Antibiotics ◽  
2021 ◽  
Vol 10 (2) ◽  
pp. 139
Author(s):  
Jens Strohäker ◽  
Sophia Bareiß ◽  
Silvio Nadalin ◽  
Alfred Königsrainer ◽  
Ruth Ladurner ◽  
...  

(1) Background: Anaerobic infections in hepatobiliary surgery have rarely been addressed. Whereas infectious complications during the perioperative phase of liver resections are common, there are very limited data on the prevalence and clinical role of anaerobes in this context. Given the risk of contaminated bile in liver resections, the goal of our study was to investigate the prevalence and outcome of anaerobic infections in major hepatectomies. (2) Methods: We retrospectively analyzed the charts of 245 consecutive major hepatectomies that were performed at the department of General, Visceral, and Transplantation Surgery of the University Hospital of Tuebingen between July 2017 and August 2020. All microbiological cultures were screened for the prevalence of anaerobic bacteria and the patients’ clinical characteristics and outcomes were evaluated. (3) Results: Of the 245 patients, 13 patients suffered from anaerobic infections. Seven had positive cultures from the biliary tract during the primary procedure, while six had positive culture results from samples obtained during the management of complications. Risk factors for anaerobic infections were preoperative biliary stenting (p = 0.002) and bile leaks (p = 0.009). All of these infections had to be treated by intervention and adjunct antibiotic treatment with broad spectrum antibiotics. (4) Conclusions: Anaerobic infections are rare in liver resections. Certain risk factors trigger the antibiotic coverage of anaerobes.


1999 ◽  
Vol 73 (7) ◽  
pp. 675-680 ◽  
Author(s):  
Mitsuru KONISHI ◽  
Kei MORI ◽  
Eiichiro YOSHIMOTO ◽  
Ken TAKAHASHI ◽  
Toshimasa MAJIMA ◽  
...  

1972 ◽  
Vol 287 (20) ◽  
pp. 1006-1010 ◽  
Author(s):  
John G. Bartlett ◽  
Vera L. Sutter ◽  
Sydney M. Finegold
Keyword(s):  

1989 ◽  
Vol 2 (3) ◽  
pp. 376-382
Author(s):  
H. Thadepalli ◽  
I. S. Bal
Keyword(s):  

1986 ◽  
Vol 8 (Supplement_5) ◽  
pp. S569-S575 ◽  
Author(s):  
John F. Reinhardt ◽  
Lynn Johnston ◽  
Peter Ruane ◽  
Caroline C. Johnson ◽  
Leslie Ingram-drake ◽  
...  

1992 ◽  
Vol 101 (1_suppl) ◽  
pp. 9-15 ◽  
Author(s):  
Itzhak Brook

Anaerobic bacteria are important pathogens in head and neck infections such as chronic otitis media, chronic sinusitis, chronic mastoiditis, head and neck abscesses, cervical adenitis, parotitis, and postoperative infection. Bacteroides sp ( Bacteroides melaninogenicus group, Bacteroides oralis, and Bacteroides fragilis group), Peptostreptococcus sp, and Fusobacterium sp predominate. The observed recent increase in the number of β-lactamase—producing strains of Bacteroides sp isolated in head and neck infections has been associated with increased failure rates of the penicillins in the management of these infections. The pathogenicity of these organisms is expressed through their ability not only to survive penicillin therapy but also to shield penicillin-susceptible pathogens from the drug. Because of these direct and indirect virulent characteristics of anaerobic bacteria, appropriate antimicrobial therapy must be directed against all pathogens in mixed infections.


Chemotherapy ◽  
1976 ◽  
pp. 303-305
Author(s):  
Haragopal Thadepalli ◽  
Jong T. Huang ◽  
Dennis G. Hooper ◽  
Albert H. Niden
Keyword(s):  

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