Applications of Sensitivity Analysis to a Physiologically Based Pharmacokinetic Model for Carbon Tetrachloride in Rats

Toxicology and Applied Pharmacology ◽

10.1006/taap.1994.1177 ◽

1994 ◽

Vol 128 (1) ◽

pp. 36-44 ◽

Author(s):

M.V. Evans ◽

W.D. Crank ◽

H.M. Yang ◽

J.E. Simmons

Keyword(s):

Sensitivity Analysis ◽

Carbon Tetrachloride ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

A physiologically based pharmacokinetic model for inhaled carbon tetrachloride

Toxicology and Applied Pharmacology ◽

10.1016/0041-008x(88)90080-4 ◽

1988 ◽

Vol 96 (2) ◽

pp. 191-211 ◽

Author(s):

Dennis J. Paustenbach ◽

Harvey J. Clewell ◽

Michael L. Gargas ◽

Melvin E. Andersen

Keyword(s):

Carbon Tetrachloride ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

The application of global sensitivity analysis in the development of a physiologically based pharmacokinetic model for m-xylene and ethanol co-exposure in humans

Frontiers in Pharmacology ◽

10.3389/fphar.2015.00135 ◽

2015 ◽

Vol 6 ◽

Author(s):

George D. Loizou ◽

Kevin McNally ◽

Kate Jones ◽

John Cocker

Keyword(s):

Sensitivity Analysis ◽

Pharmacokinetic Model ◽

Global Sensitivity Analysis ◽

Physiologically Based Pharmacokinetic Model ◽

Global Sensitivity ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Sensitivity Analysis of a Physiologically Based Pharmacokinetic Model Used for Treatment Planning in Peptide Receptor Radionuclide Therapy

Cancer Biotherapy & Radiopharmaceuticals ◽

10.1089/cbr.2016.2012 ◽

2016 ◽

Vol 31 (6) ◽

pp. 217-224 ◽

Author(s):

Deni Hardiansyah ◽

Nusrat Jihan Begum ◽

Peter Kletting ◽

Felix M. Mottaghy ◽

Gerhard Glatting

Keyword(s):

Sensitivity Analysis ◽

Treatment Planning ◽

Radionuclide Therapy ◽

Pharmacokinetic Model ◽

Peptide Receptor Radionuclide Therapy ◽

Physiologically Based Pharmacokinetic Model ◽

Peptide Receptor ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Important pharmacokinetic parameters for individualization of 177 Lu‐PSMA therapy: A global sensitivity analysis for a physiologically‐based pharmacokinetic model

Medical Physics ◽

10.1002/mp.14622 ◽

2020 ◽

Author(s):

Deni Hardiansyah ◽

Peter Kletting ◽

Nusrat J. Begum ◽

Matthias Eiber ◽

Ambros J. Beer ◽

...

Keyword(s):

Sensitivity Analysis ◽

Pharmacokinetic Model ◽

Global Sensitivity Analysis ◽

Pharmacokinetic Parameters ◽

Physiologically Based Pharmacokinetic Model ◽

Global Sensitivity ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Evaluation of a Carbon Tetrachloride Physiologically Based Pharmacokinetic Model Using Real-Time Breath-Analysis Monitoring of the Rat

Inhalation Toxicology ◽

10.3109/08958379609005433 ◽

1996 ◽

Vol 8 (3) ◽

pp. 251-261 ◽

Author(s):

K. D. Thrall ◽

D. V. Kenny

Keyword(s):

Carbon Tetrachloride ◽

Real Time ◽

Pharmacokinetic Model ◽

Breath Analysis ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Physiologically based pharmacokinetic model development for trazodone: application to paediatric dose projection

10.26226/morressier.5971be87d462b80290b534f2 ◽

2017 ◽

Author(s):

F. Calisti

Keyword(s):

Pharmacokinetic Model ◽

Model Development ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Paediatric Dose

Download Full-text

Risk Assessment of Perfluorooctane Sulfonate (PFOS) using Dynamic Age Dependent Physiologically based Pharmacokinetic Model (PBPK) across human lifetime

Environmental Research ◽

10.1016/j.envres.2021.111287 ◽

2021 ◽

pp. 111287

Author(s):

Deepika Deepika ◽

Raju Prasad Sharma ◽

Marta Schuhmacher ◽

Vikas Kumar

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Perfluorooctane Sulfonate ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based ◽

Download Full-text

Human risk assessment of di-isobutyl phthalate through the application of a developed physiologically based pharmacokinetic model of di-isobutyl phthalate and its major metabolite mono-isobutyl phthalate

Archives of Toxicology ◽

10.1007/s00204-021-03057-5 ◽

2021 ◽

Author(s):

Seung-Hyun Jeong ◽

Ji-Hun Jang ◽

Hea-Young Cho ◽

Yong-Bok Lee

Keyword(s):

Risk Assessment ◽

Pharmacokinetic Model ◽

Major Metabolite ◽

Physiologically Based Pharmacokinetic Model ◽

Human Risk Assessment ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Physiologically‐Based Pharmacokinetic Model for Alectinib, Ruxolitinib, and Panobinostat in The Presence of Cancer, Renal Impairment, and Hepatic Impairment

Biopharmaceutics & Drug Disposition ◽

10.1002/bdd.2282 ◽

2021 ◽

Author(s):

Mo'tasem M. Alsmadi

Keyword(s):

Renal Impairment ◽

Hepatic Impairment ◽

Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic Model ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

Download Full-text

Development of a Physiologically-Based Pharmacokinetic Model for Perchloroethylene Using Tissue Concentration-Time Data

Toxicology and Applied Pharmacology ◽

10.1006/taap.1994.1179 ◽

1994 ◽

Vol 128 (1) ◽

pp. 50-59 ◽

Author(s):

C.E. Dallas ◽

X.M. Chen ◽

K. Obarr ◽

S. Muralidhara ◽

P. Varkonyi ◽

...

Keyword(s):

Pharmacokinetic Model ◽

Tissue Concentration ◽

Physiologically Based Pharmacokinetic Model ◽

Time Data ◽

Physiologically Based Pharmacokinetic ◽

Concentration Time ◽

Physiologically Based

Download Full-text