Rapid Inactivation of HIV-1 in Single Donor Preparations of Human Fresh Frozen Plasma by Methylene Blue/Light Treatment

Biologicals ◽  
1994 ◽  
Vol 22 (3) ◽  
pp. 227-231 ◽  
Author(s):  
Bernd Lambrecht ◽  
Stephen G. Norley ◽  
Reinhard Kurth ◽  
Harald Mohr
Transfusion ◽  
1994 ◽  
Vol 34 (8) ◽  
pp. 685-689 ◽  
Author(s):  
T Zeiler ◽  
H Riess ◽  
G Wittmann ◽  
G Hintz ◽  
R Zimmermann ◽  
...  

1985 ◽  
Vol 40 (4) ◽  
pp. 385-387 ◽  
Author(s):  
Arthur Dresdale ◽  
Frederick O. Bowman ◽  
James R. Malm ◽  
Keith Reemtsma ◽  
Craig R. Smith ◽  
...  

Vox Sanguinis ◽  
2000 ◽  
Vol 79 (3) ◽  
pp. 156-160 ◽  
Author(s):  
J.A. Aznar ◽  
S. Bonanad ◽  
J.M. Montoro ◽  
C. Hurtado ◽  
A.R. Cid ◽  
...  

2020 ◽  
pp. 49-60
Author(s):  
Ivan Krivov ◽  
Aligejdar Ragimov ◽  
Emin Salimov ◽  
Karim Magadeev ◽  
Yana Mishutkina

The article presents research data on the conservation of coagulation potential of lyophilized plasma inactivated by three different technologies — amotosalen and ultraviolet irradiation of spectrum A, riboflavin + ultraviolet of spectrum B, methylene blue + visible light. The study analyzed the concentration of blood-coagulation factors that affect the extrinsic, intrinsic and general coagulation pathways by comparing samples of virus-inactivated lyophilized plasma with various inactivation methods. As a result of the study, no significant differences in the indices between samples of plasma inactivated by various methods were detected. Therefore, virus-inactivated lyophilized plasma can serve as a full alternative to fresh frozen plasma.


Vox Sanguinis ◽  
2007 ◽  
Vol 0 (0) ◽  
pp. 070305073756002-???
Author(s):  
C. Politis ◽  
L. Kavallierou ◽  
S. Hantziara ◽  
P. Katsea ◽  
V. Triantaphylou ◽  
...  

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