scholarly journals Head growth in fetuses with isolated congenital heart defects: lack of influence of aortic arch flow and ascending aorta oxygen saturation

2016 ◽  
Vol 48 (3) ◽  
pp. 357-364 ◽  
Author(s):  
F. A. R. Jansen ◽  
E. W. van Zwet ◽  
M. E. B. Rijlaarsdam ◽  
E. Pajkrt ◽  
C. L. van Velzen ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Aortic Arch ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Ascending Aorta ◽  
Head Growth

An unusual case of tetralogy of Fallot with an absent pulmonary valve associated with a retro-aortic innominate vein in a patient with a 16p12.2 microdeletion

2021 ◽  
pp. 1-2
Author(s):  
Niall Linnane ◽  
Andrew Green ◽  
Colin J. McMahon
Keyword(s):  
Aortic Arch ◽  
Tetralogy Of Fallot ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Unusual Case ◽  
Pulmonary Valve ◽  
Heart Defects ◽  
Innominate Vein ◽  
Absent Pulmonary Valve ◽  
Rare Association

Abstract 16p12.2 microdeletion has been associated with congenital heart defects and developmental delay. In this case, we describe the rare association between tetralogy of Fallot with an absent pulmonary valve a right-sided aortic arch and a retro-aortic innominate vein associated with a 16p12.2 microdeletion and epilepsy.

scholarly journals Pulse Oximetry During the First 24 Hours as a Screening Tool For Congenital Heart Defects

2017 ◽  
Vol 3 (1) ◽  
pp. 12-17
Author(s):  
Mihaela Patriciu ◽  
Andreea Avasiloaiei ◽  
Mihaela Moscalu ◽  
Maria Stamatin
Keyword(s):  
Oxygen Saturation ◽  
Pulse Oximetry ◽  
Sensitivity And Specificity ◽  
Congenital Heart Defects ◽  
Screening Test ◽  
Congenital Heart ◽  
Heart Defects ◽  
Blood Oxygen ◽  
Blood Oxygen Saturation ◽  
Routine Pulse Oximetry

Abstract Introduction: Although screening for congenital heart defects (CHD) relies mainly on antenatal ultrasonography and clinical examination after birth, life-threatening cardiac malformations are often not diagnosed before the patient is discharged. Aim: To assess the use of routine pulse oximetry in the delivery room and at 24 hours postpartum, and to study its feasibility as a screening test for CHD. Material and Methods: In this prospective study, all infants born in “Cuza Voda” Maternity Hospital, Iasi, Romania, were enrolled over a thirteen-month period. Preductal oximetry was assessed during the first hour, and postductal oximetry was evaluated at twenty-four hours postpartum. Data were then analyzed to establish the sensitivity and specificity of pulse oximetry, as a screening test for CHD. Results: 5406 infants were included in the study, with a mean gestational age of 38.2 weeks and a mean birth weight of 3175 grams. During the first minute, blood oxygen saturation varied between 40% and 90% and at 24 hours of life, it ranged between 90% and 100%. Following oximetry assessment, 14 infants with critical CHD were identified. Blood oxygen saturation values in infants with CHD were lower throughout the entire period of evaluation. Pulse oximetry had good sensitivity and specificity at 1 hour (Se=87.5%, Sp=95.5%) and 24 hours (Se=92.5%, Sp=97.4%) for the diagnosis of CHD. Blood oxygen saturation values at one minute, 1 hour and 24 hours are strong discriminative parameters for the early diagnosis of CHD. Conclusion: Routine pulse oximetry during the first 24 hours postpartum represents an early indicator of CHD to facilitate timely intervention. Pulse oximetry provides excellent sensitivity and specificity and has tremendous potential as a standard screening test for CHD during the first 24 hours of life.

scholarly journals Embryonic aortic arch hemodynamics are a functional biomarker for ethanol-induced congenital heart defects [Invited]

2017 ◽  
Vol 8 (3) ◽  
pp. 1823 ◽  
Author(s):  
Lindsy M. Peterson ◽  
Shi Gu ◽  
Ganga Karunamuni ◽  
Michael W. Jenkins ◽  
Michiko Watanabe ◽  
...  
Keyword(s):  
Aortic Arch ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects

scholarly journals OC13.07: * The impact of additional anomalies on head growth in fetuses with congenital heart defects

2018 ◽  
Vol 52 ◽  
pp. 32-32
Author(s):  
A. van Nisselrooij ◽  
F.A. Jansen ◽  
N. van Geloven ◽  
I. Linskens ◽  
E. Pajkrt ◽  
...  
Keyword(s):  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Head Growth ◽  
The Impact

scholarly journals OC12.05: Head growth in newborns with prenatally diagnosed congenital heart defects

2014 ◽  
Vol 44 (S1) ◽  
pp. 31-31
Author(s):  
S. Brun ◽  
J. Stirnemann ◽  
M. Levy ◽  
L.J. Salomon ◽  
Y. Ville
Keyword(s):  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Head Growth

