Utilizing In Vitro Dissolution-Permeation Chamber for the Quantitative Prediction of pH-Dependent Drug-Drug Interactions with Acid-Reducing Agents: a Comparison with Physiologically Based Pharmacokinetic Modeling

In Vitro Dissolution ◽

Quantitative Prediction ◽

Physiologically Based ◽

Ph Dependent

Quantitative Prediction of Drug–Drug Interactions Involving Inhibitory Metabolites in Drug Development: How Can Physiologically Based Pharmacokinetic Modeling Help?

10.1002/psp4.12110 ◽

2016 ◽

Vol 5 (10) ◽

pp. 505-515 ◽

Cited By ~ 7

Author(s):

IE Templeton ◽

Y Chen ◽

J Mao ◽

J Lin ◽

H Yu ◽

...

Keyword(s):

Drug Development ◽

Drug Interactions ◽

Quantitative Prediction ◽

Investigating the Impact of Drug Crystallinity in Amorphous Tacrolimus Capsules on Pharmacokinetics and Bioequivalence Using Discriminatory In Vitro Dissolution Testing and Physiologically Based Pharmacokinetic Modeling and Simulation

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2017.12.024 ◽

2018 ◽

Vol 107 (5) ◽

pp. 1330-1341 ◽

Cited By ~ 22

Author(s):

Hitesh S. Purohit ◽

Niraj S. Trasi ◽

Dajun D. Sun ◽

Edwin C.Y. Chow ◽

Hong Wen ◽

...

Keyword(s):

Modeling And Simulation ◽

In Vitro Dissolution ◽

Dissolution Testing ◽

Pharmacokinetic Modeling And Simulation

Physiologically Based ◽

The Impact ◽

Quantitative prediction of breast cancer resistant protein (BCRP) mediated drug‐drug interactions using physiologically‐based pharmacokinetic modeling

10.1002/psp4.12672 ◽

2021 ◽

Author(s):

Chester Costales ◽

Jian Lin ◽

Emi Kimoto ◽

Shinji Yamazaki ◽

James R. Gosset ◽

...

Keyword(s):

Breast Cancer ◽

Drug Interactions ◽

Quantitative Prediction ◽

Breast Cancer Resistant Protein ◽

Application of Physiologically‐Based Pharmacokinetic Modeling to Predict Gastric pH‐Dependent Drug–Drug Interactions for Weak Base Drugs

10.1002/psp4.12541 ◽

2020 ◽

Vol 9 (8) ◽

pp. 456-465

Author(s):

Zhongqi Dong ◽

Jia Li ◽

Fang Wu ◽

Ping Zhao ◽

Sue‐Chih Lee ◽

...

Keyword(s):

Drug Interactions ◽

Gastric Ph ◽

Weak Base ◽

Physiologically Based ◽

Ph Dependent

Physiologically Based Pharmacokinetic Modeling Approach to Predict Drug‐Drug Interactions With Ethionamide Involving Impact of Genetic Polymorphism on FMO3

The Journal of Clinical Pharmacology ◽

10.1002/jcph.1378 ◽

2019 ◽

Vol 59 (6) ◽

pp. 880-889 ◽

Cited By ~ 1

Author(s):

Phuong Thi Thu Nguyen ◽

Md Masud Parvez ◽

Min Jung Kim ◽

Sung Eun Yoo ◽

Sangzin Ahn ◽

...

Keyword(s):

Genetic Polymorphism ◽

Drug Interactions ◽

Modeling Approach ◽

Advancing Predictions of Tissue and Intracellular Drug Concentrations Using In Vitro , Imaging and Physiologically Based Pharmacokinetic Modeling Approaches

Clinical Pharmacology & Therapeutics ◽

10.1002/cpt.1183 ◽

2018 ◽

Vol 104 (5) ◽

pp. 865-889 ◽

Cited By ~ 42

Author(s):

Yingying Guo ◽

Xiaoyan Chu ◽

Neil J. Parrott ◽

Kim L.R. Brouwer ◽

Vicky Hsu ◽

...

Keyword(s):

Modeling Approaches ◽

Drug Concentrations ◽

Physiologically based pharmacokinetic modeling to predict complex drug-drug interactions: a case study of AZD2327 and its metabolite, competitive and time-dependent CYP3A inhibitors

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.1962 ◽

2015 ◽

Vol 36 (8) ◽

pp. 507-519 ◽

Cited By ~ 4

Author(s):

Jian Guo ◽

Diansong Zhou ◽

Yan Li ◽

Bui H. Khanh

Keyword(s):

Drug Interactions ◽

Time Dependent ◽

Physiologically Based ◽

Complex Drug

Pain Chemogenomics Knowledgebase (Pain-CKB) for Systems Pharmacology Target Mapping and Physiologically Based Pharmacokinetic Modeling Investigation of Opioid Drug–Drug Interactions

ACS Chemical Neuroscience ◽

10.1021/acschemneuro.0c00372 ◽

2020 ◽

Vol 11 (20) ◽

pp. 3245-3258

Author(s):

Mingzhe Shen ◽

Maozi Chen ◽

Tianjian Liang ◽

Siyi Wang ◽

Ying Xue ◽

...

Keyword(s):

Drug Interactions ◽

Systems Pharmacology ◽

Implementation of a Physiologically Based Pharmacokinetic Modeling Approach to Guide Optimal Dosing Regimens for Imatinib and Potential Drug Interactions in Paediatrics

Frontiers in Pharmacology ◽

10.3389/fphar.2019.01672 ◽

2020 ◽

Vol 10 ◽

Cited By ~ 2

Author(s):

Jeffry Adiwidjaja ◽

Alan V. Boddy ◽

Andrew J. McLachlan

Keyword(s):

Drug Interactions ◽

Potential Drug ◽

Modeling Approach ◽

Optimal Dosing ◽

Physiologically Based ◽

Dosing Regimens

Physiologically‐Based Pharmacokinetic Modeling for Predicting Drug Interactions of a Combination of Olanzapine and Samidorphan

10.1002/psp4.12488 ◽

2020 ◽

Vol 9 (2) ◽

pp. 106-114 ◽

Cited By ~ 2

Author(s):

Lei Sun ◽

Lisa Moltke ◽

Karen Rowland Yeo

Keyword(s):

Drug Interactions ◽