Uterine Malignant Mixed Mullerian Tumor in a Patient on Long-Term Tamoxifen Therapy for Breast Cancer

1993 ◽  
Vol 51 (3) ◽  
pp. 411-415 ◽  
Author(s):  
Martha R. Clarke
Keyword(s):  
Breast Cancer ◽  
Tamoxifen Therapy ◽  
Malignant Mixed Mullerian Tumor ◽  
Malignant Mixed Müllerian Tumor ◽  
Mixed Müllerian Tumor ◽  
Mixed Mullerian Tumor ◽  
Mullerian Tumor

Is there an association between long-term tamoxifen treatment and the development of carcinosarcoma (malignant mixed Müllerian tumor) of the uterus?

1995 ◽  
Vol 5 (4) ◽  
pp. 310-313 ◽  
Author(s):  
M. J. Evans ◽  
I. D. Miller ◽  
N. E.I. Langlois ◽  
H. C. Kitchener
Keyword(s):  
Tamoxifen Therapy ◽  
Tamoxifen Treatment ◽  
Uterine Carcinosarcoma ◽  
Malignant Mixed Mullerian Tumor ◽  
Malignant Mixed Müllerian Tumor ◽  
History Of ◽  
Mixed Müllerian Tumor ◽  
Mixed Mullerian Tumor ◽  
Mullerian Tumor

A cluster of five patients with endometrial carcinosarcoma (malignant mixed Müllerian tumor) occurred at our center during 1993; four of these had been prescribed long-term tamoxifen for breast carcinoma. Searching the archives for the 9-year period 1983–1992 revealed two further cases of uterine carcinosarcoma occurring in patients prescribed tamoxifen, from a total of 16 cases of this tumor. Five of the six patients diagnosed with carcinosarcoma who had been taking tamoxifen had been maintained on the drug for at least 6 years, while the other had a 3-year history of tamoxifen therapy. From these data we raise the question of an association between long-term tamoxifen treatment and development of endometrial carcinosarcoma, following the dramatic increase in the prescribing of this drug after 1984.

scholarly journals A Case of Uterine Carcinosarcoma Detected Simultaneously with Breast and Colon Cancer (Triple Primary Malignant Tumor)

2018 ◽  
Vol 11 (2) ◽  
pp. 431-435 ◽  
Author(s):  
Eunhyun Lee ◽  
Yong-Il Ji
Keyword(s):  
Breast Cancer ◽  
Colon Cancer ◽  
Malignant Tumor ◽  
Uterine Carcinosarcoma ◽  
Primary Malignant Tumor ◽  
Malignant Mixed Mullerian Tumor ◽  
Malignant Mixed Müllerian Tumor ◽  
Mixed Müllerian Tumor ◽  
Mixed Mullerian Tumor ◽  
Mullerian Tumor

Uterine carcinosarcoma, also known as malignant mixed Mullerian tumor of the uterus, is rare and rarely diagnosed simultaneously with cancers in other organs. We report a case of a 63-year-old woman who was simultaneously diagnosed with uterine carcinosarcoma, breast cancer, and colon cancer.

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