Deep Brain Stimulation for Chronic Pain: Long-Term Results and Complications

1988 ◽  
pp. 395-407 ◽  
Author(s):  
Robert M. Levy ◽  
Sharon Lamb ◽  
John E. Adams
Keyword(s):  
Chronic Pain ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Long Term Results ◽  
Deep Brain

scholarly journals Deep brain stimulation for the treatment of various chronic pain syndromes

2006 ◽  
Vol 21 (6) ◽  
pp. 1-8 ◽  
Author(s):  
Dirk Rasche ◽  
Patricia C. Rinaldi ◽  
Ronald F. Young ◽  
Volker M. Tronnier
Keyword(s):  
Spinal Cord ◽  
Chronic Pain ◽  
Neuropathic Pain ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Long Term Results ◽  
Pain Syndromes ◽  
Chronic Pain Syndromes ◽  
Deep Brain

Object Electrical intracerebral stimulation (also referred to as deep brain stimulation [DBS]) is a tool for the treatment of chronic pain states that do not respond to less invasive or conservative treatment options. Careful patient selection, accurate target localization, and identification with intraoperative neurophysiological techniques and blinded test evaluation are the key requirements for success and good long-term results. The authors present their experience with DBS for the treatment of various chronic pain syndromes. Methods In this study 56 patients with different forms of neuropathic and mixed nociceptive/neuropathic pain syndromes were treated with DBS according to a rigorous protocol. The postoperative follow-up duration ranged from 1 to 8 years, with a mean of 3.5 years. Electrodes were implanted in the somatosensory thalamus and the periventricular gray region. Before implantation of the stimulation device, a double-blinded evaluation was carefully performed to test the effect of each electrode on its own as well as combined stimulation with different parameter settings. The best long-term results were attained in patients with chronic low-back and leg pain, for example, in so-called failed–back surgery syndrome. Patients with neuropathic pain of peripheral origin (such as complex regional pain syndrome Type II) also responded well to DBS. Disappointing results were documented in patients with central pain syndromes, such as pain due to spinal cord injury and poststroke pain. Possible reasons for the therapeutic failures are discussed; these include central reorganization and neuroplastic changes of the pain-transmitting pathways and pain modulation centers after brain and spinal cord lesions. Conclusions The authors found that, in carefully selected patients with chronic pain syndromes, DBS can be helpful and can add to the quality of life.

Long-term Results of Deep Brain Stimulation of the Subcallosal Cingulate for Medication-Resistant Bipolar I Depression and Rapid Cycling Bipolar II Depression

2017 ◽  
Vol 81 (4) ◽  
pp. e33-e34 ◽  
Author(s):  
Cristina V. Torres ◽  
Elena Ezquiaga ◽  
Marta Navas ◽  
Maria Angeles García Pallero ◽  
Rafael G Sola
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Long Term Results ◽  
Rapid Cycling ◽  
Bipolar Ii ◽  
Deep Brain ◽  
Stimulation Of

Long-term results of deep brain stimulation in a cohort of eight children with isolated dystonia

2016 ◽  
Vol 263 (11) ◽  
pp. 2319-2326 ◽  
Author(s):  
P. Krause ◽  
K. Lauritsch ◽  
A. Lipp ◽  
A. Horn ◽  
B. Weschke ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Long Term Results ◽  
Deep Brain

scholarly journals MEG Can Map Short and Long-Term Changes in Brain Activity following Deep Brain Stimulation for Chronic Pain

PLoS ONE ◽  
2012 ◽  
Vol 7 (6) ◽  
pp. e37993 ◽  
Author(s):  
Hamid R. Mohseni ◽  
Penny P. Smith ◽  
Christine E. Parsons ◽  
Katherine S. Young ◽  
Jonathan A. Hyam ◽  
...  
Keyword(s):  
Chronic Pain ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Brain Activity ◽  
Long Term Changes ◽  
Short And Long Term ◽  
Deep Brain

scholarly journals Nucleus Accumbens Deep Brain Stimulation for Alcohol Addiction – Safety and Clinical Long-term Results of a Pilot Trial

2016 ◽  
Vol 49 (04) ◽  
pp. 170-173 ◽  
Author(s):  
U. Müller ◽  
V. Sturm ◽  
J. Voges ◽  
H.-J. Heinze ◽  
I. Galazky ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Nucleus Accumbens ◽  
Brain Stimulation ◽  
Pilot Trial ◽  
Alcohol Addiction ◽  
Long Term Results ◽  
Deep Brain

