Palliatives to Underproduction of Nitric Oxide as Assayed by EPR Spectroscopy

1997 ◽  
pp. 271-291 ◽  
Author(s):  
Claire Ducrocq ◽  
Annie Guissani
Keyword(s):  
Nitric Oxide ◽  
Epr Spectroscopy

Increased synthesis of nitric oxide in rat brain cortex due to halogenated volatile anesthetics confirmed by EPR spectroscopy

2002 ◽  
Vol 46 (4) ◽  
pp. 378-383 ◽  
Author(s):  
L. Baumane ◽  
M. Dzintare ◽  
L. Zvejniece ◽  
D. Meirena ◽  
L. Lauberte ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Rat Brain ◽  
Epr Spectroscopy ◽  
Brain Cortex ◽  
Volatile Anesthetics ◽  
Rat Brain Cortex

Sensitive quantitation of nitric oxide by EPR spectroscopy

1996 ◽  
Vol 21 (5) ◽  
pp. 733-737 ◽  
Author(s):  
Koichiro Tsuchiya ◽  
Masumitsu Takasugi ◽  
Kazuo Minakuchi ◽  
Kenji Fukuzawa
Keyword(s):  
Nitric Oxide ◽  
Epr Spectroscopy

In vivo three-dimensional EPR imaging of nitric oxide production from isosorbide dinitrate in mice

1998 ◽  
Vol 274 (5) ◽  
pp. G857-G862 ◽  
Author(s):  
Satoshi Fujii ◽  
Yasuhiro Suzuki ◽  
Tetsuhiko Yoshimura ◽  
Hitoshi Kamada
Keyword(s):  
Nitric Oxide ◽  
Isosorbide Dinitrate ◽  
Epr Spectroscopy ◽  
Ex Vivo ◽  
Three Dimensional ◽  
Water Soluble ◽  
Whole Body ◽  
No Production ◽  
Epr Signal

Recently, in vivo electron paramagnetic resonance (EPR) spectroscopy and imaging have been widely used to investigate free radical distribution and metabolism in tissues, organs, and whole body of small animals. Endogenous nitric oxide (NO) is an attractive target of this method. In the present study, NO production from a nitrovasodilator, isosorbide dinitrate (ISDN), in live mice was investigated by in vivo EPR spectroscopy and imaging combined with the spin-trapping technique. A highly water-soluble Fe complex with N-(dithiocarboxy)sarcosine (DTCS) was used as an NO-trapping agent. Mice received [14N]ISDN, and the Fe-DTCS complex subcutaneously exhibited the characteristic triplet EPR signal of the NO adduct [14NO-Fe(DTCS)2]2−. Using [15N]ISDN instead of [14N]ISDN, we were able to observe that the doublet EPR signal stemmed from the15NO adduct, which directly demonstrated that NO was produced from ISDN. The three-dimensional EPR images of the upper abdomen of living mice showed that the NO adducts were distributed in the liver and the kidneys. This EPR image combined with the ex vivo EPR measurements of the blood suggested that NO production from ISDN occurred in the liver in this experimental condition.

Nitric oxide Versus Reactive Oxygen Species Measurements in Blood using EPR Spectroscopy for Assessment of Endothelial Dysfunction

2013 ◽  
Vol 65 ◽  
pp. S103-S104
Author(s):  
Bartosz Proniewski ◽  
Antonina Chmura-Skirliñska ◽  
Agnieszka Broniec ◽  
Ryszard J Gurbiel ◽  
Wojciech Froncisz
Keyword(s):  
Nitric Oxide ◽  
Reactive Oxygen Species ◽  
Endothelial Dysfunction ◽  
Epr Spectroscopy ◽  
Reactive Oxygen ◽  
Oxygen Species

Reaction of Substituted Anthracenes and a Butadiene with Nitric Oxide: Product Formation Determined by EPR Spectroscopy

1997 ◽  
Vol 27 (4) ◽  
pp. 377-388 ◽  
Author(s):  
Dietmar Pfeiler ◽  
I. Darren Grice ◽  
Steven E. Bottle ◽  
Graeme R. Hanson
Keyword(s):  
Nitric Oxide ◽  
Epr Spectroscopy ◽  
Product Formation ◽  
Oxide Product

In Vivo/In Situ Detection of Nitric Oxide Using Low-Frequency EPR Spectroscopy

2003 ◽  
pp. 227-238
Author(s):  
Pei Tsai ◽  
Supatra Porasuphatana ◽  
Howard J. Halpern ◽  
Eugene D. Barth ◽  
Gerald M. Rosen
Keyword(s):  
Nitric Oxide ◽  
Epr Spectroscopy ◽  
Low Frequency ◽  
In Situ Detection
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