Test–retest variability and reliability of123I-IBZM SPECT measurement of striatal dopamine D2 receptor availability in healthy volunteers and influence of iterative reconstruction algorithms

Synapse ◽  
2007 ◽  
Vol 62 (1) ◽  
pp. 62-69 ◽  
Author(s):  
Ana M. Catafau ◽  
Santiago Bullich ◽  
Mónica Danús ◽  
María M. Penengo ◽  
Albert Cot ◽  
...  
2014 ◽  
Vol 2014 ◽  
pp. 1-10 ◽  
Author(s):  
Qing Ye ◽  
Xiao-Lei Yuan ◽  
Jie Zhou ◽  
Can-xing Yuan ◽  
Xu-ming Yang

This study was performed to observe the effects of Zishenpingchan granule on neurobehavioral manifestations and the activity and gene expression of striatal dopamine D1 and D2 receptors of rats with levodopa-induced dyskinesias (LID). We established normal control group, LID model group, and TCM intervention group. Each group received treatment for 4 weeks. Artificial neural network (ANN) was applied to excavate the main factor influencing variation in neurobehavioral manifestations of rats with LID. The results showed that overactivation in direct pathway mediated by dopamine D1 receptor and overinhibition in indirect pathway mediated by dopamine D2 receptor may be the main mechanism of LID. TCM increased the efficacy time of LD to ameliorate LID symptoms effectively mainly by upregulating dopamine D2 receptor gene expression.


1998 ◽  
Vol 29 (1-2) ◽  
pp. 166 ◽  
Author(s):  
T.J. Raedler ◽  
M.B. Knable ◽  
T. Lafargue ◽  
D. Pickar ◽  
D.R. Weinberger

2011 ◽  
Vol 18 (6) ◽  
pp. 908-911 ◽  
Author(s):  
Cleo L. Crunelle ◽  
Elsmarieke van de Giessen ◽  
Sybille Schulz ◽  
Louk J. M. J. Vanderschuren ◽  
Kora de Bruin ◽  
...  

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