Balancing pulmonary and systemic arterial flows in parallel circulations: the value of monitoring system venous oxygen saturations

1997 ◽  
Vol 7 (1) ◽  
pp. 74-79 ◽  
Author(s):  
Christopher J. Riordan ◽  
Flemming Randsbaek ◽  
John H. Storey ◽  
William D. Montgomery ◽  
William P. Santamore ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Congenital Heart Defects ◽  
Oxygen Delivery ◽  
Congenital Heart ◽  
Heart Defects ◽  
Arterial Oxygen Saturation ◽  
Limited Range ◽  
Arterial Oxygen ◽  
Flow Ratio ◽  
Venous Oxygen Saturation

AbstractAccurate bedside assessment of the ratio of pulmonary to systemic flow (Qp/Qs ratio, referred to as “the flow ratio” or “the ratio”) plays an important role in the management of many congenital heart defects, especially the complexes unified by univentricular atrioventricular connections. Arterial oxygen saturation can be a misleading measure of the ratio, and may not reflect derangements until they are quite large. Theoretical analysis suggests that systemic venous oxygenation may be a better indicator of the ratio. To examine this, we created a widely patent atrial septal defect in neonatal piglets (weight =4–6.5 kg, n=6). Snares aruond the aorta and pulmonary trunk were adjusted to alter the flow ratio from 0.1 to 6.5. Venous oxygen saturations, measured in the mid-inferior caval vein, were at a maximum at a ratio about 1, and declined rapidly with increases or decreases in the ratio beyond a limited range. The venous oxygen saturation was found to vary much more than arterial oxygen saturation, with arterial oxygen saturation only falling when the ratio dropped below 0.5. Oxygen delivery (Oxygen Content x Cardiacoutput) was found to parallel closely systemic venous oxygen saturation, and was at a maximum at the same ratio that produced a maximum value of systemic venous oxygen saturation. The study suggests that systemic venous oxygen saturation provides a better estimate than does systemic arterial oxygen saturationof the flow ratio and oxygen delivery. Interventions that maximize systemic venous oxygen saturation should maximize oxygen delivery, and determination of systemic venous oxygen saturation should be a helpful addition in managing children with a number of congenital heart defects.

scholarly journals Unexpected death in children with severe congenital heart defects in Norway 2004–2016

2021 ◽  
pp. archdischild-2020-319936
Author(s):  
Gunnar Wik ◽  
Jarle Jortveit ◽  
Vasileios Sitras ◽  
Gaute Døhlen ◽  
Arild E Rønnestad ◽  
...  
Keyword(s):  
Oxygen Saturation ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Low Oxygen ◽  
Clinical Registry ◽  
Cardiac Intervention ◽  
Cardiac Defects ◽  
Staged Surgery

AimsUpdated knowledge on the rates and causes of death among children with severe congenital heart defects (CHDs) is needed to further improve treatment and survival. This study investigated nationwide mortality rates in children with severe CHDs with an emphasis on unexpected mortality unrelated to cardiac intervention.Methods and resultsData on all pregnancies and live-born children in Norway from 2004 to 2016 were obtained from national registries, the Oslo University Hospital’s Clinical Registry for CHDs and medical records. Among 2359 live-born children with severe CHDs, 234 (10%) died before 2 years of age. Of these, 109 (46%) died in palliative care, 58 (25%) died of causes related to a cardiac intervention and 67 (29%) died unexpectedly and unrelated to a cardiac intervention, either before (n=26) or following (n=41) discharge after a cardiac intervention. Comorbidity (38/67, 57%), persistent low oxygen saturation (SaO2; <95%; 41/67, 61%), staged surgery (21/41, 51%), residual cardiac defects (22/41, 54%) and infection (36/67, 54%) were frequent in children who died unexpectedly unrelated to an intervention. Two or more of these factors were present in 62 children (93%). The medical reports at hospital discharge lacked information on follow-up in many patients who died unexpectedly.ConclusionsThe numbers of unexpected deaths unrelated to cardiac intervention in children <2 years of age without comorbidity were low in Norway. However, close follow-up is recommended for infants with comorbidities, persistent low oxygen saturation, staged surgery or residual cardiac defects, particularly when an infection occurs.

scholarly journals Tips and Tricks in Cardiac Surgical Anesthesia

2022 ◽  
Vol 4 (1) ◽  
pp. 01-02
Author(s):  
Hakan Gokalp TAS ◽  
Hüsnü Degirmenci
Keyword(s):  
Coronary Artery ◽  
Heart Transplantation ◽  
Heart Valve ◽  
Congenital Heart Defects ◽  
Congenital Heart ◽  
Heart Defects ◽  
Ascending Aorta ◽  
Tips And Tricks ◽  
Valve Repair ◽  
Anesthesia Management

For operations including coronary artery by-pass grafting (CABG), heart valve repair or replacement, ascending aorta surgeries, heart transplantation, and surgical correction of congenital heart defects, anesthesia management shares many similar concepts

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