scholarly journals The MLO1 powdery mildew susceptibility gene in Lathyrus species: The power of high‐density linkage maps in comparative mapping and synteny analysis

2021 ◽  
Author(s):  
Carmen Santos ◽  
Carlos Polanco ◽  
Diego Rubiales ◽  
Maria Carlota Vaz Patto
Keyword(s):  
Powdery Mildew ◽  
Comparative Mapping ◽  
Susceptibility Gene ◽  
High Density ◽  
Linkage Maps ◽  
Synteny Analysis

scholarly journals Construction of High-Density Linkage Maps of Populus deltoides × P. simonii Using Restriction-Site Associated DNA Sequencing

PLoS ONE ◽  
2016 ◽  
Vol 11 (3) ◽  
pp. e0150692 ◽  
Author(s):  
Chunfa Tong ◽  
Huogen Li ◽  
Ying Wang ◽  
Xuran Li ◽  
Jiajia Ou ◽  
...  
Keyword(s):  
Dna Sequencing ◽  
Restriction Site ◽  
Populus Deltoides ◽  
High Density ◽  
Linkage Maps

scholarly journals Advanced Strategies in Bulked Segregant Analysis and its Applications

2021 ◽  
Author(s):  
Harshavardan J. Hilli
Keyword(s):  
Genetic Markers ◽  
Mapping Population ◽  
Bulked Segregant Analysis ◽  
High Density ◽  
Mutant Phenotype ◽  
Linkage Maps ◽  
Quick Method ◽  
Reduced Time

Bulked segregant analysis (BSA) is a technique used to identify genetic markers associated with a mutant phenotype and is a quick method for identifying markers in particular genome regions. The paper focussed on Advanced methods which escape the requirement of genotyping all the individuals of the mapping population and generation of high-density linkage maps for mapping of the gene for the trait of interest. With the emergence of re-sequencing techniques, quick mapping of genes has become possible with reduced time and cost by using advanced methodologies like MutMap, MutMap+, MutMap-Gap, QTL-Seq, RNAseq BSA, NGS BSA and QTG seq. The procedure for various advanced BSA strategies has been described.

Construction of high-density linkage maps and QTL mapping for growth-related traits in F1 hybrid Yunlong grouper (Epinephelus moara♀ × E. lanceolatus♂)

Aquaculture ◽  
2021 ◽  
pp. 737698
Author(s):  
Yang Liu ◽  
Yongsheng Tian ◽  
Linna Wang ◽  
Zhentong Li ◽  
Jingjing Zhang ◽  
...  
Keyword(s):  
Qtl Mapping ◽  
High Density ◽  
Linkage Maps ◽  
F1 Hybrid

High-density linkage maps and loci for berry color and flower sex in muscadine grape (Vitis rotundifolia)

2019 ◽  
Vol 132 (5) ◽  
pp. 1571-1585 ◽  
Author(s):  
Jennifer Lewter ◽  
Margaret L. Worthington ◽  
John R. Clark ◽  
Aruna V. Varanasi ◽  
Lacy Nelson ◽  
...  
Keyword(s):  
High Density ◽  
Linkage Maps ◽  
Vitis Rotundifolia ◽  
Muscadine Grape

scholarly journals Construction of high-density genetic linkage maps for orange-spotted grouper Epinephelus coioides using multiplexed shotgun genotyping

BMC Genetics ◽  
2013 ◽  
Vol 14 (1) ◽  
pp. 113 ◽  
Author(s):  
Xinxin You ◽  
Liping Shu ◽  
Shuisheng Li ◽  
Jieming Chen ◽  
Jian Luo ◽  
...  
Keyword(s):  
Genetic Linkage ◽  
High Density ◽  
Epinephelus Coioides ◽  
Linkage Maps ◽  
Genetic Linkage Maps

scholarly journals A high-density SNP genome-wide linkage search of 206 families identifies susceptibility loci for chronic lymphocytic leukemia

Blood ◽  
2007 ◽  
Vol 110 (9) ◽  
pp. 3326-3333 ◽  
Author(s):  
Gabrielle S. Sellick ◽  
Lynn R. Goldin ◽  
Ruth W. Wild ◽  
Susan L. Slager ◽  
Laura Ressenti ◽  
...  
Keyword(s):  
Chronic Lymphocytic Leukemia ◽  
Familial Aggregation ◽  
Susceptibility Gene ◽  
Snp Array ◽  
High Density ◽  
Lymphocytic Leukemia ◽  
Nonparametric Model ◽  
Model Free ◽  
Genome Wide ◽  
A Genome

