Antenatal Management of Bronchopulmonary Sequestration by Intrafetal Vascular Laser Ablation under Ultrasound Control: Narrative Review of the Literature and Report of Three Cases

<b><i>Objective:</i></b> The objective of this study is to assess the effectiveness and safety of intrafetal vascular laser ablation (VLA) for fetuses with bronchopulmonary sequestration (BPS) with hydrops. <b><i>Methods:</i></b> First, we present 3 cases of fetuses with BPS and hydrops treated by VLA. Second, we aimed to conduct a narrative review to identify all reported cases of fetuses with BPS treated by intrafetal VLA. <b><i>Results:</i></b> The review of the literature identified 41 fetuses treated by VLA for BPS with hydrops. The median gestational age of the VLA was 27⁺⁰ weeks’ gestation [25⁺⁰–31⁺⁰] with an associated procedure at the same time in 43% of the cases (pleuroamniotic shunt, thoracentesis, and amniodrainage). A second procedure was required in 25% of cases for residual flow in the feeding vessel. No stillbirth or neonatal death was reported. The complications reported were a fetal thoracic hematoma complicated by fetal anemia and 4 preterm deliveries with a rate of 9%. <b><i>Conclusion:</i></b> VLA of the feeding vessel can be an effective treatment but is not without complications. In cases demonstrating cardiac output failure, intrafetal VLA should be considered as a treatment for BPS.

Efficiency of a low-intensity laser in the treatment of genital herpes infections

90 women at the age of 30,9±0,4 years with clinical laboratory signs of herpetic defeat of urogenital system took part in research lasting 12 months. Therapy included a preparation Valaciclovir on 500 mg, complex therapy was carried out with use of intra vascular laser radiation of blood (wavelength of 365 nm, power of the radiation of 2 mW, an influence exposition the laser of 8 min, the number of sessions 15) along with application of a preparation Valaciclovir. Results of the study indicate a positive clinical dynamics and immunomodulatory action of intravascular laser irradiation of blood that can be recommended as a method of complex treatment of herpetic lesions of the reproductive system.