Biodegradable Polymers in Drug Delivery Systems

2011 ◽  
pp. 107-123 ◽  
Author(s):  
Jamie Tsung ◽  
Diane J. Burgess
Keyword(s):  
Drug Delivery ◽  
Biodegradable Polymers ◽  
Drug Delivery Systems ◽  
Delivery Systems

FROM PLASTICS TO ADVANCED POLYMER IMPLANTS: THE ESSENTIALS OF POLYMER CHEMISTRY

COSMOS ◽  
2008 ◽  
Vol 04 (01) ◽  
pp. 1-15 ◽  
Author(s):  
JOACHIM SAY CHYE LOO
Keyword(s):  
Drug Delivery ◽  
Tissue Engineering ◽  
Biodegradable Polymers ◽  
Human Body ◽  
Water Purification ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Polymer Chemistry ◽  
Biomedical Implants ◽  
Polymer Implants

Man has been using plastics for thousands of years, and some of the earlier uses of plastics include spoons, buttons and combs. Today, plastics are used for a myriad of applications, such as for aerospace, microelectronics and water purification. With polymer chemistry, man has been able to alter the properties of plastics or polymers to suit almost any application. Their properties can also be tailored for use as advanced biomedical implants in the human body. An example of such a polymer is the biocompatible lactide/glycolide polyesters. These biodegradable polymers are currently used as sutures, drug delivery systems, temporary implants and even as scaffolds for tissue engineering.

New biodegradable polymers for injectable drug delivery systems

1999 ◽  
Vol 62 (1-2) ◽  
pp. 109-114 ◽  
Author(s):  
B. Jeong ◽  
Y.K. Choi ◽  
Y.H. Bae ◽  
G. Zentner ◽  
S.W. Kim
Keyword(s):  
Drug Delivery ◽  
Biodegradable Polymers ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Injectable Drug

scholarly journals PLGA – THE SMART POLYMER FOR DRUG DELIVERY

2021 ◽  
Vol 9 (5) ◽  
pp. 334-345
Author(s):  
N. Surya ◽  
S. Bhattacharyya
Keyword(s):  
Drug Delivery ◽  
Biodegradable Polymers ◽  
Biomedical Applications ◽  
Drug Delivery Systems ◽  
Glycolic Acid ◽  
Delivery Systems ◽  
Nano Particles ◽  
Natural Polymers ◽  
Smart Polymer ◽  
Novel Drug

Polymers have become an integral part of novel drug delivery system. One such successful biodegradable polymer is poly lactic-co-glycolic acid (PLGA) which consists of polyesters of lactic acid and glycolic acid. It is one of the FDA-approved biodegradable polymers which is extensively used for therapeutic purposes in recent times.The aim. To illuminate researchers on the chemistry, novel properties and applications of PLGA in pharmaceutical fields.Materials and methods. Various internet sources like Science Direct, Scopus, Web of Science, PubMed and google scholar were used as the data source. The key words search was carried out for the following words and combinations: PLGA, Novel drug delivery, PLGA Nano particles, biomedical applications of PLGA.Results. Pharmaceutical and biomedical industries are flooded with the use of synthetic and natural polymers. The mechanical and viscoelastic properties of the polymers make them suitable for the temporal and spatial delivery of therapeutic agents for an extended period. Employment of copolymerization techniques lead to the modification of water solubility of the polymers and make them suitable for various applications of drug delivery systems. Biodegradable polymers due to their biocompatibility and biodegradable property have attracted their use in novel drug delivery systems. PLGA is one of them. PLGA is versatile as it can be fabricated into any size, shape, and can be used to encapsulate small molecules, tissue engineering, and bone repair, etc.Conclusion. The sensitivity and biodegradability of PLGA makes it a smart polymer for targeted and sustained delivery of drugs and in various biomedical applications.

Surface Chemistry of Biodegradable Polymers for Drug Delivery Systems

ChemInform ◽  
2006 ◽  
Vol 37 (7) ◽  
Author(s):  
Chang-Sik Ha ◽  
Joseph A. Jr. Gardella
Keyword(s):  
Drug Delivery ◽  
Surface Chemistry ◽  
Biodegradable Polymers ◽  
Drug Delivery Systems ◽  
Delivery Systems

scholarly journals Synthetic biodegradable polymers as drug delivery systems for bone morphogenetic proteins

2005 ◽  
Vol 57 (7) ◽  
pp. 1037-1048 ◽  
Author(s):  
N SAITO ◽  
N MURAKAMI ◽  
J TAKAHASHI ◽  
H HORIUCHI ◽  
H OTA ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Biodegradable Polymers ◽  
Bone Morphogenetic Proteins ◽  
Drug Delivery Systems ◽  
Delivery Systems

New biodegradable polymers of L-lactic acid and aromatic hydroxy acids and their applications in drug delivery systems

1992 ◽  
Vol 81 (1) ◽  
pp. 31-38 ◽  
Author(s):  
Kazumichi Imasaka ◽  
Masaru Yoshida ◽  
Hironobu Fukuzaki ◽  
Masaharu Asano ◽  
Minoru Kumakura ◽  
...  
Keyword(s):  
Drug Delivery ◽  
Lactic Acid ◽  
Biodegradable Polymers ◽  
Drug Delivery Systems ◽  
Delivery Systems ◽  
Hydroxy Acids
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