Long-term follow-up of deep brain stimulation for Meige syndrome

2010 ◽  
Vol 29 (2) ◽  
pp. E5 ◽  
Author(s):  
Mark K. Lyons ◽  
Barry D. Birch ◽  
Renee A. Hillman ◽  
Orland K. Boucher ◽  
Virgilio Gerald H. Evidente
Keyword(s):  
Deep Brain Stimulation ◽  
Parkinson Disease ◽  
Brain Stimulation ◽  
Long Term Results ◽  
Meige Syndrome ◽  
Pallidal Stimulation ◽  
Long Term Follow Up ◽  
Deep Brain

Object Meige syndrome is characterized by blepharospasm, cervical dystonia, and facial oromandibular dystonia. The medical treatment of this condition is largely unsuccessful over time and is a major source of decreased quality of life in those patients suffering from this disease. Recent advances in the application of deep brain stimulation (DBS) surgery techniques for many disorders have prompted several recent reports of DBS for medically refractory cases of Meige syndrome. While the etiology for this disorder is unknown, it is considered by many investigators to be a form of idiopathic torsion dystonia. Pallidal stimulation is widely considered to be effective for dystonia. Methods The authors report the long-term results of bilateral globus pallidus internus (GPi) or subthalamic nucleus (STN) stimulation in 3 patients with Meige syndrome and 1 patient with Parkinson disease and associated craniofacial dystonia treated at their center. Results Initial 12-month and long-term follow-up Burke-Fahn-Marsden scores were substantially improved in all 4 patients compared with preoperative scores. Conclusions Bilateral GPi DBS may be an effective and safe treatment for medically refractory Meige syndrome. The results are comparable with those reported in the literature. Sustained and long-term improvement in symptoms does appear to be reproducible across reports. The authors' patient with Parkinson disease and associated craniofacial dystonia syndrome undergoing bilateral STN DBS noted immediate and sustained improvement in his symptoms. Further study is required, but these results, along with the other reports, suggest that bilateral GPi DBS is an effective treatment for medically refractory Meige syndrome.

Long-Term Results of Deep Brain Stimulation of the Mamillotegmental Fasciculus in Chronic Cluster Headache

2018 ◽  
Vol 96 (4) ◽  
pp. 215-222 ◽  
Author(s):  
Fernando Seijo-Fernandez ◽  
Antonio Saiz ◽  
Elena Santamarta ◽  
Lydia Nader ◽  
Marco Antonio Alvarez-Vega ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Cluster Headache ◽  
Brain Stimulation ◽  
Chronic Cluster Headache ◽  
Long Term Results ◽  
Deep Brain ◽  
Stimulation Of

scholarly journals A DECADE OF EXPERIENCE WITH DEEP BRAIN STIMULATION FOR PATIENTS WITH REFRACTORY MEDIAL TEMPORAL LOBE EPILEPSY

2012 ◽  
Vol 23 (01) ◽  
pp. 1250034 ◽  
Author(s):  
KRISTL VONCK ◽  
MATHIEU SPRENGERS ◽  
EVELIEN CARRETTE ◽  
INE DAUWE ◽  
MARIJKE MIATTON ◽  
...  
Keyword(s):  
Deep Brain Stimulation ◽  
Temporal Lobe ◽  
Seizure Frequency ◽  
Brain Stimulation ◽  
Medial Temporal Lobe ◽  
Neuropsychological Functioning ◽  
Long Term Results ◽  
Deep Brain

In this study, we present long-term results from patients with medial temporal lobe (MTL) epilepsy treated with deep brain stimulation (DBS). Since 2001, 11 patients (8M) with refractory MTL epilepsy underwent MTL DBS. When unilateral DBS failed to decrease seizures by > 90%, a switch to bilateral MTL DBS was proposed. After a mean follow-up of 8.5 years (range: 67–120 months), 6/11 patients had a ≥ 90% seizure frequency reduction with 3/6 seizure-free for > 3 years; three patients had a 40%–70% reduction and two had a < 30% reduction. In 3/5 patients switching to bilateral DBS further improved outcome. Uni- or bilateral MTL DBS did not affect neuropsychological functioning. This open study with an extended long-term follow-up demonstrates maintained efficacy of DBS for MTL epilepsy. In more than half of the patients, a seizure frequency reduction of at least 90% was reached. Bilateral MTL DBS may herald superior efficacy in unilateral MTL epilepsy.

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