Statistical Shape Analysis Using Fixed Topology Skeletons: Corpus Callosum Study

1999 ◽  
pp. 382-387 ◽  
Author(s):  
Polina Golland ◽  
W. Eric L. Grimson ◽  
Ron Kikinis
Keyword(s):  
Corpus Callosum ◽  
Shape Analysis ◽  
Statistical Shape Analysis ◽  
Statistical Shape ◽  
Fixed Topology

Deformation-based Statistical Shape Analysis of the Corpus Callosum in Mild Cognitive Impairment and Alzheimer’s Disease

2018 ◽  
Vol 15 (12) ◽  
pp. 1151-1160 ◽  
Author(s):  
Zihan Jiang ◽  
Huilin Yang ◽  
Xiaoying Tang
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Cognitive Impairment ◽  
Mild Cognitive Impairment ◽  
Corpus Callosum ◽  
Shape Analysis ◽  
Disease Assessment ◽  
Statistical Shape Analysis ◽  
Superior Part ◽  
Statistical Shape

Objective: In this study, we investigated the influence that the pathology of Alzheimer’s disease (AD) exerts upon the corpus callosum (CC) using a total of 325 mild cognitive impairment (MCI) subjects, 155 AD subjects, and 185 healthy control (HC) subjects. Method: Regionally-specific morphological CC abnormalities, as induced by AD, were quantified using a large deformation diffeomorphic metric curve mapping based statistical shape analysis pipeline. We also quantified the association between the CC shape phenotype and two cognitive measures; the Mini Mental State Examination (MMSE) and the Alzheimer’s Disease Assessment Scale-Cognitive Behavior Section (ADAS-cog). To identify AD-relevant areas, CC was sub-divided into three subregions; the genu, body, and splenium (gCC, bCC, and sCC). Results: We observed significant shape compressions in AD relative to that in HC, mainly concentrated on the superior part of CC, across all three sub-regions. The HC-vs-MCI shape abnormalities were also concentrated on the superior part, but mainly occurred on bCC and sCC. The significant MCI-vs-AD shape differences, however, were only detected in part of sCC. In the shape-cognition association, significant negative correlations to ADAS-cog were detected for shape deformations at regions belonging to gCC and sCC and significant positive correlations to MMSE at regions mainly belonging to sCC. Conclusion: Our results suggest that the callosal shape deformation patterns, especially those of sCC, linked tightly to the cognitive decline in AD, and are potentially a powerful biomarker for monitoring the progression of AD.

A Riemannian Framework for Statistical Shape Analysis of the Corpus Callosum.

NeuroImage ◽  
2009 ◽  
Vol 47 ◽  
pp. S123
Author(s):  
SH Joshi ◽  
KL Narr ◽  
RP Woods ◽  
OR Phillips ◽  
KH Nuechterlein ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Shape Analysis ◽  
Statistical Shape Analysis ◽  
Statistical Shape ◽  
Riemannian Framework

scholarly journals Detecting the Shape Differences of the Corpus Callosum in Behçet's Disease by Statistical Shape Analysis

2011 ◽  
Vol 294 (5) ◽  
pp. 870-874 ◽  
Author(s):  
Cemil Colak ◽  
Ilker Ercan ◽  
Metin Dogan ◽  
Senem Turan Ozdemir ◽  
Serpil Sener ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Behçet’S Disease ◽  
Shape Analysis ◽  
Behcet’S Disease ◽  
Behçet's Disease ◽  
Statistical Shape Analysis ◽  
Behcet's Disease ◽  
Statistical Shape

scholarly journals Statistical shape analysis of the corpus callosum in Schizophrenia

NeuroImage ◽  
2013 ◽  
Vol 64 ◽  
pp. 547-559 ◽  
Author(s):  
Shantanu H. Joshi ◽  
Katherine L. Narr ◽  
Owen R. Philips ◽  
Keith H. Nuechterlein ◽  
Robert F. Asarnow ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Shape Analysis ◽  
Statistical Shape Analysis ◽  
Statistical Shape

Statistical Shape Analysis of Differences in the Shape of the Corpus Callosum Between Genders

2007 ◽  
Vol 290 (7) ◽  
pp. 825-830 ◽  
Author(s):  
Senem Turan Ozdemir ◽  
Ilker Ercan ◽  
Ozdemir Sevinc ◽  
Ibrahim Guney ◽  
Gokhan Ocakoglu ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Shape Analysis ◽  
Statistical Shape Analysis ◽  
Statistical Shape

Statistical shape analysis of corpus callosum in restless leg syndrome

2020 ◽  
Vol 42 (9) ◽  
pp. 760-766
Author(s):  
Deniz Sigirli ◽  
Aygul Gunes ◽  
Senem Turan Ozdemir ◽  
Ilker Ercan ◽  
Yavuz Durmus ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Shape Analysis ◽  
Statistical Shape Analysis ◽  
Restless Leg Syndrome ◽  
Statistical Shape

Statistical Shape Analysis of the Corpus Callosum and the Cerebellum in Migraine Patients

2013 ◽  
Vol 33 (1) ◽  
pp. 200-209
Author(s):  
Deniz SIĞIRLI ◽  
Senem TURAN ÖZDEMİR ◽  
İlker ERCAN ◽  
Özlem TAŞKAPILIOĞLU ◽  
Bahattin HAKYEMEZ ◽  
...  
Keyword(s):  
Corpus Callosum ◽  
Shape Analysis ◽  
Statistical Shape Analysis ◽  
Statistical Shape

Automatic statistical shape analysis of human cerebral asymmetry in 3D MRI

NeuroImage ◽  
2009 ◽  
Vol 47 ◽  
pp. S99
Author(s):  
A Pepe ◽  
L Zhao ◽  
J Tohka ◽  
J Koikkalainen ◽  
J Hietala ◽  
...  
Keyword(s):  
Shape Analysis ◽  
Statistical Shape Analysis ◽  
3D Mri ◽  
Cerebral Asymmetry ◽  
Statistical Shape
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