The effect of capsaicin on blood glucose, plasma insulin levels and insulin binding in dog models

2001 ◽  
Vol 15 (5) ◽  
pp. 391-394 ◽  
Author(s):  
I. Tolan ◽  
D. Ragoobirsingh ◽  
E. Y. St. A. Morrison
1991 ◽  
Vol 66 (3) ◽  
pp. 363-379 ◽  
Author(s):  
Peter R. Ellis ◽  
Fathy M. Dawoud ◽  
Edwin R. Morris

The effectiveness of guar gum in reducing post-prandial blood glucose and plasma insulin levels in human subjects seems to depend mainly on its ability to increase the viscosity of digesta in the small intestine. However, the precise relationship between the rheological properties of guar gum (either in vitro or in vivo) and the changes in blood metabolites and hormones is unknown. The aim of the present study, therefore, was to investigate the effects of wheat breads containing guar gum samples varying in molecular weight (Mw) and particle size (characteristics that strongly influence the rheological properties of guar gum) on post-prandial blood glucose and plasma insulin levels in healthy subjects. The sensory qualities of breads containing guar-gum flours of different Mw were also evaluated using a hedonic scoring technique. No significant differences in the post-prandial blood glucose responses were found between the control and guar breads. However, all the guar breads elicited significant (P < 0.05) decreases in the post-prandial rise in plasma insulin, an effect that did not appear to be influenced by large variations in Mw or particle size of guar gum. Moreover, the sensory qualities of guar bread were markedly improved by using low Mw grades of guar gum.


Diabetologia ◽  
1974 ◽  
Vol 10 (6) ◽  
pp. 725-730 ◽  
Author(s):  
M. Hautecouverture ◽  
G. Slama ◽  
R. Assan ◽  
G. Tchobroutsky

PEDIATRICS ◽  
1969 ◽  
Vol 44 (3) ◽  
pp. 381-392
Author(s):  
Katherine C. King ◽  
Peter A. J. Adam ◽  
Geronima A. Clemente ◽  
Robert Schwartz

Blood glucose, plasma insulin, and free fatty acid interrelationships were examined in newborn infants during and after continuous hourly glucose infusions at rates varying from 4 to 24 mg/kg/minute. Normal newborn infants disposed of glucose efficiently until glucose was infused at rates greater than 6 mg/kg/minute. Plasma insulin levels rose gradually during glucose infusion. When large loads of glucose infusion were initiated (12 mg/kg/minute), however, there was a delay in plasma insulin rise. At the slow rates of glucose infusion, the infants of gestational or insulin-dependent diabetic mothers disposed of the exogenous glucose more slowly than the normal newborns. Plasma insulin levels in the infants of gestational diabetic mothers were similar to those in the normal infants. These observations suggest that, with comparable glucose stimulus by continuous infusion, the infants of diabetic mothers do not have excessive insulin output.


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