Mortality in Intensive Care and the Role of Enteral Nutrition in Trauma Patients

Author(s):  
Gordon S. Doig ◽  
Fiona Simpson ◽  
Philippa T. Heighes
2015 ◽  
pp. 1333-1338
Author(s):  
Gordon S. Doig ◽  
Fiona Simpson ◽  
Philippa T. Heighes

2006 ◽  
Vol 15 (4) ◽  
pp. 402-412 ◽  
Author(s):  
Anthony Limpus ◽  
Wendy Chaboyer ◽  
Ellen McDonald ◽  
Lukman Thalib

• Objective To systematically review the randomized trials, observational studies, and survey evidence on compression and pneumatic devices for thromboprophylaxis in intensive care patients. • Methods Published studies on the use of compression and pneumatic devices in intensive care patients were assessed. A meta-analysis was conducted by using the randomized controlled trials. • Results A total of 21 relevant studies (5 randomized controlled trials, 13 observational studies, and 3 surveys) were found. A total of 811 patients were randomized in the 5 randomized controlled trials; 3421 patients participated in the observational studies. Trauma patients only were enrolled in 4 randomized controlled trials and 4 observational studies. Meta-analysis of 2 randomized controlled trials with similar populations and outcomes revealed that use of compression and pneumatic devices did not reduce the incidence of venous thromboembolism. The pooled risk ratio was 2.37, indicative of favoring the control over the intervention in reducing the deep venous thrombosis; however, the 95% CI of 0.57 to 9.90 indicated no significant differences between the intervention and the control. A range of methodological issues, including bias and confounding variables, make meaningful interpretation of the observational studies difficult. • Conclusions The limited evidence suggests that use of compressive and pneumatic devices yields results not significantly different from results obtained with no treatment or use of low-molecular-weight heparin. Until large randomized controlled trials are conducted, the role of mechanical approaches to thromboprophylaxis for intensive care patients remains uncertain.


2020 ◽  
Vol 23 (3) ◽  
pp. 163-167
Author(s):  
Peng-Fei Li ◽  
Yao-Li Wang ◽  
Yu-Li Fang ◽  
Ling Nan ◽  
Jian Zhou ◽  
...  

2012 ◽  
Vol 36 (6) ◽  
pp. 721-731 ◽  
Author(s):  
Ryan T. Hurt ◽  
Thomas H. Frazier ◽  
Stephen A. McClave ◽  
Neil E. Crittenden ◽  
Christopher Kulisek ◽  
...  

2005 ◽  
Vol 22 (Supplement 34) ◽  
pp. 175-176
Author(s):  
D. Boura ◽  
A. Kakavouli ◽  
P. Botsis ◽  
M. Stavropoulou ◽  
E. Ioannidou

2015 ◽  
Vol 24 (2) ◽  
pp. e1-e5 ◽  
Author(s):  
Victoria Bengualid ◽  
Goutham Talari ◽  
David Rubin ◽  
Aiham Albaeni ◽  
Ronald L. Ciubotaru ◽  
...  

Background The role of fever in trauma patients remains unclear. Fever occurs as a response to release of cytokines and prostaglandins by white blood cells. Many factors, including trauma, can trigger release of these factors. Objectives To determine whether (1) fever in the first 48 hours is related to a favorable outcome in trauma patients and (2) fever is more common in patients with head trauma. Method Retrospective study of trauma patients admitted to the intensive care unit for at least 2 days. Data were analyzed by using multivariate analysis. Results Of 162 patients studied, 40% had fever during the first 48 hours. Febrile patients had higher mortality rates than did afebrile patients. When adjusted for severity of injuries, fever did not correlate with mortality. Neither the incidence of fever in the first 48 hours after admission to the intensive care unit nor the number of days febrile in the unit differed between patients with and patients without head trauma (traumatic brain injury). About 70% of febrile patients did not have a source found for their fever. Febrile patients without an identified source of infection had lower peak white blood cell counts, lower maximum body temperature, and higher minimum platelet counts than did febrile patients who had an infectious source identified. The most common infection was pneumonia. Conclusions No relationship was found between the presence of fever during the first 48 hours and mortality. Patients with traumatic brain injury did not have a higher incidence of fever than did patients without traumatic brain injury. About 30% of febrile patients had an identifiable source of infection. Further studies are needed to understand the origin and role of fever in trauma patients. (American Journal of Critical Care. 2015; 24:e1–e5)


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