Nanoparticles for Pulmonary Delivery

2011 ◽  
pp. 335-366 ◽  
Author(s):  
Alan B. Watts ◽  
Robert O. Williams
Keyword(s):  
Pulmonary Delivery

Pulmonary Delivery of Triptorelin Loaded in Pluronic Based Nanomicelles in Rat Model

2018 ◽  
Vol 15 (5) ◽  
pp. 630-640 ◽  
Author(s):  
Hamed Vakilzadeh ◽  
Jaleh Varshosaz ◽  
Mohsen Minaiyan
Keyword(s):  
Rat Model ◽  
Pulmonary Delivery

Biodegradable Zwitterionic Poly(Carboxybetaine) Microgel for Sustained Delivery of Antibodies with Extended Stability and Preserved Function

Soft Matter ◽  
2021 ◽  
Author(s):  
Amir Erfani ◽  
Abanoub Hanna ◽  
Payam Zarrintaj ◽  
Saeed Manouchehri ◽  
Katie Weigandt ◽  
...  
Keyword(s):  
Monoclonal Antibodies ◽  
Pulmonary Delivery ◽  
Sustained Delivery ◽  
The Poor ◽  
Poor Stability

Many recent innovative treatments are based on monoclonal antibodies (mAbs) and other protein therapies. Nevertheless, sustained subcutaneous, oral or pulmonary delivery of such therapeutics are limited by the poor stability,...

scholarly journals Pulmonary Delivery: Innovative Approaches and Perspectives

2011 ◽  
Vol 02 (05) ◽  
pp. 567-575 ◽  
Author(s):  
Carlotta Marianecci ◽  
Luisa Di Marzio ◽  
Federica Rinaldi ◽  
Maria Carafa ◽  
Franco Alhaique
Keyword(s):  
Pulmonary Delivery ◽  
Innovative Approaches

Pulmonary Delivery of Liposome-Encapsulated Drugs in Asthma Therapy

1995 ◽  
Vol 4 (5) ◽  
pp. 331-337 ◽  
Author(s):  
Ricardo J. Gonzalez-Rothi ◽  
Hans Schreier
Keyword(s):  
Pulmonary Delivery ◽  
Asthma Therapy

Pulmonary delivery of chitosan-DNA nanoparticles enhances the immunogenicity of a DNA vaccine encoding HLA-A*0201-restricted T-cell epitopes of Mycobacterium tuberculosis

Vaccine ◽  
2004 ◽  
Vol 22 (13-14) ◽  
pp. 1609-1615 ◽  
Author(s):  
Maytal Bivas-Benita ◽  
Krista E. van Meijgaarden ◽  
Kees L.M.C. Franken ◽  
Hans E. Junginger ◽  
Gerrit Borchard ◽  
...  
Keyword(s):  
Mycobacterium Tuberculosis ◽  
T Cell ◽  
Dna Vaccine ◽  
Pulmonary Delivery ◽  
T Cell Epitopes ◽  
Dna Nanoparticles

scholarly journals Pulmonary delivery of docosahexaenoic acid mitigates bleomycin-induced pulmonary fibrosis

2014 ◽  
Vol 14 (1) ◽  
Author(s):  
Hongyun Zhao ◽  
Yee Chan-Li ◽  
Samuel L Collins ◽  
Yuan Zhang ◽  
Robert W Hallowell ◽  
...  
Keyword(s):  
Pulmonary Fibrosis ◽  
Docosahexaenoic Acid ◽  
Pulmonary Delivery

The nanoscale in pulmonary delivery. Part 1: deposition, fate, toxicology and effects

2007 ◽  
Vol 4 (6) ◽  
pp. 595-606 ◽  
Author(s):  
Philippe GA Rogueda ◽  
Daniela Traini
Keyword(s):  
Pulmonary Delivery

scholarly journals Biopharmaceutical Characterization of Nebulized Antimicrobial Agents in Rats: 5. Oseltamivir Carboxylate

2016 ◽  
Vol 60 (8) ◽  
pp. 5085-5087 ◽  
Author(s):  
Danilo Cesar Galindo Bedor ◽  
Sandrine Marchand ◽  
Isabelle Lamarche ◽  
Julian Laroche ◽  
Davi Pereira de Santana ◽  
...  
Keyword(s):  
Antimicrobial Agents ◽  
Area Under The Curve ◽  
Pulmonary Delivery ◽  
Epithelial Lining ◽  
Oseltamivir Carboxylate ◽  
Epithelial Lining Fluid

ABSTRACTThe aim of this study was to determine the biopharmaceutical characteristics of oseltamivir carboxylate (OC) after pulmonary delivery. After OC bolus and intratracheal nebulization (NEB) in rats, blood was collected and bronchoalveolar lavages (BALs) were performed. Epithelial lining fluid (ELF) concentrations were estimated from BAL fluid. The area under the curve (AUC) ratio for ELF to plasma was 842 times higher after NEB than after intravenous (i.v.) administration, indicating that OC nebulization offers a biopharmaceutical advantage over i.v. administration.

Biodegradable Solid Lipid Nanoparticle Flocculates for Pulmonary Delivery of Insulin

2012 ◽  
Vol 8 (5) ◽  
pp. 834-842 ◽  
Author(s):  
Xiaoyan Yang ◽  
Yongjun Liu ◽  
Chunxi Liu ◽  
Na Zhang
Keyword(s):  
Pulmonary Delivery ◽  
Solid Lipid Nanoparticle ◽  
Solid Lipid ◽  
Lipid Nanoparticle
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