp.2013.9 ◽

2013 ◽

Vol 2 (3) ◽

pp. 33 ◽

Cited By ~ 7

Author(s):

AA Vinks

Keyword(s):

Pregnant Women ◽

Drug Exposure ◽

Physiologically Based ◽

The Future

Physiologically-based pharmacokinetic modeling of different size polyethylene glycol-coated gold nanoparticles in mice

10.1615/ihtc16.nmt.023362 ◽

2018 ◽

Author(s):

Linjing Deng ◽

Jinping Zhao ◽

Yufeng Miao ◽

Xu Hu ◽

Qihong Deng

Keyword(s):

Gold Nanoparticles ◽

Polyethylene Glycol ◽