scholarly journals Quantitative Systems Pharmacology Models for a New International Cardiac Safety Regulatory Paradigm: An Overview of the Comprehensive In Vitro Proarrhythmia Assay In Silico Modeling Approach

2019 ◽  
Vol 8 (6) ◽  
pp. 371-379 ◽  
Author(s):  
Zhihua Li ◽  
Christine Garnett ◽  
David G. Strauss
Keyword(s):  
In Silico ◽  
Systems Pharmacology ◽  
Cardiac Safety ◽  
Quantitative Systems Pharmacology ◽  
Modeling Approach ◽  
In Silico Modeling

In Vitro–In Silico Modeling Approach to Rationally Designed Simple and Versatile Drug Delivery Systems

2020 ◽  
Vol 124 (28) ◽  
pp. 5788-5800 ◽  
Author(s):  
Belén L. Bouzo ◽  
Martín Calvelo ◽  
Manuel Martín-Pastor ◽  
Rebeca García-Fandiño ◽  
María de la Fuente
Keyword(s):  
Drug Delivery ◽  
In Silico ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Modeling Approach ◽  
In Silico Modeling

In vitro and in silico modeling of endovascular stroke treatments for acute ischemic stroke

2021 ◽  
pp. 110693
Author(s):  
Giulia Luraghi ◽  
Rachel M. E. Cahalane ◽  
Emma van de Ven ◽  
Serena Overschie ◽  
Frank J. H. Gijsen ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Acute Ischemic Stroke ◽  
In Silico ◽  
In Silico Modeling

In Silico Modeling Approach for the Evaluation of Gastrointestinal Dissolution, Supersaturation, and Precipitation of Posaconazole

2017 ◽  
Vol 14 (12) ◽  
pp. 4321-4333 ◽  
Author(s):  
Bart Hens ◽  
Shriram M. Pathak ◽  
Amitava Mitra ◽  
Nikunjkumar Patel ◽  
Bo Liu ◽  
...  
Keyword(s):  
In Silico ◽  
Modeling Approach ◽  
In Silico Modeling

scholarly journals An in vitro quantitative systems pharmacology approach for deconvolving mechanisms of drug-induced, multilineage cytopenias

2020 ◽  
Vol 16 (7) ◽  
pp. e1007620
Author(s):  
Jennifer L. Wilson ◽  
Dan Lu ◽  
Nick Corr ◽  
Aaron Fullerton ◽  
James Lu
Keyword(s):  
Systems Pharmacology ◽  
Drug Induced ◽  
Quantitative Systems Pharmacology

scholarly journals In vitro and in silico modeling of perfluoroalkyl substances mixture toxicity in an amphibian fibroblast cell line

Chemosphere ◽  
2019 ◽  
Vol 233 ◽  
pp. 25-33 ◽  
Author(s):  
Gary Hoover ◽  
Supratik Kar ◽  
Samuel Guffey ◽  
Jerzy Leszczynski ◽  
Maria S. Sepúlveda
Keyword(s):  
Cell Line ◽  
In Silico ◽  
Mixture Toxicity ◽  
Fibroblast Cell ◽  
Perfluoroalkyl Substances ◽  
Fibroblast Cell Line ◽  
In Silico Modeling
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