Human nail bed‐derived decellularized scaffold regulates mesenchymal stem cells for nail plate regeneration

2019 ◽  
Vol 13 (10) ◽  
pp. 1770-1778 ◽  
Author(s):  
Yaling Yu ◽  
Haomin Cui ◽  
Demin Zhang ◽  
Bo Liang ◽  
Yimin Chai ◽  
...  
2010 ◽  
Vol 2010 ◽  
pp. 1-6 ◽  
Author(s):  
Tracy Frech ◽  
Nathan Hatton ◽  
Boaz Markewitz ◽  
Mary Beth Scholand ◽  
Richard Cawthon ◽  
...  

The role of the vascular microenvironment in the pathogenesis Systemic Sclerosis (SSc) is appreciated clinically as Raynaud's syndrome with capillary nail bed change. This manifestation of vasculopathy is used diagnostically in both limited and diffuse cutaneous subsets of SSc, and is thought to precede fibrosis. The degree of subsequent fibrosis may also be determined by the vascular microenvironment. This paper describes why the vascular microenvironment might determine the degree of end-organ damage that occurs in SSc, with a focus on vascular cell senescence, endothelial progenitor cells (EPC) including multipotential mesenchymal stem cells (MSC), pericytes, and angiogenic monocytes. An explanation of the role of EPC, pericytes, and angiogenic monocytes is important to an understanding of SSc pathogenesis. An evolving understanding of the vascular microenvironment in SSc may allow directed treatment.


Biomaterials ◽  
2010 ◽  
Vol 31 (2) ◽  
pp. 296-307 ◽  
Author(s):  
Yilin Zhao ◽  
Su Zhang ◽  
Jianyin Zhou ◽  
Jinling Wang ◽  
Maochuan Zhen ◽  
...  

2010 ◽  
Vol 30 (6) ◽  
pp. 455-455 ◽  
Author(s):  
Dongyan Shi ◽  
Dan Ma ◽  
Feiqing Dong ◽  
Chen Zong ◽  
Liyue Liu ◽  
...  

2004 ◽  
Vol 171 (4S) ◽  
pp. 373-373
Author(s):  
Trinity J. Bivalacqua ◽  
Mustafa F. Usta ◽  
Hunter C. Champion ◽  
Weiwen Deng ◽  
Philip J. Kadowitz ◽  
...  

2008 ◽  
Vol 68 (S 01) ◽  
Author(s):  
S Mohr ◽  
BC Portmann-Lanz ◽  
A Schoeberlein ◽  
R Sager ◽  
DV Surbek

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