Mechanisms of Action of Adenosine on Vascular Smooth Muscle and Cardiac Cells

1983 ◽  
pp. 319-332 ◽  
Author(s):  
Rafael Rubio ◽  
Maureen T. Knabb ◽  
Tokumasa Tsukada ◽  
Robert M. Berne
Keyword(s):  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Mechanisms Of Action ◽  
Cardiac Cells

scholarly journals Sequential activation of alpha-actin genes during avian cardiogenesis: vascular smooth muscle alpha-actin gene transcripts mark the onset of cardiomyocyte differentiation.

1988 ◽  
Vol 107 (6) ◽  
pp. 2575-2586 ◽  
Author(s):  
D L Ruzicka ◽  
R J Schwartz
Keyword(s):  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Cardiac Cells ◽  
Actin Gene ◽  
Heart Tube ◽  
Specific Expression ◽  
Actin Genes ◽  
Beta Actin ◽  
Smooth Muscle Alpha Actin ◽  
Alpha Actin

The expression of cytoplasmic beta-actin and cardiac, skeletal, and smooth muscle alpha-actins during early avian cardiogenesis was analyzed by in situ hybridization with mRNA-specific single-stranded DNA probes. The cytoplasmic beta-actin gene was ubiquitously expressed in the early chicken embryo. In contrast, the alpha-actin genes were sequentially activated in avian cardiac tissue during the early stages of heart tube formation. The accumulation of large quantities of smooth muscle alpha-actin transcripts in epimyocardial cells preceded the expression of the sarcomeric alpha-actin genes. The accumulation of skeletal alpha-actin mRNAs in the developing heart lagged behind that of cardiac alpha-actin by several embryonic stages. At Hamburger-Hamilton stage 12, the smooth muscle alpha-actin gene was selectively down-regulated in the heart such that only the conus, which subsequently participates in the formation of the vascular trunks, continued to express this gene. This modulation in smooth muscle alpha-actin gene expression correlated with the beginning of coexpression of sarcomeric alpha-actin transcripts in the epimyocardium and the onset of circulation in the embryo. The specific expression of the vascular smooth muscle alpha-actin gene marks the onset of differentiation of cardiac cells and represents the first demonstration of coexpression of both smooth muscle and striated alpha-actin genes within myogenic cells.

scholarly journals Effect of hydrogen sulfide on the contractile activity of smooth muscle cells from the rat aorta

2010 ◽  
Vol 9 (6) ◽  
pp. 12-17
Author(s):  
M. B. Baskakov ◽  
S. V. Gusakova ◽  
A. S. Zheludeva ◽  
L. V. Smagly ◽  
I. V. Kovalyov ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Hydrogen Sulfide ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Contractile Activity ◽  
Muscle Cells ◽  
Rat Aorta ◽  
Mechanisms Of Action ◽  
High K ◽  
Lower Amplitude

In preparations of rat aorta, used as a model of muscular type arteries, the method mehanografii studied the effect of hydrogen sulfide on the reduction of isolated of vascular smooth muscle. Found that hydrogen sulfide in concentrations 1—50 mmol increases the mechanical stress of smooth muscle in high-K + medium. At higher concentrations (300—1 000 mmol) H2S leads to lower amplitude giperkalievoy contraction in high-K + medium. Reduction of smooth muscle cells caused by phenylephrine inhibited the action of hydrogen sulfide in the whole range of concentrations. The causes of differences in data obtained with the results of studies in other laboratories, and possible mechanisms of action of hydrogen sulfide on the contractile activity of vascular smooth muscle.

Cellular Mechanisms of Action of a Ouabain-Like Factor in Vascular Smooth-Muscle Cells

1993 ◽  
Vol 22 (Supplement 2) ◽  
pp. S16-S19 ◽  
Author(s):  
Harald Meyer-Lehnert ◽  
Christine Wanning ◽  
Harald Michel ◽  
Angela Bäcker ◽  
Herbert J. Kramer
Keyword(s):  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Vascular Smooth Muscle Cells ◽  
Muscle Cells ◽  
Mechanisms Of Action ◽  
Cellular Mechanisms

Upregulation and Mechanisms of Action of the Nitric Oxide Dioxygenase Cytoglobin in Vascular Smooth Muscle in Restenosis after Carotid Injury

2010 ◽  
Vol 49 ◽  
pp. S23
Author(s):  
Katherine E. Halligan ◽  
Frances L. Jourd'heuil ◽  
Wael F. Alzawahra ◽  
Margarida Barroso ◽  
Harold A Singer ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Mechanisms Of Action ◽  
Carotid Injury

scholarly journals Calcimimetics increase CaSR expression and reduce mineralization in vascular smooth muscle cells: mechanisms of action

2013 ◽  
Vol 101 (2) ◽  
pp. 256-265 ◽  
Author(s):  
Lucie Hénaut ◽  
Cédric Boudot ◽  
Ziad A. Massy ◽  
Irene Lopez-Fernandez ◽  
Sebastien Dupont ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Vascular Smooth Muscle ◽  
Smooth Muscle Cells ◽  
Vascular Smooth Muscle Cells ◽  
Muscle Cells ◽  
Mechanisms Of Action
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