Management of Locally Advanced and Recurrent Rectal Cancer

2015 ◽  
pp. 567-582
Author(s):  
Cherry E. Koh ◽  
Michael J. Solomon
Keyword(s):  
Rectal Cancer ◽  
Locally Advanced ◽  
Recurrent Rectal Cancer

scholarly journals 455 Proton Beam Therapy in Rectal Cancer: A Systematic Review and Meta-Analysis

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
M Fok ◽  
S Toh ◽  
J E Maducolil ◽  
H Fowler ◽  
R Clifford ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Proton Beam ◽  
Organs At Risk ◽  
Meta Analysis ◽  
Locally Advanced ◽  
Significant Risk ◽  
Proton Beam Therapy ◽  
Recurrent Rectal Cancer ◽  
Pelvic Bone ◽  
Dosimetric Data

Abstract Introduction Radiotherapy for locally advanced rectal cancer is conventionally performed using photon-based radiotherapy (PBR), carrying significant risk of toxicity to organs at risk (OAR). Proton beam therapy (PBT) potentially delivers equivalent dosimetric radiation to the targeted tissue with improved sparing of OAR. We aimed to compare dosimetric irradiation of OAR for PBT versus PBR in patients with rectal cancer and assess any oncological outcomes. Method An extensive electronic literature search was performed from inception till April 2020 and subsequent meta-analysis performed. Results Six articles met the inclusion criteria. Dosimetric data of irradiation delivered to OAR for PBT and PBR were calculated for the same patients. PBT had significantly less irradiated small bowel compared to 3DCRT and IMRT, (MD -16.95, 95% CI [-24.03, -9.88], p < 0.00001) and (MD -6.96, 95% CI [-12.99, -0.94], p = 0.02) respectively. Similar results were observed for bladder and pelvic bone marrow. Two studies reported clinical and oncological results for PBT in recurrent rectal cancer with overall survival reported as 43% and 68%. Conclusions Dosimetric treatment plans have less irradiation of OAR for rectal cancer with PBT compared to PBR. There is a need for further research in PBT and rectal cancer, as promising results have been shown in recurrent rectal cancer.

scholarly journals Double-barrelled wet colostomy formation after pelvic exenteration for locally advanced or recurrent rectal cancer

2016 ◽  
Vol 18 (11) ◽  
pp. O427-O431 ◽  
Author(s):  
A. L. A. Bloemendaal ◽  
R. Kraus ◽  
N. C. Buchs ◽  
F. C. Hamdy ◽  
R. Hompes ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Pelvic Exenteration ◽  
Locally Advanced ◽  
Recurrent Rectal Cancer

6078 POSTER Extended Surgery for Locally Advanced Primary and Recurrent Rectal Cancer – Experience of 30 Pelvic Exenterations

2011 ◽  
Vol 47 ◽  
pp. S414
Author(s):  
L.O. Petrov ◽  
V.l. Chissov ◽  
D.V. Sidorov ◽  
B.Y. Alekseev ◽  
A.V. Butenko ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Locally Advanced ◽  
Recurrent Rectal Cancer ◽  
Extended Surgery ◽  
Cancer Experience

scholarly journals Laparoscopic Total Pelvic Exenteration for Locally Advanced or Recurrent Rectal Cancer

2019 ◽  
Vol 72 (10) ◽  
pp. 559-566
Author(s):  
Kei Kimura ◽  
Masataka Ikeda ◽  
Jihyung Song ◽  
Michiko Hamanaka ◽  
Akihito Babaya ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Pelvic Exenteration ◽  
Locally Advanced ◽  
Recurrent Rectal Cancer ◽  
Total Pelvic Exenteration

scholarly journals Association of Image-Guided Navigation With Complete Resection Rate in Patients With Locally Advanced Primary and Recurrent Rectal Cancer

2020 ◽  
Vol 3 (7) ◽  
pp. e208522 ◽  
Author(s):  
Esther N. D. Kok ◽  
Ruben van Veen ◽  
Harald C. Groen ◽  
Wouter J. Heerink ◽  
Nikie J. Hoetjes ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Locally Advanced ◽  
Complete Resection ◽  
Recurrent Rectal Cancer ◽  
Resection Rate ◽  
Image Guided ◽  
Complete Resection Rate

Influence of the level of sacrectomy on survival in patients with locally advanced and recurrent rectal cancer

2019 ◽  
Vol 106 (4) ◽  
pp. 484-490 ◽  
Author(s):  
Y. C. Lau ◽  
K. Jongerius ◽  
C. Wakeman ◽  
A. G. Heriot ◽  
M. J. Solomon ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Locally Advanced ◽  
Recurrent Rectal Cancer

High Subcortical Sacral Resection {Hiss] for Locally Advanced & Recurrent Rectal Cancer Extending onto L5/S1/2

2020 ◽  
Vol 46 (2) ◽  
pp. e98
Author(s):  
Edward Pring ◽  
Laura Gould ◽  
Jordan Fletcher ◽  
Taylor Claire ◽  
Therese Hona ◽  
...  
Keyword(s):  
Rectal Cancer ◽  
Locally Advanced ◽  
Recurrent Rectal Cancer ◽  
Sacral Resection

A systematic review examining quality of life following pelvic exenteration for locally advanced and recurrent rectal cancer

2017 ◽  
Vol 19 (5) ◽  
pp. 430-436 ◽  
Author(s):  
E. Rausa ◽  
M. E. Kelly ◽  
L. Bonavina ◽  
P. R. O'Connell ◽  
D. C. Winter
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Rectal Cancer ◽  
Pelvic Exenteration ◽  
Locally Advanced ◽  
Recurrent Rectal Cancer
Sign in / Sign up

Export Citation Format

Share Document