Testing for enzootic abortion of ewes

2021 ◽  
Vol 188 (8) ◽  
pp. 314-315
Author(s):  
Katherine Timms

Pathogens ◽  
2021 ◽  
Vol 10 (5) ◽  
pp. 543
Author(s):  
Sergio Gastón Caspe ◽  
Javier Palarea-Albaladejo ◽  
Clare Underwood ◽  
Morag Livingstone ◽  
Sean Ranjan Wattegedera ◽  
...  

Chlamydia abortus infects livestock species worldwide and is the cause of enzootic abortion of ewes (EAE). In Europe, control of the disease is achieved using a live vaccine based on C. abortus 1B strain. Although the vaccine has been useful for controlling disease outbreaks, abortion events due to the vaccine have been reported. Recently, placental pathology resulting from a vaccine type strain (vt) infection has been reported and shown to be similar to that resulting from a natural wild-type (wt) infection. The aim of this study was to extend these observations by comparing the distribution and severity of the lesions, the composition of the predominating cell infiltrate, the amount of bacteria present and the role of the blood supply in infection. A novel system for grading the histological and pathological features present was developed and the resulting multi-parameter data were statistically transformed for exploration and visualisation through a tailored principal component analysis (PCA) to evaluate the difference between them. The analysis provided no evidence of meaningful differences between vt and wt strains in terms of the measured pathological parameters. The study also contributes a novel methodology for analysing the progression of infection in the placenta for other abortifacient pathogens.



Vaccine ◽  
1989 ◽  
Vol 7 (2) ◽  
pp. 178
Author(s):  
Annie Rodolakis ◽  
Françoise Bernard ◽  
Armel Souriau


1988 ◽  
Vol 123 (15) ◽  
pp. 399-400 ◽  
Author(s):  
K. Morgan ◽  
J. Wills ◽  
P. Howard ◽  
R. Williams


1990 ◽  
Vol 126 (6) ◽  
pp. 136-138 ◽  
Author(s):  
ID Aitken ◽  
MJ Clarkson ◽  
K Linklater


2019 ◽  
Vol 185 (5) ◽  
pp. 137-138 ◽  

This focus article has been prepared by Amanda Carson and Rudolf Reichel of the APHA Small Ruminant Species Expert Group and Maggie He, data analyst at the APHA Surveillance Intelligence Unit.



1983 ◽  
Vol 113 (18) ◽  
pp. 413-414 ◽  
Author(s):  
F. Johnson ◽  
M. Clarkson ◽  
W. Spencer


Nature ◽  
1964 ◽  
Vol 203 (4949) ◽  
pp. 1088-1089 ◽  
Author(s):  
M. J. STUDDERT ◽  
P. C. KENNEDY


2013 ◽  
Vol 195 (2) ◽  
pp. 257-259 ◽  
Author(s):  
David Longbottom ◽  
Gary Entrican ◽  
Nicholas Wheelhouse ◽  
Helen Brough ◽  
Catherine Milne




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