High-Performance Liquid Chromatography Determination of N- and O-Demethylase Activities of Chemicals in Human Liver Microsomes: Application of Postcolumn Fluorescence Derivatization Using Nash Reagent

Kaoru Kobayashi; Tessai Yamamoto; Miwo Taguchi; Kan Chiba

doi:10.1006/abio.2000.4709

High-Performance Liquid Chromatography Determination of N- and O-Demethylase Activities of Chemicals in Human Liver Microsomes: Application of Postcolumn Fluorescence Derivatization Using Nash Reagent

Analytical Biochemistry ◽

10.1006/abio.2000.4709 ◽

2000 ◽

Vol 284 (2) ◽

pp. 342-347 ◽

Cited By ~ 10

Author(s):

Kaoru Kobayashi ◽

Tessai Yamamoto ◽

Miwo Taguchi ◽

Kan Chiba

Keyword(s):

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Human Liver ◽

High Performance ◽

Liver Microsomes ◽

Human Liver Microsomes ◽

Fluorescence Derivatization ◽

Nash Reagent

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High-performance liquid chromatography method for determination of N-glucuronidation of 4-aminobiphenyl by mouse, rat, and human liver microsomes

Analytical Biochemistry ◽

10.1016/j.ab.2005.01.048 ◽

2005 ◽

Vol 340 (2) ◽

pp. 352-358 ◽

Cited By ~ 10

Author(s):

Mustafa Al-Zoughool ◽

Glenn Talaska

Keyword(s):

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Human Liver ◽

High Performance ◽

Liver Microsomes ◽

Human Liver Microsomes ◽

Chromatography Method ◽

Liquid Chromatography Method

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Determination of Theophylline Metabolites in Human Liver Microsomes by High-Performance Liquid Chromatography

Analytical Biochemistry ◽

10.1006/abio.1994.1446 ◽

1994 ◽

Vol 222 (1) ◽

pp. 9-13 ◽

Cited By ~ 6

Author(s):

B.B. Rasmussen ◽

K.K. Nielsen ◽

K. Brosen

Keyword(s):

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Human Liver ◽

High Performance ◽

Liver Microsomes ◽

Human Liver Microsomes

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Determination of the New MDR-Modifier PFP 6 and its Metabolites in Human Liver Microsomes by High-Performance Liquid Chromatography

Biomedical Chromatography ◽

10.1002/(sici)1099-0801(199605)10:3<127::aid-bmc568>3.0.co;2-z ◽

1996 ◽

Vol 10 (3) ◽

pp. 127-130 ◽

Cited By ~ 2

Author(s):

Margit Spatzenegger ◽

Gerhard Ecker ◽

Walter Jäger

Keyword(s):

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Human Liver ◽

High Performance ◽

Liver Microsomes ◽

Human Liver Microsomes

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Methanol adducts leading to the identification of a reactive aldehyde metabolite of CPAQOP in human liver microsomes by ultra-high-performance liquid chromatography/mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.7772 ◽

2016 ◽

Vol 31 (1) ◽

pp. 145-151 ◽

Cited By ~ 1

Author(s):

Scott Martin ◽

Eva M. Lenz ◽

Robin Smith ◽

David G. Temesi ◽

Alexandra L. Orton ◽

...

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Human Liver ◽

High Performance ◽

Liver Microsomes ◽

Human Liver Microsomes ◽

Liquid Chromatography Mass Spectrometry ◽

Chromatography Mass Spectrometry ◽

Reactive Aldehyde

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Comparative metabolism of tussilagone in rat and human liver microsomes using ultra-high-performance liquid chromatography coupled with high-resolution LTQ-Orbitrap mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.7262 ◽

2015 ◽

Vol 29 (18) ◽

pp. 1641-1650 ◽

Cited By ~ 7

Author(s):

Xin-Shi Zhang ◽

Wei Ren ◽

Bao-Lin Bian ◽

Hai-Yu Zhao ◽

Shu Wang

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

High Resolution ◽

Human Liver ◽

High Performance ◽

Liver Microsomes ◽

Human Liver Microsomes ◽

Comparative Metabolism ◽

Orbitrap Mass Spectrometry

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Assay of caffeine metabolism in vitro by human liver microsomes using radio-high-performance liquid chromatography

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/0731-7085(90)80121-5 ◽

1990 ◽

Vol 8 (8-12) ◽

pp. 783-787 ◽

Cited By ~ 7

Author(s):

F. Valero ◽

R. De La Torre ◽

A.R. Boobis ◽

S. Murray ◽

J. Segura

Keyword(s):

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Human Liver ◽

High Performance ◽

Liver Microsomes ◽

Human Liver Microsomes ◽

Caffeine Metabolism

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Assay of mephenytoin metabolism in human liver microsomes by high-performance liquid chromatography

Analytical Biochemistry ◽

10.1016/0003-2697(85)90177-0 ◽

1985 ◽

Vol 151 (2) ◽

pp. 286-291 ◽

Cited By ~ 50

Author(s):

U.Thomas Meier ◽

Thomas Kronbach ◽

Urs A. Meyer

Keyword(s):

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Human Liver ◽

High Performance ◽

Liver Microsomes ◽

Human Liver Microsomes

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Rapid and Simple Method to Determine Tamoxifen and Its Major Metabolites in Human Liver Microsomes by High Performance Liquid Chromatography with Fluorescence Detection

Analytical Letters ◽

10.1080/00032719808005285 ◽

1998 ◽

Vol 31 (12) ◽

pp. 2067-2076 ◽

Cited By ~ 6

Author(s):

O. Merle ◽

J. Guitton ◽

M D Burke ◽

M Ollagnier

Keyword(s):

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Fluorescence Detection ◽

Human Liver ◽

High Performance ◽

Liver Microsomes ◽

Human Liver Microsomes ◽

Simple Method

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Comparative metabolism of four limonoids in human liver microsomes using ultra-high-performance liquid chromatography coupled with high-resolution LTQ-Orbitrap mass spectrometry

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.7365 ◽

2015 ◽

Vol 29 (21) ◽

pp. 2045-2056 ◽

Cited By ~ 15

Author(s):

Wei Ren ◽

Shao-Kun Xin ◽

Ling-Yu Han ◽

Ran Zuo ◽

Yan Li ◽

...

Keyword(s):

Mass Spectrometry ◽

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

High Resolution ◽

Human Liver ◽

High Performance ◽

Liver Microsomes ◽

Human Liver Microsomes ◽

Comparative Metabolism ◽

Orbitrap Mass Spectrometry

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Simultaneous Determination of Fluvoxamine and Its Metabolites in Human Liver Microsomes by High‐Performance Liquid Chromatography with Solid‐Phase Extraction

Analytical Letters ◽

10.1080/00032710600822825 ◽

2006 ◽

Vol 39 (12) ◽

pp. 2405-2415 ◽

Cited By ~ 1

Author(s):

Masatomo Miura ◽

Tadashi Ohkubo

Keyword(s):

High Performance Liquid Chromatography ◽

Liquid Chromatography ◽

Solid Phase Extraction ◽

Simultaneous Determination ◽

Human Liver ◽

High Performance ◽

Solid Phase ◽

Liver Microsomes ◽

Phase Extraction

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