<b><i>Objective:</i></b> The objective of this study is to assess the effectiveness and safety of intrafetal vascular laser ablation (VLA) for fetuses with bronchopulmonary sequestration (BPS) with hydrops. <b><i>Methods:</i></b> First, we present 3 cases of fetuses with BPS and hydrops treated by VLA. Second, we aimed to conduct a narrative review to identify all reported cases of fetuses with BPS treated by intrafetal VLA. <b><i>Results:</i></b> The review of the literature identified 41 fetuses treated by VLA for BPS with hydrops. The median gestational age of the VLA was 27<sup>+0</sup> weeks’ gestation [25<sup>+0</sup>–31<sup>+0</sup>] with an associated procedure at the same time in 43% of the cases (pleuroamniotic shunt, thoracentesis, and amniodrainage). A second procedure was required in 25% of cases for residual flow in the feeding vessel. No stillbirth or neonatal death was reported. The complications reported were a fetal thoracic hematoma complicated by fetal anemia and 4 preterm deliveries with a rate of 9%. <b><i>Conclusion:</i></b> VLA of the feeding vessel can be an effective treatment but is not without complications. In cases demonstrating cardiac output failure, intrafetal VLA should be considered as a treatment for BPS.
OP13.02: Outcome and longitudinal changes in pulmonary growth, lung mass volume and intrafetal fluid effusions after percutaneous laser ablation of the feeding artery in fetuses with bronchopulmonary sequestration
