The Future of Physiologically Based Pharmacokinetic Modeling to Predict Drug Exposure in Pregnant Women

CPT Pharmacometrics & Systems Pharmacology ◽

10.1038/psp.2013.9 ◽

2013 ◽

Vol 2 (3) ◽

pp. 33 ◽

Author(s):

AA Vinks

Keyword(s):

Pregnant Women ◽

Drug Exposure ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

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Physiologically-Based Pharmacokinetic Modeling to Predict Changes in Drug Exposure during Pregnancy Using the Simcyp Simulator

10.26226/morressier.57d6b2b7d462b8028d88e945 ◽

2016 ◽

Author(s):

Suvarchala Kiranmai Avvari

Keyword(s):

Drug Exposure ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Exposure During Pregnancy

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Preliminary physiologically based pharmacokinetic modeling of renally cleared drugs in Chinese pregnant women

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2243 ◽

2020 ◽

Vol 41 (6) ◽

pp. 248-267 ◽

Author(s):

Ling Song ◽

Zhiheng Yu ◽

Yifan Xu ◽

Xiaobei Li ◽

Xuanlin Liu ◽

...

Keyword(s):

Pregnant Women ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Gestation-Specific Changes in the Anatomy and Physiology of Healthy Pregnant Women: An Extended Repository of Model Parameters for Physiologically Based Pharmacokinetic Modeling in Pregnancy

Clinical Pharmacokinetics ◽

10.1007/s40262-017-0539-z ◽

2017 ◽

Vol 56 (11) ◽

pp. 1303-1330 ◽

Author(s):

André Dallmann ◽

Ibrahim Ince ◽

Michaela Meyer ◽

Stefan Willmann ◽

Thomas Eissing ◽

...

Keyword(s):

Pregnant Women ◽

Pharmacokinetic Modeling ◽

Model Parameters ◽

Physiologically Based Pharmacokinetic Modeling ◽

Anatomy And Physiology ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

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Physiologically Based Pharmacokinetic Modeling to Characterize Acetaminophen Pharmacokinetics and N-Acetyl-p-Benzoquinone Imine (NAPQI) Formation in Non-Pregnant and Pregnant Women

Clinical Pharmacokinetics ◽

10.1007/s40262-019-00799-5 ◽

2019 ◽

Vol 59 (1) ◽

pp. 97-110 ◽

Author(s):

Paola Mian ◽

John N. van den Anker ◽

Kristel van Calsteren ◽

Pieter Annaert ◽

Dick Tibboel ◽

...

Keyword(s):

Pregnant Women ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Benzoquinone Imine ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Assessment of Bisphenol a Exposure in Korean Pregnant Women by Physiologically Based Pharmacokinetic Modeling

Journal of Toxicology and Environmental Health Part A ◽

10.1080/15287394.2010.511584 ◽

2010 ◽

Vol 73 (21-22) ◽

pp. 1586-1598 ◽

Author(s):

Beom Soo Shin ◽

Sang Wook Hwang ◽

Jürgen B. Bulitta ◽

Jong Bong Lee ◽

Seung Du Yang ◽

...

Keyword(s):

Bisphenol A ◽

Pregnant Women ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Application of Physiologically Based Pharmacokinetic Modeling to Predict Drug Exposure and Support Dosing Recommendations for Potential Drug‐Drug Interactions or in Special Populations: An Example Using Tofacitinib

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1679 ◽

2020 ◽

Vol 60 (12) ◽

pp. 1617-1628

Author(s):

Susanna Tse ◽

Martin E. Dowty ◽

Sujatha Menon ◽

Pankaj Gupta ◽

Sriram Krishnaswami

Keyword(s):

Drug Interactions ◽

Drug Exposure ◽

Pharmacokinetic Modeling ◽

Special Populations ◽

Potential Drug ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Dose Adjustment of Quetiapine and Aripiprazole for Pregnant Women Using Physiologically Based Pharmacokinetic Modeling and Simulation

Clinical Pharmacokinetics ◽

10.1007/s40262-020-00962-3 ◽

2020 ◽

Author(s):

Liang Zheng ◽

Shiwei Tang ◽

Rui Tang ◽

Miao Xu ◽

Xuehua Jiang ◽

...

Keyword(s):

Modeling And Simulation ◽

Pregnant Women ◽

Dose Adjustment ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Pharmacokinetic Modeling And Simulation

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Drug Dosing in Pregnant Women: Challenges and Opportunities in Using Physiologically Based Pharmacokinetic Modeling and Simulations

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12274 ◽

2018 ◽

Vol 7 (2) ◽

pp. 103-110 ◽

Author(s):

Alice Ban Ke ◽

Rick Greupink ◽

Khaled Abduljalil

Keyword(s):

Pregnant Women ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Modeling And Simulations ◽

Drug Dosing ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Challenges And Opportunities

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Physiologically Based Pharmacokinetic Modeling to Identify Physiological and Molecular Characteristics Driving Variability in Drug Exposure

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.1076 ◽

2018 ◽

Vol 104 (6) ◽

pp. 1219-1228 ◽

Author(s):

Andrew Rowland ◽

Madelé van Dyk ◽

Ashley M. Hopkins ◽

Reham Mounzer ◽

Thomas M. Polasek ◽

...

Keyword(s):

Drug Exposure ◽

Pharmacokinetic Modeling ◽

Molecular Characteristics ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically Based Pharmacokinetic Modeling of Renally Cleared Drugs in Pregnant Women

Clinical Pharmacokinetics ◽

10.1007/s40262-017-0538-0 ◽

2017 ◽

Vol 56 (12) ◽

pp. 1525-1541 ◽

Author(s):

André Dallmann ◽

Ibrahim Ince ◽

Juri Solodenko ◽

Michaela Meyer ◽

Stefan Willmann ◽

...

Keyword(s):

Pregnant Women ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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