Fibulin-2 (FBLN2): Human cDNA Sequence, mRNA Expression, and Mapping of the Gene on Human and Mouse Chromosomes

Genomics ◽  
1994 ◽  
Vol 22 (2) ◽  
pp. 425-430 ◽  
Author(s):  
Rui-Zhu Zhang ◽  
Te-Cheng Pan ◽  
Zong-Yu Zhang ◽  
Marie-Geneviève Mattei ◽  
Rupert Timpl ◽  
...  
1986 ◽  
Vol 261 (34) ◽  
pp. 16082-16086 ◽  
Author(s):  
D Landsman ◽  
T Srikantha ◽  
R Westermann ◽  
M Bustin

1999 ◽  
Vol 344 (3) ◽  
pp. 953-960 ◽  
Author(s):  
Giuseppe FIERMONTE ◽  
Vincenza DOLCE ◽  
Roberto ARRIGONI ◽  
Michael J. RUNSWICK ◽  
John E. WALKER ◽  
...  

The dicarboxylate carrier (DIC) is a nuclear-encoded protein located in the mitochondrial inner membrane. It catalyses the transport of dicarboxylates such as malate and succinate across the mitochondrial membrane in exchange for phosphate, sulphate and thiosulphate. We have determined the sequences of the human cDNA and gene for the DIC. The gene sequence was established from overlapping genomic clones generated by PCRs by use of primers and probes based upon the human cDNA sequence. It is spread over 8.6 kb of human DNA and is divided into 11 exons. Five short interspersed repetitive Alu sequences are found in intron I. The protein encoded by the gene is 287 amino acids long. In common with the rat protein, it does not have a processed presequence to help to target it into mitochondria. It has been demonstrated by Northern- and Western-blot analyses that the DIC is present in high amounts in liver and kidney, and at lower levels in all the other tissues analysed. The positions of introns contribute towards an understanding of the processes involved in the evolution of human genes for carrier proteins.


1989 ◽  
Vol 17 (15) ◽  
pp. 6390-6390 ◽  
Author(s):  
Deborah K. Dunn ◽  
David D. Howells ◽  
Jane P. Richardson ◽  
Peter S. Goldfarb

1990 ◽  
Vol 18 (3) ◽  
pp. 681-681 ◽  
Author(s):  
G. Slynn ◽  
D. Jenner ◽  
W. Potts ◽  
J.E.N. Morten ◽  
A.F. Markham

IUBMB Life ◽  
1997 ◽  
Vol 43 (3) ◽  
pp. 669-675
Author(s):  
Jae Wha Kim ◽  
Younghee Lee ◽  
Ho Bum Kang ◽  
Yong Kyung Choe ◽  
Tae Wha Chung ◽  
...  

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