Spatial controls for growth zone formation during the fission yeast cell cycle

Yeast ◽  
2008 ◽  
Vol 25 (1) ◽  
pp. 59-69 ◽  
Author(s):  
Attila Csikász-Nagy ◽  
Béla Győrffy ◽  
Wolfgang Alt ◽  
John J. Tyson ◽  
Béla Novák
Keyword(s):  
Cell Cycle ◽  
Yeast Cell ◽  
Fission Yeast ◽  
Growth Zone ◽  
Yeast Cell Cycle ◽  
Zone Formation ◽  
Fission Yeast Cell

Cyclin Dependent Kinases and Regulation of the Fission Yeast Cell Cycle

1999 ◽  
Vol 380 (7-8) ◽  
pp. 729-733 ◽  
Author(s):  
P. Nurse
Keyword(s):  
Cell Cycle ◽  
Yeast Cell ◽  
Fission Yeast ◽  
S Phase ◽  
Yeast Cell Cycle ◽  
Cyclin Dependent Kinases ◽  
Fission Yeast Cell ◽  
Nutritional Deprivation ◽  
Orderly Fashion ◽  
A Cell

AbstractThe cyclin dependent kinases (CDKs), formed by complexes between Cdc2p and the B-cyclins Cig2p and Cdc13p, have a central role in regulating the fission yeast cell cycle and maintaining genomic stability. The CDK Cig2p/Cdc2p controls the onset of S-phase and the CDK Cdc13p/Cdc2p controls the onset of mitosis and ensures that there is only one S-phase in each cell. Cdc13p/Cdc2p can replace Cig2p/Cdc2p for the onset of S-phase, suggesting that the increasing activity of a single CDK during the cell cycle is sufficient to drive a cell in an orderly fashion into S-phase and into mitosis. If S-phase is incomplete, then inhibition of Cdc13p/Cdc2p prevents cells with unreplicated DNA from undergoing a catastrophic entry into mitosis. Control of CDK activity is also important to allow cells to exit the cell cycle and accumulate in G1 in response to nutritional deprivation and the presence of pheromone.

The fission yeast cell cycle control gene cdc2: structure of the cdc2 region

1985 ◽  
Vol 201 (3) ◽  
pp. 543-545 ◽  
Author(s):  
Barbara Durkacz ◽  
David Beach ◽  
Jacqueline Hayles ◽  
Paul Nurse
Keyword(s):  
Cell Cycle ◽  
Yeast Cell ◽  
Fission Yeast ◽  
Cell Cycle Control ◽  
Yeast Cell Cycle ◽  
Control Gene ◽  
Fission Yeast Cell

scholarly journals The informational architecture of the cell

2016 ◽  
Vol 374 (2063) ◽  
pp. 20150057 ◽  
Author(s):  
Sara Imari Walker ◽  
Hyunju Kim ◽  
Paul C. W. Davies
Keyword(s):  
Cell Cycle ◽  
Information Processing ◽  
Yeast Cell ◽  
Fission Yeast ◽  
Biological Networks ◽  
Yeast Cell Cycle ◽  
Random Networks ◽  
Scale Free ◽  
Fission Yeast Cell ◽  
Information Measures

We compare the informational architecture of biological and random networks to identify informational features that may distinguish biological networks from random. The study presented here focuses on the Boolean network model for regulation of the cell cycle of the fission yeast Schizosaccharomyces pombe . We compare calculated values of local and global information measures for the fission yeast cell cycle to the same measures as applied to two different classes of random networks: Erdös–Rényi and scale-free. We report patterns in local information processing and storage that do indeed distinguish biological from random, associated with control nodes that regulate the function of the fission yeast cell-cycle network. Conversely, we find that integrated information, which serves as a global measure of ‘emergent’ information processing, does not differ from random for the case presented. We discuss implications for our understanding of the informational architecture of the fission yeast cell-cycle network in particular, and more generally for illuminating any distinctive physics that may be operative in life.

Sign in / Sign up

Export Citation Format

Share Document