The Nonactive Site Cysteine Residues of Yeast Protein Disulfide Isomerase Are Not Required for Cell Viability

1998 ◽  
Vol 248 (3) ◽  
pp. 621-627 ◽  
Author(s):  
José M. Luz ◽  
William J. Lennarz
Keyword(s):  
Cell Viability ◽  
Protein Disulfide Isomerase ◽  
Cysteine Residues ◽  
Yeast Protein ◽  
Disulfide Isomerase ◽  
Protein Disulfide

scholarly journals PDI Family Members as Guides for Client Folding and Assembly

2020 ◽  
Vol 21 (24) ◽  
pp. 9351
Author(s):  
Shingo Kanemura ◽  
Motonori Matsusaki ◽  
Kenji Inaba ◽  
Masaki Okumura
Keyword(s):  
Endoplasmic Reticulum ◽  
Cell Viability ◽  
Molecular Chaperones ◽  
Protein Disulfide Isomerase ◽  
Family Members ◽  
Secretory Proteins ◽  
Efficient Production ◽  
Protein Homeostasis ◽  
Disulfide Isomerase ◽  
Protein Disulfide

Complicated and sophisticated protein homeostasis (proteostasis) networks in the endoplasmic reticulum (ER), comprising disulfide catalysts, molecular chaperones, and their regulators, help to maintain cell viability. Newly synthesized proteins inserted into the ER need to fold and assemble into unique native structures to fulfill their physiological functions, and this is assisted by protein disulfide isomerase (PDI) family. Herein, we focus on recent advances in understanding the detailed mechanisms of PDI family members as guides for client folding and assembly to ensure the efficient production of secretory proteins.

Functional differences between human and yeast protein disulfide isomerase family proteins

2004 ◽  
Vol 320 (2) ◽  
pp. 359-365 ◽  
Author(s):  
Taiji Kimura ◽  
Yasuhiro Hosoda ◽  
Yukiko Kitamura ◽  
Hideshi Nakamura ◽  
Tomohisa Horibe ◽  
...  
Keyword(s):  
Protein Disulfide Isomerase ◽  
Yeast Protein ◽  
Disulfide Isomerase ◽  
Functional Differences ◽  
Protein Disulfide ◽  
Protein Disulfide Isomerase Family

scholarly journals The b’x Region of Yeast Protein Disulfide Isomerase is Not Essential for Saccharomyces cerevisiae Viability at 30 °C

2009 ◽  
Vol 3 (1) ◽  
pp. 27-32
Author(s):  
PURKAN PURKAN ◽  
LALU RUDYAT TELLY SAVALAS ◽  
MULIAWATI SINDUMARTA ◽  
DESSY NATALIA
Keyword(s):  
Saccharomyces Cerevisiae ◽  
Protein Disulfide Isomerase ◽  
Yeast Protein ◽  
Disulfide Isomerase ◽  
Protein Disulfide
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