A Method for Estimating Contact Time of Red Cells in Lung Capillaries from O2 and CO2 Concentrations in Rebreathing Air in Man

1987 ◽  
pp. 51-59
Author(s):  
M. Mochizuki ◽  
I. Shibuya ◽  
K. Uchida ◽  
T. Kagawa
Keyword(s):  
Contact Time ◽  
Red Cells ◽  
Co2 Concentrations ◽  
Lung Capillaries

Acellular hemoglobin solution enters compressed lung capillaries more readily than red blood cells

2000 ◽  
Vol 89 (3) ◽  
pp. 1198-1204 ◽  
Author(s):  
Robert L. Conhaim ◽  
Lance A. Rodenkirch ◽  
Kal E. Watson ◽  
Bruce A. Harms
Keyword(s):  
Red Blood Cells ◽  
Blood Cells ◽  
Hemoglobin Concentration ◽  
Red Cells ◽  
Red Cell ◽  
Hemoglobin Solution ◽  
Lung Inflation ◽  
Hemoglobin Mass ◽  
Lung Capillaries ◽  
Alveolar Septa

High lung inflation pressures compress alveolar septal capillaries, impede red cell transit, and interfere with oxygenation. However, recently introduced acellular hemoglobin solutions may enter compressed lung capillaries more easily than red blood cells. To test this hypothesis, we perfused isolated rat lungs with fluorescently labeled diaspirin cross-linked hemoglobin (DCLHb; 10%) and/ or autologous red cells (hematocrit, 20). Septal capillaries were compressed by setting lung inflation pressure above vascular pressures (zone 1). Examination by confocal microscopy showed that DCLHb was distributed throughout alveolar septa. Furthermore, this distribution was not affected by adding red blood cells to the perfusate. We estimated the maximum acellular hemoglobin mass within septa to be equivalent to that of 15 red blood cells. By comparison, we found an average of 2.7 ± 4.6 red cells per septum in zone 1. These values increased to 30.4 ± 25.8 and 50.4 ± 22.1 cells per septum in zones 2 and 3, respectively. We conclude that perfusion in zone 1 with a 10% acellular hemoglobin solution may increase the hemoglobin concentration per septum up to fivefold compared with red cell perfusion.

Tri‐axial all‐metal inertial microswitch with compliant stationary electrodes to prolong contact time

2014 ◽  
Vol 9 (8) ◽  
pp. 514-518 ◽  
Author(s):  
Wenguo Chen ◽  
Zhaoyu Wang ◽  
Yan Wang ◽  
Zhuoqing Yang ◽  
Guifu Ding ◽  
...  
Keyword(s):  
Contact Time

Differential Outcomes for Long Term ex vivo Lung Perfusion in a Porcine Model - With or without Red Cells?

2015 ◽  
Vol 63 (S 01) ◽  
Author(s):  
W. Sommer ◽  
M. Avsar ◽  
J. Salman ◽  
C. Kühn ◽  
I. Tudorache ◽  
...  
Keyword(s):  
Porcine Model ◽  
Ex Vivo ◽  
Lung Perfusion ◽  
Red Cells ◽  
Ex Vivo Lung Perfusion ◽  
Differential Outcomes

Tailoring Communications for Primary Care Settings

1998 ◽  
Vol 37 (02) ◽  
pp. 171-178 ◽  
Author(s):  
B. Glassman ◽  
B. K. Rimer
Keyword(s):  
Primary Care ◽  
Health Professionals ◽  
Contact Time ◽  
Behavioral Changes ◽  
Patient Specific ◽  
Specific Information ◽  
Medical Settings ◽  
Primary Care Settings ◽  
Professional Contact ◽  
Tailored Communications

AbstractIn more and more medical settings, physicians have less and less time to be effective communicators. To be effective, they need accurate, current information about their patients. Tailored health communications can facilitate positive patient-provider communications and foster behavioral changes conducive to health. Tailored communications (TCs) are produced for an individual based on information about that person. The focus of this report is on tailored print communications (TPCs). TPCs also enhance the process of evaluation, because they require a database and the collection of patient-specific information. We present a Tailoring Model for Primary Care that describes the steps involved in creating TPCs. We also provide examples from three ongoing studies in which TPCs are being used in order to illustrate the kinds of variables used for tailoring the products that are developed and how evaluation is conducted. TPCs offer opportunities to expand the reach of health professionals and to give personalized, individualized massages in an era of shrinking professional contact time.

Liquoid Induced Stasis and the Generalized Shwartzman Reaction

1979 ◽  
Vol 41 (04) ◽  
pp. 804-810 ◽  
Author(s):  
Knut Nordstoga
Keyword(s):  
Red Cells ◽  
Renal Lesions ◽  
Intravenous Injections ◽  
Shwartzman Reaction ◽  
Glomerular Capillaries

SummaryThe composition of the occlusive material within dilated glomerular capillaries, following intravenous injections of Liquoid in blue foxes, was studied electron microscopically; it was found that it mainly consisted of a debris in which disintegrated red cells constituted the major component. Damaged platelets and necrotic endothelial remnants were other components. These observations were interpreted as a result of glomerular stasis, and it was concluded that stasis in glomerular capillaries is a basic event in the development of the renal lesions accompanying the generalized Shwartzman reaction.

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