Synthesis and Properties of Biodegradable Polymers Used as Synthetic Matrices for Tissue Engineering

Author(s):  
Wai Hung Wong ◽  
David J. Mooney
Author(s):  
Raffaele Conte ◽  
Francesco Riccitiello ◽  
Adriana De Luise ◽  
Orsolina Petillo ◽  
Carlo Rengo ◽  
...  

1995 ◽  
Vol 394 ◽  
Author(s):  
Jeffrey S. Hrkach ◽  
Jean Ou ◽  
Noah Lotan ◽  
Robert Langer

AbstractOne of the challenges in the field of tissue engineering is the development of optimal materials for use as scaffolds to support cell growth and tissue development. For this purpose, we are developing synthetic, biodegradable polymers with functional sites that provide the opportunity to covalently attach biologically active molecules to the polymers, so they can predictably interact with cells in a favorable manner to enhance cell attachment and growth. The preparation of poly(L-lactic acid-co-aspartic acid) comb-like graft copolymers from poly(L-lactic acid-co-β-benzyl-L-aspartate), and the casting of polymer films by solvent evaporation were carried out.


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