The evaluation and implementation of direct analysis in real time quadrupole time-of-flight tandem mass spectrometry for characterization and quantification of geniposide in Re Du Ning Injections

2012 ◽  
Vol 26 (11) ◽  
pp. 1377-1384 ◽  
Author(s):  
Yan-Jing Li ◽  
Zhen-Zhong Wang ◽  
Yu-An Bi ◽  
Gang Ding ◽  
Long-Sheng Sheng ◽  
...  







2017 ◽  
Vol 35 (2) ◽  
pp. 185 ◽  
Author(s):  
Xiaoming GONG ◽  
Ronghui MA ◽  
Hongtao WANG ◽  
Liqiang GUO ◽  
Kai LI ◽  
...  


2015 ◽  
Vol 100 ◽  
pp. 74-77 ◽  
Author(s):  
Ákos Kuki ◽  
Lajos Nagy ◽  
Tibor Nagy ◽  
Miklós Zsuga ◽  
Sándor Kéki


2019 ◽  
Vol 9 (1) ◽  
Author(s):  
Xinglei Zhang ◽  
Miaorong Pei ◽  
Debo Wu ◽  
Shuiping Yang ◽  
Zhanggao Le

AbstractIn this work an on-line monitoring method was developed to study the mechanism of acetic acid catalyzed reaction between aniline and acetonylacetone using extractive electorspray ionization-tandem mass spectrometry (EESI-MS). The signals of reactants, intermediates and various byproducts were continuously detected as a function of reaction time. The chemical assignment of each signal was done via multi-stage collision induced dissociation (CID) analysis, and the reaction mechanism between aniline and acetonylacetone was deduced based on the generated molecular ions and fragment ions. The results indicate that on-line EESI-MS is an effective technique for the real time analysis of chemical reactions. EESI avoids off-line sample pretreatment and provides “soft” ionization, which allows direct analysis of various analytes at molecular level.



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