Prognostication and Prediction in Anatomic Pathology: Carcinoma of the Breast as an Illustrative Model

2011 ◽  
pp. 61-93
Author(s):  
Mark R. Wick ◽  
Paul E. Swanson ◽  
Alberto M. Marchevsky
Keyword(s):  
Carcinoma Of The Breast ◽  
Anatomic Pathology

Adrenocorticotropin Production by a Mammary Carcinoma

1977 ◽  
Vol 35 ◽  
pp. 462-463
Author(s):  
K.S. McCarty ◽  
N.R. Wallace ◽  
W. Litaker ◽  
S. Wells ◽  
G. Eisenbarth
Keyword(s):  
Adrenocorticotropic Hormone ◽  
Small Cell ◽  
Hormone Production ◽  
Carcinoma Of The Breast ◽  
Ectopic Acth ◽  
Ultrastructural Studies ◽  
Subcutaneous Metastases ◽  
Ectopic Acth Production ◽  
The Right ◽  
Pituitary Carcinomas

The production of adrenocorticotropic hormone by non-pituitary carcinomas has been documented in several tumors, most frequently small cell carcinoma of the lung, islet cell carcinomas of the pancreas, thymomas and carcinoids. Electron microscopy of these tumors reveals typical membrane-limited "neurosecretory" granules. Confirmation of the granules as adrenocorticotropin (ACTH) requires the use of OsO4 as a primary fixative to give the characteristic cored granule appearance in conjunction with immunohistochemical demonstration of the hormone peptide. Because of the rarity of ectopic ACTH production by mammary carcinomas and the absence of appropriate ultrastructural studies in the two examples of such ectopic hormone production in the literature of which we are aware (1,2), we present biochemical and ultrastructural data from a carcinoma of the breast with apparent ACTH production.The patient had her primary tumor in the right breast in 1969. The tumor recurred as visceral and subcutaneous metastases in 1976 and again in 1977.

Multi-analyte tumor profiling for treatment guidance in a rare case of advanced refractory neuroendocrine carcinoma of the breast

2020 ◽  
Author(s):  
D Schaffrin Nabe ◽  
S Schuster ◽  
D Akolkar ◽  
D Patil ◽  
V Datta ◽  
...  
Keyword(s):  
Neuroendocrine Carcinoma ◽  
Rare Case ◽  
Carcinoma Of The Breast ◽  
Tumor Profiling

MR Findings of Metaplastic Carcinoma of the Breast: Case Report

2004 ◽  
Vol 50 (4) ◽  
pp. 277 ◽  
Author(s):  
Soo Ah Im ◽  
Hak Hee Kim ◽  
Song Yee Han ◽  
Youn Soo Lee
Keyword(s):  
Case Report ◽  
Metaplastic Carcinoma ◽  
Carcinoma Of The Breast

Adenoid Cystic Carcinoma of the Breast detected with Contrast-Enhanced Spectral Mammography: A Case Report

2020 ◽  
Vol 16 ◽  
Author(s):  
Yun-Chung Cheung ◽  
Shir-Hwa Ueng ◽  
Shu-Hang Ng ◽  
Wen-Lin Kuo
Keyword(s):  
Left Breast ◽  
Breast Cancers ◽  
Resonance Imaging ◽  
Carcinoma Of The Breast ◽  
Outer Quadrant ◽  
Additional Information ◽  
Adenoid Cystic ◽  
Modern Technique ◽  
Contrast Enhanced ◽  
Rim Enhancement

Background: Contrast-enhanced spectral mammogram (CESM) is a modern technique providing additional information to detect or diagnose the breast cancers. Introduction: We present a rare ACC of breast on CESM. Methods: A 49-year-old woman with surgicopathological proved ACC is reported with features on CESM, sonography and contrast-enhanced magnetic resonance imaging (CE-MRI). Results: Sonography revealed a 1.4 cm × 1.2 cm × 1 cm circumscribe round mass in the upper outer quadrant of the left breast that was diagnosed to fibroadenoma. The mammogram did not show any discernible mass, however the recombined subtracted images displayed a circumscribe mass with thin rim enhancement and enhanced internal patches that were resembling to CE-MRI. Finally, the mass was proved to ACC. Conclusion: CESM facilitates detection of an isodense cancer and provides the enhanced features for differential diagnosis. Resembling CE-MRI, CESM displayed rim enhancement and internal enhanced patches as diagnostic clues for this case of ACC.

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