The effects of lemon balm ( Melissa officinalis L.) on depression and anxiety in clinical trials: A systematic review and meta‐analysis

2021 ◽  
Author(s):  
Javid Ghazizadeh ◽  
Saeed Sadigh‐Eteghad ◽  
Wolfgang Marx ◽  
Ali Fakhari ◽  
Sanaz Hamedeyazdan ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Meta Analysis ◽  
Depression And Anxiety ◽  
Melissa Officinalis ◽  
Lemon Balm

Effects of Melissa officinalis (Lemon Balm) on cardio‐metabolic outcomes: A systematic review and meta‐analysis

2020 ◽  
Vol 34 (12) ◽  
pp. 3113-3123 ◽  
Author(s):  
Javad Heshmati ◽  
Mojgan Morvaridzadeh ◽  
Mahdi Sepidarkish ◽  
Siavash Fazelian ◽  
Mehran Rahimlou ◽  
...  
Keyword(s):  
Systematic Review ◽  
Meta Analysis ◽  
Melissa Officinalis ◽  
Lemon Balm ◽  
Metabolic Outcomes

scholarly journals Psilocybin as a New Approach to Treat Depression and Anxiety in the Context of Life-Threatening Diseases—A Systematic Review and Meta-Analysis of Clinical Trials

Biomedicines ◽  
2020 ◽  
Vol 8 (9) ◽  
pp. 331 ◽  
Author(s):  
Ana Sofia Vargas ◽  
Ângelo Luís ◽  
Mário Barroso ◽  
Eugenia Gallardo ◽  
Luísa Pereira
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Meta Analysis ◽  
Intervention Group ◽  
Effect Sizes ◽  
P Value ◽  
Therapeutic Effects ◽  
Depression And Anxiety ◽  
Symptoms Of Depression ◽  
Life Threatening

Psilocybin is a naturally occurring tryptamine known for its psychedelic properties. Recent research indicates that psilocybin may constitute a valid approach to treat depression and anxiety associated to life-threatening diseases. The aim of this work was to perform a systematic review with meta-analysis of clinical trials to assess the therapeutic effects and safety of psilocybin on those medical conditions. The Beck Depression Inventory (BDI) was used to measure the effects in depression and the State-Trait Anxiety Inventory (STAI) was used to measure the effects in anxiety. For BDI, 11 effect sizes were considered (92 patients) and the intervention group was significantly favored (WMD = −4.589; 95% CI = −4.207 to −0.971; p-value = 0.002). For STAI-Trait, 11 effect sizes were considered (92 patients), being the intervention group significantly favored when compared to the control group (WMD = −5.906; 95% CI = −7.852 to −3.960; p-value ˂ 0.001). For STAI-State, 9 effect sizes were considered (41 patients) and the intervention group was significantly favored (WMD = −6.032; 95% CI = −8.900 to −3.164; p-value ˂ 0.001). The obtained results are promising and emphasize the importance of psilocybin translational research in the management of symptoms of depression and anxiety, since the compound may be effective in reducing symptoms of depression and anxiety in conditions that are either resistant to conventional pharmacotherapy or for which pharmacologic treatment is not yet approved. Moreover, it may be also relevant for first-line treatment, given its safety.

ANTERIOR VERSUS POSTERIOR MYOTOMY DURING POEM FOR THE TREATMENT OF ACHALASIA: SYSTEMATIC REVIEW AND META-ANALYSIS OF RANDOMIZED CLINICAL TRIALS

2019 ◽  
Author(s):  
E Rodríguez de Santiago ◽  
N Mohammed ◽  
A Manolakis ◽  
Y Shimamura ◽  
M Onimaru ◽  
...  
Keyword(s):  
Systematic Review ◽  
Clinical Trials ◽  
Randomized Clinical Trials ◽  
Meta Analysis
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