Physiologically‐Based Pharmacokinetic Modeling Analysis for Quantitative Prediction of Renal Transporter–Mediated Interactions Between Metformin and Cimetidine

Kotaro Nishiyama; Kota Toshimoto; Wooin Lee; Naoki Ishiguro; Bojan Bister; Yuichi Sugiyama

doi:10.1002/psp4.12398

Physiologically‐Based Pharmacokinetic Modeling Analysis for Quantitative Prediction of Renal Transporter–Mediated Interactions Between Metformin and Cimetidine

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12398 ◽

2019 ◽

Vol 8 (6) ◽

pp. 396-406 ◽

Cited By ~ 7

Author(s):

Kotaro Nishiyama ◽

Kota Toshimoto ◽

Wooin Lee ◽

Naoki Ishiguro ◽

Bojan Bister ◽

...

Keyword(s):

Pharmacokinetic Modeling ◽

Quantitative Prediction ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Modeling Analysis ◽

Physiologically Based ◽

Renal Transporter

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Erratum: Physiologically‐Based Pharmacokinetic Modeling Analysis for Quantitative Prediction of Renal Transporter–Mediated Interactions Between Metformin and Cimetidine

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12539 ◽

2020 ◽

Vol 9 (10) ◽

pp. 606-608

Keyword(s):

Pharmacokinetic Modeling ◽

Quantitative Prediction ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Modeling Analysis ◽

Physiologically Based ◽

Renal Transporter

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Prediction of Renal Transporter Mediated Drug-Drug Interactions for Pemetrexed Using Physiologically Based Pharmacokinetic Modeling

Drug Metabolism and Disposition ◽

10.1124/dmd.114.059618 ◽

2014 ◽

Vol 43 (3) ◽

pp. 325-334 ◽

Cited By ~ 36

Author(s):

Maria M. Posada ◽

James A. Bacon ◽

Karen B. Schneck ◽

Rommel G. Tirona ◽

Richard B. Kim ◽

...

Keyword(s):

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Renal Transporter

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Effective Removal of Dabigatran by Idarucizumab or Hemodialysis: A Physiologically Based Pharmacokinetic Modeling Analysis

Clinical Pharmacokinetics ◽

10.1007/s40262-019-00857-y ◽

2020 ◽

Vol 59 (6) ◽

pp. 809-825

Author(s):

Laura Maria Fuhr ◽

Nina Hanke ◽

Bernd Meibohm ◽

Thorsten Lehr

Keyword(s):

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Modeling Analysis ◽

Effective Removal ◽

Physiologically Based

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Physiologically Based Pharmacokinetic Modeling Framework for Quantitative Prediction of an Herb-Drug Interaction

CPT Pharmacometrics & Systems Pharmacology ◽

10.1038/psp.2013.69 ◽

2014 ◽

Vol 3 (3) ◽

pp. 107 ◽

Cited By ~ 25

Author(s):

SJ Brantley ◽

BT Gufford ◽

R Dua ◽

DJ Fediuk ◽

TN Graf ◽

...

Keyword(s):

Drug Interaction ◽

Pharmacokinetic Modeling ◽

Quantitative Prediction ◽

Physiologically Based Pharmacokinetic Modeling ◽

Modeling Framework ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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The Quantitative Prediction of CYP-mediated Drug Interaction by Physiologically Based Pharmacokinetic Modeling

Pharmaceutical Research ◽

10.1007/s11095-008-9607-2 ◽

2008 ◽

Vol 25 (8) ◽

pp. 1891-1901 ◽

Cited By ~ 84

Author(s):

Motohiro Kato ◽

Yoshihisa Shitara ◽

Hitoshi Sato ◽

Kunihiro Yoshisue ◽

Masaru Hirano ◽

...

Keyword(s):

Drug Interaction ◽

Pharmacokinetic Modeling ◽

Quantitative Prediction ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Quantitative Prediction of Drug–Drug Interactions Involving Inhibitory Metabolites in Drug Development: How Can Physiologically Based Pharmacokinetic Modeling Help?

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12110 ◽

2016 ◽

Vol 5 (10) ◽

pp. 505-515 ◽

Cited By ~ 7

Author(s):

IE Templeton ◽

Y Chen ◽

J Mao ◽

J Lin ◽

H Yu ◽

...

Keyword(s):

Drug Development ◽

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Quantitative Prediction ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Quantitative prediction of breast cancer resistant protein (BCRP) mediated drug‐drug interactions using physiologically‐based pharmacokinetic modeling

CPT Pharmacometrics & Systems Pharmacology ◽

10.1002/psp4.12672 ◽

2021 ◽

Author(s):

Chester Costales ◽

Jian Lin ◽

Emi Kimoto ◽

Shinji Yamazaki ◽

James R. Gosset ◽

...

Keyword(s):

Breast Cancer ◽

Drug Interactions ◽

Pharmacokinetic Modeling ◽

Quantitative Prediction ◽

Physiologically Based Pharmacokinetic Modeling ◽

Breast Cancer Resistant Protein ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Utilizing In Vitro Dissolution-Permeation Chamber for the Quantitative Prediction of pH-Dependent Drug-Drug Interactions with Acid-Reducing Agents: a Comparison with Physiologically Based Pharmacokinetic Modeling

The AAPS Journal ◽

10.1208/s12248-016-9972-4 ◽

2016 ◽

Vol 18 (6) ◽

pp. 1512-1523 ◽

Cited By ~ 11

Author(s):

Andy Z. X. Zhu ◽

Ming-Chih David Ho ◽

Christopher K. Gemski ◽

Bei-Ching Chuang ◽

Mingxiang Liao ◽

...

Keyword(s):

Drug Interactions ◽

Reducing Agents ◽

Pharmacokinetic Modeling ◽

In Vitro Dissolution ◽

Quantitative Prediction ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Ph Dependent

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Physiologically-based pharmacokinetic modeling of different size polyethylene glycol-coated gold nanoparticles in mice

10.1615/ihtc16.nmt.023362 ◽

2018 ◽

Author(s):

Linjing Deng ◽

Jinping Zhao ◽

Yufeng Miao ◽

Xu Hu ◽

Qihong Deng

Keyword(s):

Gold Nanoparticles ◽

Polyethylene Glycol ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Physiologically-Based Pharmacokinetic Modeling to Predict Changes in Drug Exposure during Pregnancy Using the Simcyp Simulator

10.26226/morressier.57d6b2b7d462b8028d88e945 ◽

2016 ◽

Author(s):

Suvarchala Kiranmai Avvari

Keyword(s):

Drug Exposure ◽

Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic Modeling ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Exposure During Pregnancy

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