Changes of Nuclear Protein Kinase C Activity and Isotype Composition in PC12 Cell Proliferation and Differentiation

1996 ◽  
Vol 224 (1) ◽  
pp. 72-78 ◽  
Author(s):  
Paola Borgatti ◽  
Meri Mazzoni ◽  
Cinzia Carini ◽  
Luca Maria Neri ◽  
Marco Marchisio ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Protein Kinase C ◽  
Protein Kinase ◽  
Pc12 Cell ◽  
Nuclear Protein ◽  
Kinase C ◽  
Protein Kinase C Activity ◽  
Cell Proliferation And Differentiation ◽  
Proliferation And Differentiation

Protein Kinase C in Cell Proliferation and Differentiation

1988 ◽  
Vol 551 (1 Membrane in C) ◽  
pp. 369-371 ◽  
Author(s):  
SERGIO ADAMO ◽  
CLARA NERVI ◽  
ROBERTA CECI ◽  
LUCIANA DE ANGELIS ◽  
MARIO MOLINARO
Keyword(s):  
Cell Proliferation ◽  
Protein Kinase C ◽  
Protein Kinase ◽  
Kinase C ◽  
Cell Proliferation And Differentiation ◽  
Proliferation And Differentiation

Dietary Fibers and Fats Alter Rat Colon Protein Kinase C Activity: Correlation to Cell Proliferation

1993 ◽  
Vol 123 (4) ◽  
pp. 649-655 ◽  
Author(s):  
Robert S. Chapkin ◽  
Jian Gao ◽  
Dong-Yeon K. Lee ◽  
Joanne R. Lupton
Keyword(s):  
Cell Proliferation ◽  
Protein Kinase C ◽  
Protein Kinase ◽  
Rat Colon ◽  
Dietary Fibers ◽  
Kinase C ◽  
Protein Kinase C Activity

Protein kinase C: a target for anticancer drugs?

2003 ◽  
pp. 389-396 ◽  
Author(s):  
H J Mackay ◽  
C J Twelves
Keyword(s):  
Protein Kinase C ◽  
Protein Kinase ◽  
Anticancer Therapy ◽  
Kinase C ◽  
Cell Proliferation And Differentiation ◽  
Selective Targeting ◽  
Proliferation And Differentiation ◽  
Tumour Cell Invasion ◽  
Suitable Target

Protein kinase C (PKC) is a family of serine/threonine kinases that is involved in the transduction of signals for cell proliferation and differentiation. The important role of PKC in processes relevant to neoplastic transformation, carcinogenesis and tumour cell invasion renders it a potentially suitable target for anticancer therapy. Furthermore, there is accumulating evidence that selective targeting of PKC may improve the therapeutic efficacy of established neoplastic agents and sensitise cells to ionising radiation. This article reviews the rationale for targeting PKC, focuses on its role in breast cancer and reviews the preclinical and clinical data available for the efficacy of PKC inhibition.

Effect of dietary phytosterols on cell proliferation and protein kinase C activity in rat colonic mucosa

1997 ◽  
Vol 27 (2) ◽  
pp. 210-215 ◽  
Author(s):  
Atif B. Awad ◽  
Ana Y. Tagle Hernandez ◽  
Carol S. Fink ◽  
Sandra L. Mendel
Keyword(s):  
Cell Proliferation ◽  
Protein Kinase C ◽  
Protein Kinase ◽  
Colonic Mucosa ◽  
Kinase C ◽  
Protein Kinase C Activity
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