The AH Receptor

2003 ◽  
pp. 149-182 ◽  
Author(s):  
Guang Yao ◽  
Eric B. Harstad ◽  
Christopher A. Bradfield
Keyword(s):  
Ah Receptor

scholarly journals THE Ah PHENOTYPE. SURVEY OF FORTY-EIGHT RAT STRAINS AND TWENTY INBRED MOUSE STRAINS

Genetics ◽  
1982 ◽  
Vol 100 (1) ◽  
pp. 79-87
Author(s):  
Daniel W Nebert ◽  
Nancy M Jensen ◽  
Hisashi Shinozuka ◽  
Heinz W Kunz ◽  
Thomas J Gill
Keyword(s):  
Specific Activity ◽  
Inbred Mouse ◽  
Inbred Mouse Strain ◽  
Mouse Strains ◽  
Ah Receptor ◽  
Inbred Mouse Strains ◽  
Sprague Dawley ◽  
Rat Strains ◽  
Specific Activities ◽  
Inbred Rat

ABSTRACT Forty-four inbred and four randombred rat strains and 20 inbred mouse strains were examined for their Ah phenotype by determining the induction of liver microsomal aryl hydrocarbon (benzo[a]pyrene) hydroxylase activity (EC 1.14.14.1) by intraperitoneal treatment with either β-naphthoflavone or 3-methylcholanthrene. All 48 rat strains were found to be Ah-responsive. The maximally induced hydroxylase specific activities of the ALB/Pit, MNR/Pit, MR/Pit, SHR/Pit, and Sprague-Dawley strains were of the same order of magnitude as the basal hydroxylase specific activities of the ACI/Pit, F344/Pit, OKA/Pit, and MNR/N strains. Six of the 20 mouse strains were Ah-nonresponsive (i.e. lacking the normal induction response and presumably lacking detectable amounts of the Ah receptor). The basal hydroxylase specific activities of the BDL/N, NFS/N, STAR/N, and ST/JN mouse strains were more than twice as high as the maximally induced hydroxylase specific activity of the CBA/HT strain.——To date, 24 Ah-nonresponsive mouse strains have been identified, out of a total of 68 known to have been characterized. The reasons for not finding a single Ah-nonresponsive inbred rat strain—as compared with about one Ah-nonresponsive inbred mouse strain found for every three examined—remain unknown.

scholarly journals Photoaffinity labeling of the nuclear Ah receptor from mouse Hepa 1c1c7 cells using 2,3,7,8-[3H]tetrachlorodibenzo-p-dioxin

1989 ◽  
Vol 264 (31) ◽  
pp. 18463-18471
Author(s):  
J P Landers ◽  
J Piskorska-Pliszczynska ◽  
T Zacharewski ◽  
N J Bunce ◽  
S Safe
Keyword(s):  
Photoaffinity Labeling ◽  
Ah Receptor ◽  
Tetrachlorodibenzo P Dioxin

Ah receptor involvement in mediation of pyruvate carboxylase levels and activity in mice given 2,3,7,8-tetrachlorodibenzo-p-dioxin

1995 ◽  
Vol 10 (2) ◽  
pp. 103-109 ◽  
Author(s):  
Byung-Woo Ryu ◽  
Shukla Roy ◽  
Barney R. Sparrow ◽  
Daniel P. Selivonchick ◽  
Henry W. Schaup
Keyword(s):  
Pyruvate Carboxylase ◽  
Ah Receptor ◽  
Tetrachlorodibenzo P Dioxin

scholarly journals Cloning and Selective Expression in Brain and Kidney of ARNT2 Homologous to the Ah Receptor Nuclear Translocator (ARNT)

1996 ◽  
Vol 225 (2) ◽  
pp. 333-339 ◽  
Author(s):  
Guillaume Drutel ◽  
Markus Kathmann ◽  
Anne Heron ◽  
Jean-Charles Schwartz ◽  
Jean-Michel Arrang
Keyword(s):  
Ah Receptor ◽  
Selective Expression

Effect-Directed Assessment of the Bioaccumulation Potential and Chemical Nature of Ah Receptor Agonists in Crude and Refined Oils.

2012 ◽  
Vol 46 (3) ◽  
pp. 1572-1580 ◽  
Author(s):  
Cozmina M. Vrabie ◽  
Theo L. Sinnige ◽  
Albertinka J. Murk ◽  
Michiel T. O. Jonker
Keyword(s):  
Chemical Nature ◽  
Ah Receptor ◽  
Receptor Agonists
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