Abstract Chronic lymphocytic leukemia (CLL) and other B-cell lymphoproliferative disorders display familial aggregation. To identify a susceptibility gene for CLL, we assembled families from the major European (ICLLC) and American (GEC) consortia to conduct a genome-wide linkage analysis of 101 new CLL pedigrees using a high-density single nucleotide polymorphism (SNP) array and combined the results with data from our previously reported analysis of 105 families. Here, we report on the combined analysis of the 206 families. Multipoint linkage analyses were undertaken using both nonparametric (model-free) and parametric (model-based) methods. After the removal of high linkage disequilibrium SNPs, we obtained a maximum nonparametric linkage (NPL) score of 3.02 (P = .001) on chromosome 2q21.2. The same genomic position also yielded the highest multipoint heterogeneity LOD (HLOD) score under a common recessive model of disease susceptibility (HLOD = 3.11; P = 7.7 × 10−5), which was significant at the genome-wide level. In addition, 2 other chromosomal positions, 6p22.1 (corresponding to the major histocompatibility locus) and 18q21.1, displayed HLOD scores higher than 2.1 (P < .002). None of the regions coincided with areas of common chromosomal abnormalities frequently observed in CLL. These findings provide direct evidence for Mendelian predisposition to CLL and evidence for the location of disease loci.

Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels

Genomics ◽  
2005 ◽  
Vol 86 (5) ◽  
pp. 505-517 ◽  
Author(s):  
Alessandra C. Cervino ◽  
Guoya Li ◽  
Steve Edwards ◽  
Jun Zhu ◽  
Cathy Laurie ◽  
...  
Keyword(s):  
Plasma Cholesterol ◽  
Susceptibility Gene ◽  
High Density ◽  
Cholesterol Levels

scholarly journals Recent Advances in Molecular Genetic Linkage Maps of Cultivated Peanut

2013 ◽  
Vol 40 (2) ◽  
pp. 95-106 ◽  
Author(s):  
Baozhu Guo ◽  
Manish K. Pandey ◽  
Guohao He ◽  
Xinyou Zhang ◽  
Boshou Liao ◽  
...  
Keyword(s):  
Genetic Linkage ◽  
High Density ◽  
Genetic Maps ◽  
Linkage Maps ◽  
Consensus Map ◽  
Genetic Linkage Maps ◽  
Marker Loci ◽  
Cultivated Peanut ◽  
Peanut Genome ◽  
Mapping Populations

ABSTRACT The competitiveness of peanuts in domestic and global markets has been threatened by losses in productivity and quality that are attributed to diseases, pests, environmental stresses and allergy or food safety issues. Narrow genetic diversity and a deficiency of polymorphic DNA markers severely hindered construction of dense genetic maps and quantitative trait loci (QTL) mapping in order to deploy linked markers in marker-assisted peanut improvement. The U.S. Peanut Genome Initiative (PGI) was launched in 2004, and expanded to a global effort in 2006 to address these issues through coordination of international efforts in genome research beginning with molecular marker development and improvement of map resolution and coverage. Ultimately, a peanut genome sequencing project was launched in 2012 by the Peanut Genome Consortium (PGC). We reviewed the progress for accelerated development of peanut genomic resources in peanut, such as generation of expressed sequenced tags (ESTs) (252,832 ESTs as December 2012 in the public NCBI EST database), development of molecular markers (over 15,518 SSRs), and construction of peanut genetic linkage maps, in particular for cultivated peanut. Several consensus genetic maps have been constructed, and there are examples of recent international efforts to develop high density maps. An international reference consensus genetic map was developed recently with 897 marker loci based on 11 published mapping populations. Furthermore, a high-density integrated consensus map of cultivated peanut and wild diploid relatives also has been developed, which was enriched further with 3693 marker loci on a single map by adding information from five new genetic mapping populations to the published reference consensus map.

scholarly journals High-density linkage maps fail to detect any genetic component to sex determination in a Rana temporaria family

2015 ◽  
Vol 29 (1) ◽  
pp. 220-225 ◽  
Author(s):  
A. Brelsford ◽  
N. Rodrigues ◽  
N. Perrin
Keyword(s):  
Sex Determination ◽  
Rana Temporaria ◽  
High Density ◽  
Genetic Component ◽  
Linkage Maps
Sign in / Sign up

Export Citation Format

Share Document