Distribution, Tissue Binding and Toxicity of Mercurials

Advances in Experimental Medicine and Biology - Protein-Metal Interactions ◽

10.1007/978-1-4684-0943-7_22 ◽

1974 ◽

pp. 463-503 ◽

Cited By ~ 23

Author(s):

J. T. MacGregor ◽

T. W. Clarkson

Keyword(s):

Tissue Binding

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Studies on the Intracellular Distribution and Tissue Binding of Dihydromorphine-7,8-H3 in the Rat

Experimental Biology and Medicine ◽

10.3181/00379727-122-31036 ◽

1966 ◽

Vol 122 (1) ◽

pp. 6-11 ◽

Cited By ~ 25

Author(s):

D. Van Praag ◽

E. J. Simon

Keyword(s):

Intracellular Distribution ◽

Tissue Binding

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Dose-Dependent Hepatic Handling of l-Propranolol Determined by Multiple Indicator Dilution Method: Influence of Tissue Binding of l-Propranolol on Its Hepatic Elimination.

Biological and Pharmaceutical Bulletin ◽

10.1248/bpb.16.1019 ◽

1993 ◽

Vol 16 (10) ◽

pp. 1019-1024 ◽

Cited By ~ 8

Author(s):

Seiji MIYAUCHI ◽

Yasufumi SAWADA ◽

Tatsuji IGA ◽

Manabu HANANO ◽

Yuichi SUGIYAMA

Keyword(s):

Indicator Dilution ◽

Dilution Method ◽

Tissue Binding ◽

Hepatic Elimination ◽

Multiple Indicator Dilution ◽

Multiple Indicator ◽

Dose Dependent ◽

Multiple Indicator Dilution Method

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Determination of Volume of Distribution at Steady State with Complete Consideration of the Kinetics of Protein and Tissue Binding in Linear Pharmacokinetics

Journal of Pharmaceutical Sciences ◽

10.1002/jps.10539 ◽

2004 ◽

Vol 93 (2) ◽

pp. 364-374 ◽

Cited By ~ 43

Author(s):

Leonid M. Berezhkovskiy

Keyword(s):

Steady State ◽

Volume Of Distribution ◽

Tissue Binding ◽

Linear Pharmacokinetics ◽

Kinetics Of

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Enantioselective Plasma and Tissue Binding

Stereochemical Aspects of Drug Action and Disposition - Handbook of Experimental Pharmacology ◽

10.1007/978-3-642-55842-9_12 ◽

2003 ◽

pp. 289-311

Author(s):

P. J. Hayball ◽

D. Mauleón

Keyword(s):

Tissue Binding

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Biomimetic HPLC property measurements to estimate human in vivo distribution and tissue binding of drug discovery compounds

Journal of Nephrology & Renal Diseases ◽

10.4172/2576-3962-c1-006 ◽

2018 ◽

Vol 02 ◽

Author(s):

Klara Valko

Keyword(s):

Drug Discovery ◽

Tissue Binding ◽

In Vivo Distribution

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Physiologically Based Pharmacokinetic Modeling Involving Nonlinear Plasma and Tissue Binding: Application to Prednisolone and Prednisone in Rats

Journal of Pharmacology and Experimental Therapeutics ◽

10.1124/jpet.120.000191 ◽

2020 ◽

Vol 375 (2) ◽

pp. 385-396

Author(s):

Xiaonan Li ◽

Debra C. DuBois ◽

Richard R. Almon ◽

William J. Jusko

Keyword(s):

Pharmacokinetic Modeling ◽

Tissue Binding ◽

Physiologically Based Pharmacokinetic Modeling ◽

Nonlinear Plasma ◽

Physiologically Based Pharmacokinetic ◽

Physiologically Based

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Plasma and tissue binding of psychotropic drugs

Clinical Pharmacology in Psychiatry ◽

10.1007/978-1-349-05929-4_14 ◽

1981 ◽

pp. 173-176

Author(s):

M. H. Bickel ◽

U. E. Honegger

Keyword(s):

Psychotropic Drugs ◽

Tissue Binding

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Effect of Altered Tissue Binding on the Disposition of Barbital in the Isolated Perfused Rat Liver: Application of the Axial Dispersion Model

Journal of Pharmaceutical Sciences ◽

10.1021/js960481d ◽

1997 ◽

Vol 86 (11) ◽

pp. 1310-1314 ◽

Cited By ~ 5

Author(s):

Chen-Hsi Chou ◽

Malcolm Rowland

Keyword(s):

Rat Liver ◽

Dispersion Model ◽

Axial Dispersion ◽

Isolated Perfused Rat Liver ◽

Tissue Binding ◽

Perfused Rat Liver ◽

Axial Dispersion Model

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Mechanistic modeling of digoxin distribution kinetics incorporating slow tissue binding

European Journal of Pharmaceutical Sciences ◽

10.1016/j.ejps.2006.11.012 ◽

2007 ◽

Vol 30 (3-4) ◽

pp. 256-263 ◽

Cited By ~ 5

Author(s):

Michael Weiss

Keyword(s):

Mechanistic Modeling ◽

Tissue Binding ◽

Distribution Kinetics

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How Well Do Lipophilicity Parameters, MEEKC Microemulsion Capacity Factor, and Plasma Protein Binding Predict CNS Tissue Binding?

Journal of Pharmaceutical Sciences ◽

10.1002/jps.23081 ◽

2012 ◽

Vol 101 (5) ◽

pp. 1932-1940 ◽

Cited By ~ 11

Author(s):

Maciej J. Zamek-Gliszczynski ◽

Karen E. Sprague ◽

Alfonso Espada ◽

Thomas J. Raub ◽

Stuart M. Morton ◽

...

Keyword(s):

Protein Binding ◽

Plasma Protein Binding ◽

Plasma Protein ◽

Capacity Factor ◽

Tissue Binding ◽

Lipophilicity Parameters

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