Lipids and Proteins of Lipoproteins in Human Atherosclerosis

Author(s):  
P. Avogaro ◽  
G. Bittolo-Bon ◽  
G. Cazzolato ◽  
F. Belussi ◽  
E. Pontoglio
Author(s):  
K. Florian Klemp ◽  
J.R. Guyton

The earliest distinctive lesions in human atherosclerosis are fatty streaks (FS), characterized initially by lipid-laden foam cell formation. Fibrous plaques (FP), the clinically significant lesions, differ from FS in several respects. In addition to foam cells, the FP also exhibit fibromuscular proliferation and a necrotic core region rich in extracellular lipid. The possible transition of FS into mature FP has long been debated, however. A subset of FS described by Katz etal., was intermediate in lipid composition between ordinary FS and FP. We investigated this hypothesis by electron microscopic cytochemistry by employing a tissue processing technique previously described by our laboratory. Osmium-tannic acid-paraphenylenediamine (OTAP) tissue preparation enabled ultrastructural analysis of lipid deposits to discern features characteristic of mature fibrous plaques.


Circulation ◽  
1998 ◽  
Vol 97 (25) ◽  
pp. 2494-2498 ◽  
Author(s):  
Barry S. Oemar ◽  
Marcel R. Tschudi ◽  
Nelson Godoy ◽  
Victor Brovkovich ◽  
Tadeusz Malinski ◽  
...  

Science ◽  
1954 ◽  
Vol 120 (3105) ◽  
pp. 31-32 ◽  
Author(s):  
A. Cairns ◽  
P. Constantinides

Author(s):  
Han Jin ◽  
Barend Mees ◽  
Erik AL Biessen ◽  
Judith C Sluimer

1997 ◽  
Vol 134 (1-2) ◽  
pp. 262
Author(s):  
N. Kipshidze ◽  
N. Kakauridze ◽  
D. Shalamberidze

Author(s):  
Mark L. Armstrong ◽  
Marjorie B. Megan ◽  
Donald D. Heistad

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