Operations for Infected Abdominal Wound Dehiscence and Necrotizing Soft Tissue Infection of the Abdominal Wall

2011 ◽  
pp. 504-507
Author(s):  
Kristen C. Sihler
Keyword(s):  
Soft Tissue ◽  
Abdominal Wall ◽  
Soft Tissue Infection ◽  
Wound Dehiscence ◽  
Tissue Infection ◽  
Abdominal Wound ◽  
Necrotizing Soft Tissue Infection ◽  
Abdominal Wound Dehiscence

scholarly journals An unwonted case of Meleney’s like abdominal wall necrotizing soft tissue infection

2019 ◽  
Vol 6 (12) ◽  
pp. 4566
Author(s):  
Gorrepati Rohith ◽  
Thirugnanasambandam Nelson ◽  
Pannerselvam Vinodhini ◽  
Ashok Kumar Sahoo
Keyword(s):  
Soft Tissue ◽  
Abdominal Wall ◽  
Soft Tissue Infection ◽  
Road Traffic ◽  
Penetrating Injury ◽  
Tissue Infection ◽  
Tissue Loss ◽  
Microbial Infection ◽  
Necrotizing Soft Tissue Infection ◽  
Mortality And Morbidity

Poly-microbial infection leading to necrotizing soft tissue infection is known to cause fulminant sepsis resulting in significant mortality and morbidity despite aggressive medical and surgical management. We present a case of Meleney’s like synergistic gangrene of abdominal wall culminating in full blown sepsis and death in the background of penetrating injury to the abdomen. Our patient was a 36 year old female, who presented with a penetrating injury to the abdomen due to a road traffic accident resulting in a laceration over the anterior abdominal wall with evisceration of bowel and omentum. After initial resuscitation, patient was immediately taken up for exploration and multiple small bowel perforations were primarily repaired. Postoperatively, she developed severe polymicrobial infection at the laceration site which extended all over the abdomen. She was treated with broad spectrum antibiotics based on culture and sensitivity and serial debridement of necrosis was done. She developed ventral hernia during the course, which was complicated by necrosis of bowel which was managed by resection and anastomosis. Postoperatively, she developed multi-organ dysfunction due to sepsis and succumbed to infection. We imply on the necessity of innovative techniques and multidisciplinary approach for controlling sepsis and compensating the significant soft tissue loss due to widespread necrotizing infection. 

scholarly journals Necrotizing soft tissue infection on the abdominal wall. How to proceed?

2020 ◽  
Vol 86 (6) ◽  
Author(s):  
Raquel M. Fresnedo-Pérez ◽  
Ana Cabrera-Pereira ◽  
Rubén Rodríguez-García ◽  
Desirée Díaz-González ◽  
Javier Albaladejo-Magdalena
Keyword(s):  
Soft Tissue ◽  
Abdominal Wall ◽  
Soft Tissue Infection ◽  
Tissue Infection ◽  
Necrotizing Soft Tissue Infection

Group G Streptococcal Necrotizing Soft Tissue Infection

2016 ◽  
Vol 78 (6) ◽  
pp. 644-649
Author(s):  
Eriko MAEHARA ◽  
Gaku TSUJI ◽  
Yukihiro MIZOTE ◽  
Naohide TAKEUCHI ◽  
Masutaka FURUE
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Infection ◽  
Tissue Infection ◽  
Necrotizing Soft Tissue Infection

Can Paronychia Cause a Remote Necrotizing Soft Tissue Infection?

2011 ◽  
Vol 40 (1) ◽  
pp. e11-e13 ◽  
Author(s):  
Julian E. Losanoff ◽  
Anne E. Missavage ◽  
Paul Linneman ◽  
Boyd E. Terry
Keyword(s):  
Soft Tissue ◽  
Soft Tissue Infection ◽  
Tissue Infection ◽  
Necrotizing Soft Tissue Infection

scholarly journals Hyperbaric oxygen treatment impacts oxidative stress markers in patients with necrotizing soft-tissue infection

2021 ◽  
pp. jim-2021-001837
Author(s):  
Morten Hedetoft ◽  
Peter Østrup Jensen ◽  
Claus Moser ◽  
Julie Vinkel ◽  
Ole Hyldegaard
Keyword(s):  
Oxidative Stress ◽  
Septic Shock ◽  
Soft Tissue ◽  
Hyperbaric Oxygen ◽  
Soft Tissue Infection ◽  
Tissue Infection ◽  
Heme Oxygenase 1 ◽  
Necrotizing Soft Tissue Infection ◽  
Before And After ◽  
Nitrite Nitrate

Necrotizing soft-tissue infection (NSTI) is a rare, severe, and fast-progressing bacterial infection associated with a high risk of developing sepsis or septic shock. Increasing evidence indicates that oxidative stress is crucial in the development and progression of sepsis, but its role in NSTI specifically has not been investigated. Some patients with NSTI receive hyperbaric oxygen (HBO2) treatment as the restoration of oxidative stress balance is considered an important mechanism of action, which HBO2 facilitates. However, a gap in knowledge exists regarding the effect of HBO2 treatment on oxidative stress in patients with NSTI. In the present observational study, we aimed to investigate HBO2 treatment effects on known markers of oxidative stress in patients with NSTI. We measured plasma myeloperoxidase (MPO), superoxide dismutase (SOD), heme oxygenase-1 (HO-1) and nitrite+nitrate in 80 patients with NSTI immediately before and after their first HBO2 treatment, and on the following day. We found that HBO2 treatment was associated with a significant increase in MPO and SOD by a median of 3.4 and 8.8 ng/mL, respectively. Moreover, we observed an HBO2 treatment-associated increase in HO-1 in patients presenting with septic shock (n=39) by a median of 301.3 pg/mL. All markers were significantly higher in patients presenting with septic shock compared to patients without shock, and all markers correlated with disease severity. High baseline SOD was associated with 90-day mortality. In conclusion, HBO2 treatment was associated with an increase in MPO and SOD in patients with NSTI, and oxidative stress was more pronounced in patients with septic shock.

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